Clinical trials: sponsored by Mansoura University
Malignant Biliary Obstruction
EUS-Guided Choledochoduodenostomy Versus ERCP for Primary Biliary Decompression in Distal Malignant Biliary Obstruction
Malignant biliary obstruction commonly caused by pancreatic adenocarcinoma, cholangiocarcinoma and other etiologies like gallbladder carcinoma, hepatocellular carcinoma, lymphoma, and metastasis to regional solid organs and lymph…
- Trial name
- NCT04898777
- Testing
- Biliary drainage
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Posttraumatic Stress Disorder (PTSD)
Resilience Building Among Older Adults: the Heart Math Based Interventions for Posttraumatic Stress Disorder, Spirituality and Psychosocial Well-being
Resilience building among older adults: The Heart Math based interventions for posttraumatic stress disorder, spirituality and psychosocial well-being.
- Trial name
- Resilience (NCT06746818)
- Testing
- Heart Math interventions
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Posterior Urethral Valve
Efficacy and Safety of Tamsulosin for Children with Posterior Urethral Valve.
To determine whether there is a role for Tamsulosin, A Selective Alpha-1 Adrenergic Blocker, as therapy in children with Posterior Urethral Valve post valve ablation , and whether there are side effects involved.
- Trial name
- NCT06737016
- Testing
- Tamsulosin, Oxybutynin, Trimethoprim/sulfamethoxazole (TMP/SMZ)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Peri Implant Bone Loss
Effect of Two Different Digital Construction Techniques of Implant-assisted Overdentures
twenty patients received mandibular overdenture constructed by different construction techniques were classified equally and randomly into two groups peri implant bone loss was assessed by CBCT at baseline (T0), at1 year(T1), at…
- Trial name
- NCT06720389
- Testing
- peri implant bone loss was assessed by CBCT, posterior ridge resorption was assessed by CBCT
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Irreversible Pulpitis
Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis
This study evaluates the effectiveness of photobiomodulation (PBM) in conjunction with mineral trioxide aggregate (MTA) pulpotomy for treating irreversible pulpitis in immature first permanent molars.
- Trial name
- NCT06730360
- Testing
- MTA Pulpotomy without photobiomodulation, MTA Pulpotomy with Photobiomodulation (LLLT)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Obstructed Defaecation Syndrome
Biofeedback Therapy Versus Botox Injection in Treatment of Dyssynergic Defecation.
assessment the Improvement symptoms of obstructed defecation after biofeedback training versus botulinum toxin injection
- Trial name
- NCT06724250
- Testing
- Biofeedback therapy, Botulinum Toxin A (Botox )
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Mansoura University
Occlual Caries, Proximal Caries
Clinical Evaluation of Self-Adhesive Bulk-Fil Hybrid Composite in Primary Molars
This study will evaluate the clinical performance of self-adhesive bulk-fill composite resin in the restoration of occlusal and occluso-proximal lesions in primary molars with hypothesis that there is no difference in the…
- Trial name
- NCT06724939
- Testing
- self-adhesive bulk-fill resin composite
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
TMJ Disc Disorder
Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
- Trial name
- NCT06441279
- Testing
- intra-articular injection with Platelet lysate (PL)., intra-articular injection with Hyaluronic Acid.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prosthesis Durability
Ultrasound Investigation of Tongue Movement for Implant Overdenture
This study aimed to examine the impact of mandibular implant overdentures on tongue movement during mastication.
- Trial name
- NCT06705114
- Testing
- complete denture, implant overdenture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
One Lung Ventilation
Comparison of Three Methods of PEEP Titration During One Lung Ventilation in Prone Position
One-lung ventilation and prone positioning during thoracoscopic esophagectomy is associated with pulmonary complications so lung protection is strongly recommended.
- Trial name
- NCT05851612
- Testing
- constant PEEP, Driving pressure guided PEEP, oxygenation method guided PEEP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mansoura University
Prosthesis Survival
Prosthetic Management of All on Four Versus All on Six to Rehabilitate Completely Edentulous Maxillary Ridge Opposed by Natural Teeth
the aim of the study to compare the anterior maxillary bone index changes for patient rehabilitated with implant supported fixed prosthesis opposed by natural teeth
- Trial name
- NCT06114069
- Testing
- implant supported maxillary fixed prosthesis
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Recession, Localized
Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial
The goal of this clinical trial is to compare two different tunneling surgical technique in treatment of gingival recession using two different materials.
- Trial name
- NCT06065774
- Testing
- The Laterally Closed Tunnel Technique with SCTG, The Laterally Closed Tunnel Technique with collagen matrix mucograft, Modified Coronally Advanced Tunnel Technique with SCTG.
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Elective Cesarean Section, Preeclampsia
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg…
- Trial name
- NCT04370847
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Ureter Stone, Renal Stone
Duration Between Drainage and Ureteroscopic Lithotripsy
This study will be conducted to compare early (seven days) versus delayed (14-21 days) definitive ureteroscopic lithotripsy after initial drainage for obstructing ureteral or renal stones associated with infection.
- Conditions
- Ureter Stone, Renal Stone, Ureteric Obstruction
- Trial name
- NCT06101563
- Testing
- Early ureteroscopy, Delayed Ureteroscopy
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Chronic Kidney Diseases, Bone Diseases, Metabolic
Effect of Dapagliflozin on Renal Outcomes and Bone Mineral Disease in Non-diabetic Chronic Kidney Disease Patients
It is a randomized controlled trial in which 100 non diabetic chronic kidney disease (CKD) patient is being participated. Their estimated glomerular filtration rate (eGFR) between 25-75 ml/min/1.73 m2.
- Trial name
- NCT05735197
- Testing
- Dapagliflozin 10mg Tab
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Edentulism
Patient Satisfaction and Prosthetic Complications of Bar Locator Versus Bar Clip Attachments for Mandibular Two-Implant Overdentures
Purpose: This study evaluated patient satisfaction and oral health-related- quality of life (OHRQoL) with implant overdentures retained with bar locator versus bar clip attachment for mandibular two-implant overdentures.
- Trial name
- NCT06673186
- Testing
- overdenture
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulism
Patient Satisfaction and Oral Health-Related Quality of Life of Quadrilateral Versus Bilateral Linear Bar Designs for Four Implant Implant-Assisted Complete Mandibular Overdenture Regarding Peri-Implant Crestal Bone Loss
For this study, twenty patients were selected, and participants were randomly divided into two groups using random numbers produced in an Excel spreadsheet.
- Trial name
- NCT06673173
- Testing
- Implant
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anxiety
Evaluation of the Effectiveness of New Management Techniques in Reducing Dental Anxiety for Children Undergoing Pulpotomy
The goal of this clinical trial is to reduce dental anxiety for sixety six children undergoing pulpotomy in primary molars by using kaleidoscope glasses and Tell-Show-Play-Doh techniques and evaluation of behavior and anxiety…
- Trial name
- NCT06673030
- Testing
- Using Kaleidoscope glasses during pulpotomy procedures, The Play-Doh Doctor Drill 'n Fill toy set, Group 1 (Tell-Show-Do)
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontal Pocket
The Proposed Study Aims to Investigate the Impact of Adjunctive Vitamin D Gel Application on Gingival Crevicular Fluid Levels of Alkaline Phosphatase and Interleukin-8 in Periodontitis Patients Undergoing Phase 1 Periodontal Therapy. By Elucidating the Molecular Mechanisms Underlying the Therapeutic
The proposed study aims to investigate the impact of adjunctive vitamin D gel application on gingival crevicular fluid levels of alkaline phosphatase and interleukin-8 in periodontitis patients undergoing phase 1 periodontal…
- Trial name
- NCT06669026
- Testing
- vitamin D loaded Poly lactic-co-glycolic acid nanoparticles gel, vitamin D3 gel (regular non-nanoparticle form), only mechanical debridement
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bladder Cancer Stage I
Can Second Resection for pT1 Bladder Cancer be Avoided After Initial En-Bloc Resection With Negative Safety Margins
The goal of this [ Can second resection for pT1 bladder carcinoma be safely avoided after initial En-Bloc Resection with negative vertical and horizontal safety margins ? is to assess the impact of avoiding re TUR on Recurrence…
- Trial name
- NCT05969964
- Testing
- Avoid second resection after initial complete resection
- Where
- Egypt
- Volunteers
- 370 people
- Sponsor
- Mansoura University
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