Clinical trials: sponsored by Mahidol University
Tooth Injuries, Dental Restoration, Permanent
Colour Match, Stability, and Patient's Satisfaction of Single-Shade Composites in Anterior Teeth
The goal of this observational study is to evaluate the clinical performance of a single-shade composite resin, used with an injection moulding technique, in restoring maxillary incisors affected by traumatic dental injury in…
- Trial name
- NCT07309653
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Obesity & Overweight
Impact of Exercise-derived Extracellular Vesicle in Blood and Physical Fitness Data in Overweight/Obesity Individuals
This project aims to study the effect of exercise in the obesity/overweight on the changes of physical fitness and blood components.
- Trial name
- Exercise (NCT07312344)
- Testing
- High-intensity interval training exercise on treadmill
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
HIV/AIDS, STD
Addressing the Continuum of Care Among High-risk Thai Men
Young Thai men who have sex with men (YMSM) are at high risk for HIV. However, the Thailand National HIV Strategy does not adequately cover HIV prevention for YMSM using specific methods relevant to them, and instead uses a…
- Trial name
- NCT05161689
- Testing
- HUG-M+
- Where
- 2 sites in Thailand
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cesarean Section, Epidural; Anesthesia
Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor
The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia.
- Trial name
- NCT04074005
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Cesarean Section Complications, Sleep Disturbance
Sleep Quality After Cesarean Delivery
Surgery causes poor sleep quality for several reasons eg. increasing stress hormonal production, pain, starvation, and environmental procedure namely noise, light, and nursing procedures.
- Conditions
- Cesarean Section Complications, Sleep Disturbance, Perioperative Complication
- Trial name
- NCT05757401
- Where
- Thailand
- Volunteers
- 286 people
- Sponsor
- Mahidol University
Cesarean Section Complications, Postpartum Hemorrhage
Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery
Postpartum haemorrhage is the common cause of maternal death worldwide. The primary purpose of this study is to identify the maternal outcomes after PPH.
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Anesthesia Complication, Blood Transfusion Complication
- Trial name
- NCT04833556
- Where
- Thailand
- Volunteers
- 649 people
- Sponsor
- Mahidol University
Postpartum Hemorrhage, Delivery Complication
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage.
- Conditions
- Postpartum Hemorrhage, Delivery Complication, Cesarean Section Complications, Perinatal Problems
- Trial name
- NCT07278037
- Testing
- Tranexamic acid
- Where
- Thailand
- Volunteers
- 648 people
- Sponsor
- Mahidol University
Rehabilitation, Physical Therapy
The Combined FIFA 11+ and Change of Direction Training
The study has investigated the effects of adding change of direction (COD) training to the FIFA 11+ on lower extremity performance in soccer players.
- Trial name
- NCT06262087
- Testing
- Change of direction training, FIFA 11+ program
- Where
- Cambodia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Gynecologic Surgical Procedures, Risk Assessment
Comparing CCI and POSSUM for Predicting Oncogynecologic Surgery Complications
With the global rates of gynecologic cancers on the rise, optimizing perioperative care is imperative. Accurate risk prediction is essential for enhancing patient care, directing preoperative interventions, and facilitating…
- Conditions
- Gynecologic Surgical Procedures, Risk Assessment, Perioperative Care
- Trial name
- NCT07287280
- Testing
- CCI score, POSSUM score
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Mahidol University
Therapeutic Exercise, Physical Therapy Techniques
Exercise With Audible Cues on Motor Unit Behavior in Athletes With Anterior Cruciate Ligament Reconstruction
The closed kinetic chain (CKC) of terminal knee extension exercise (TKE) is designed to activate VM activity for knee injury training.
- Conditions
- Therapeutic Exercise, Physical Therapy Techniques, Neuromuscular Function
- Trial name
- ACLR (NCT06662955)
- Testing
- audible cues, Exercise
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Mild Cognitive Impairment (MCI)
Cognitive-motor Training in Community-dwelling Older People With Mild Cognitive Impairment
As the global population ages, the prevalence of mild cognitive impairment (MCI) among older adults, which ranges from 5% to 40%, is expected to rise.
- Trial name
- NCT07241598
- Testing
- Smart±step cognitive-motor training
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Critical Illness, Septic Shock
Human Albumin for Resuscitation in Surgical Septic Shock: A Randomized Controlled Trial (ALBUS Study)
This study will test whether giving human albumin to keep the blood albumin level above 3.5 g/dL, in addition to standard care, improves survival in patients with surgical septic shock.
- Trial name
- ALBUS (NCT07212582)
- Testing
- Human Albumin 20% Solution, Standard Care (in control arm)
- Where
- Thailand
- Volunteers
- 304 people
- Sponsor
- Mahidol University
Stroke, Ischemic
The Effect of The Ten-Session Dual-tDCS On Lower-Limb Performance in Sub- Acute and Chronic Stroke
The present study aims to determine the effect of the ten-session dual tDCS combine with physical therapy on gait performance, balance, and lower limbs muscle strength in patients with subacute and chronic stroke.
- Trial name
- NCT04687033
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Perennial Allergic Rhinitis, Child, Only
As Needed Versus Regular Intranasal Corticosteroid in Children With Perennial Allergic Rhinitis
Allergic rhinitis in children is common. According to the international study of asthma and allergies in childhood (ISAAC) phase III, the global prevalence of allergic rhinitis among children is increasing to 40.1% and the…
- Trial name
- NCT05299086
- Where
- Thailand
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Inspiratory Effort, Mechanical Ventilation
Assessment of Respiratory Drive and Inspiratory Effort Across Pressure Support Levels in Patients After Major Abdominal Surgery
This physiological observational study will assess respiratory drive and inspiratory effort across varying levels of pressure support ventilation (PSV) in adult surgical ICU (SICU) patients after major abdominal surgery.
- Conditions
- Inspiratory Effort, Mechanical Ventilation, Major Abdominal Surgeries
- Trial name
- NCT07199881
- Testing
- Stepwise PSV adjustment protocol
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Acute Kidney Injury, Renal Tubulopathy
Prevention of Cisplatin-induced Nephrotoxicity
The research design is a prospective, randomized, controlled clinical trial in children to study effect of aminophylline in preserving renal function in oncologic patient received cisplatin either combined with other CMT or used…
- Trial name
- NCT06196853
- Testing
- Aminophylline
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Colonoscopy, Bowel Preparation
The Effect of Smartphone Application on the Quality of Bowel Preparation for Colonoscopy
The goal of this clinical trial is to learn about bowel preparation methods compared between standard techniques and enhanced education with application for elective colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation, Quality, Smartphone Application
- Trial name
- NCT06444724
- Testing
- APP
- Where
- Thailand
- Volunteers
- 488 people
- Sponsor
- Mahidol University
Cesarean Section Complications, Postpartum Hemorrhage
Obstetric Comorbidity Index in Postpartum Hemorrhage
The objective of this study is to examine the predictive capability of the Obstetric comorbidity index in the identification of severe maternal morbidity associated with postpartum hemorrhage in patients undergoing cesarean…
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Morbidity;Perinatal
- Trial name
- NCT06431204
- Testing
- Obstetric comorbidity index
- Where
- Thailand
- Volunteers
- 583 people
- Sponsor
- Mahidol University
Slow Transit Constipation, Colonic Transit
Validation of New Type Radiopaque Marker in The Evaluation of Colonic Transit Time
The goal of this clinical trial is to learn if the local made colonic transit capsule can be use to diagnose slow transit constipation.
- Conditions
- Slow Transit Constipation, Colonic Transit, Chronic Constipation, Colonic Transit Capsule
- Trial name
- NCT06850415
- Testing
- Siriraj gastrointestinal transit capsule, Sitz-Markers
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Decompensated Cirrhosis and Ascites
Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic Patients
The goal of this clinical trial is to compare the nutritional parameters after 12-week supplementation of branched-chain amino acids in cirrhotic patients with ascites and serum albumin less than 3 g/dL.
- Trial name
- NCT06121479
- Testing
- Branched-chain amino acid
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University