Clinical trials: sponsored by Mansoura University
Muscle Relaxant
Small Doses Muscle Relaxant in General Anesthesia
This study will be held to assess the effect of minimal dose muscle relaxant on postoperative pulmonary function. The time to extubation in minutes will be the primary outcome as a clinical indicator of the return of muscle…
- Trial name
- relaxant (NCT04344262)
- Testing
- Atracurium Besylate regular dose, Atracurium Besylate minial dose
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Dexmedetomidine Analgesia, Knee Surgery
Intravenous Regional Analgesia of Dexmedetomidine
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism…
- Trial name
- Dexmedetomidin (NCT07131579)
- Testing
- Normal Saline, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Fluid Balance
Caval Aorta Index for Fluid Optimization in Traumatic Brain Injury
Traumatic brain injury is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed; management strategies must focus on preventing secondary injury by avoiding hypotension and hypoxia…
- Trial name
- CAI for fluids (NCT06940258)
- Testing
- ultrasound measurement of caval aorta index, control group
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Mansoura University
Equivalent Concentrations, Different Volumes
Different Volumes and Equivalent Concentrations of Bupivacaine in Erector Spinae Plane Block in Modified Radical Mastectomy
This study aimed to compare and evaluate the efficiency of different volumes and equivalent concentrations of bupivacaine in erector spinae plane block in reducing the Postoperative pain after modified radical mastectomy.
- Conditions
- Equivalent Concentrations, Different Volumes, Bupivacaine, Erector Spinae Plane Block
- Trial name
- NCT07872371
- Testing
- Erector spinae plane block with 10 ml of 0.25% isobaric bupivacaine, Erector spinae plane block with 20 ml of 0.25% isobaric bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Laparoscopic, Extended View
Laparoscopic Extended View Totally Extra Peritoneal (e.TEP) in Comparison to Traditional TEP Technique for Inguinal Hernia Repair
The aim of this prospective randomized clinical study is to compare effectiveness, feasibility and outcome between total extra peritoneal (TEP) and extended TEP (E-TEP) techniques in repair of inguinal hernia.
- Conditions
- Laparoscopic, Extended View, Totally Extra Peritoneal, Inguinal Hernia Repair
- Trial name
- NCT07872410
- Testing
- Totally extra peritoneal, Extended view totally extra peritoneal
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Mansoura University
Cardiac Anaesthesia, Cardiopulmonary Bypass
Comparison of Milrinone and Epinephrine on TAPSE
Cardiopulmonary bypass (CPB) is a critical technology in cardiac surgery, allowing for the temporary replacement of the heart and lung functions during intricate surgical procedures.
- Trial name
- Milrinone (NCT07144267)
- Testing
- Epinephrine, Milrinone Injection
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Mansoura University
Heart Failure
Finerenone Plus SGLT2 Inhibitors in Heart Failure
The goal of this clinical study is to evaluate whether adding finerenone to standard treatment with a sodium-glucose cotransporter-2 (SGLT2) inhibitor provides additional benefits in patients with heart failure.
- Trial name
- FIN-SGLT2-HF (NCT07351864)
- Testing
- Finerenone, dapagliflozine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Mandibular Fractures
Custom-Made Titanium Plates Versus Custom-Made Polyether Ether Ketone (PEEK) Plates
Mandibular fractures represent a significant portion of maxillofacial trauma, primarily resulting from motor vehicle accidents, interpersonal violence, and sports-related injuries.
- Trial name
- NCT07850570
- Testing
- Custom-Made Titanium Plate, Custom-Made PEEK Plate
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Postpartum Hemorrhage, Uterine Atony
Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial
Background: Carbetocin is an established single-dose uterotonic agent for postpartum hemorrhage prophylaxis at elective cesarean delivery.
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Cesarean Section, Blood Loss, Surgical
- Trial name
- CARBOXY-RCT (NCT07636421)
- Testing
- Carbetocin, Oxytocin
- Where
- Saudi Arabia
- Volunteers
- 332 people
- Sponsor
- Mansoura University
Alveolar Bone Loss
Biologically Oriented Alveolar Ridge Preservation (BARP) With and Without Advanced Platelet-Rich Fibrin Plus (A-PRF+)
Twenty patients were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University seeking for extraction of non-restorable maxillary premolar teeth prior to…
- Trial name
- NCT07869082
- Testing
- Socket preservation by deproteinized bovine bone graft, socket preservation by deproteinized bovine bone graft mixed with advanced PRF+
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Accuracy
Digital Impression Techniques of Full Arch Implant-supported Screw-retained Restoration
aim: to compare the accuracy of the conventional and digital impression when will be performed on implant level or abutment level in Complete digital workflow for construction of full arch implant supported screw-retained…
- Trial name
- NCT06067334
- Testing
- full arch implant supported screw retained restoration with conventional impression technique, full arch implant supported screw retained restoration with conventional digital technique
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bronchial Asthma, Childhood Asthma
Effect of Multimedia Protocol About Asthma Control
This study aims to evaluate the effect of multimedia protocol about asthma control on asthmatic children's adaptation in the era of climate changes.
- Conditions
- Bronchial Asthma, Childhood Asthma, Climate Change, Multimedia Learning Education
- Trial name
- NCT06974331
- Testing
- Multimedia Protocol about Asthma Control
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Mansoura University
Edentulism, Dental Implants
Accuracy of the Calibrated Framework for Intra Oral Full Arch Scan (A Cross-over Study)
This crossover clinical trial aims to compare the accuracy of conventional splinted open-tray implant impressions with intraoral digital scanning using a calibrated framework in completely edentulous patients rehabilitated with…
- Trial name
- NCT07858682
- Testing
- Conventional Splinted Open-Tray Implant Impression, Intraoral Digital Scanning Using a Calibrated Framework
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Web Based Intervention
Web-based Health Education on Information, Motivation, Behavioral Skills Related to Human Papilloma Virus Vaccination
This study aims to evaluate the effect of web-based health education on information, motivation, behavioral skills related to human papilloma virus vaccination among female University students Research hypothesis Female…
- Trial name
- HPV Vaccine (NCT07857278)
- Testing
- Web-based IMB education delivered as daily modules
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Jaw, Edentulous, Partially, Bone Resorption
Clinical and Radiographic Evaluation of UV-Treated Dental Implants With or Without Melatonin in the Upper Posterior Jaw
The purpose of this study is to evaluate and compare the clinical and radiographic outcomes of using photofunctionalized (UV-treated) dental implants with or without the application of melatonin hormone in the posterior maxilla…
- Conditions
- Jaw, Edentulous, Partially, Bone Resorption, Dental Implant Failure
- Trial name
- UV-MEL-IMPLANT (NCT07853976)
- Testing
- UV-Photofunctionalized Dental Implant, Conventional Dental Implant
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Complete Edentulism
Titanium Versus Nano-Carbon CAD/CAM Frameworks for All-on-4 Implant Supported Hybrid Prosthesis.
This clinical study compares two CAD/CAM framework materials, titanium and nano-carbon fiber-reinforced composite, used in mandibular All-on-4 implant-supported hybrid prostheses.
- Trial name
- NCT07812363
- Testing
- Titanium CAD/CAM Framework, Nano-Carbon CAD/CAM Framework
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Participation Rate, Patient, Clinical Trials
Patients' Refusal to Participate in Surgical Research: Prevalence, Attributed Factors, and How to Overcome
This study aims to investigate the prevalence of refusal of participation in surgical clinical trials in our community. Furthermore, it aims to highlight potential factors contributing to refusal of participation.
- Trial name
- NCT07838285
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 372 people
- Sponsor
- Mansoura University
Class I Dental Caries
Two-year Clinical Performance of Ion-releasing and Conventional Bulk-fill Resin Composite Restorative Systems.
The goal of this clinical trial is to learn if ion-releasing composite works to induce remineralization in caries-affected dentin in adults.
- Trial name
- NCT07849478
- Testing
- self-cure ion-releasing bulk-fill resin composite, ion-releasing bulk-fill resin composite, conventional bulk-fill resin composite
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Class V Dental Caries
Two Year Clinical Performance of Ion-releasing and Non Ion-releasing Composite Restorative Systems in Restoring Cervical Carious Lesions.
The goal of this clinical trial is to learn if ion releasing composite materials works to induce remineralization of caries affected dentin in adults.
- Trial name
- NCT07849426
- Testing
- Ion-releasing resin composite, Giomer based composite, Non-ion-releasing ormocer based composite
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Jaw, Edentulous, Partially, Dental Implant Failure
Densah Bur Versus Modified Conventional Drilling in Early Loaded Maxillary Implants
This study aims to clinically and radiographically evaluate the efficacy of Densah burs (osseodensification) compared to the modified conventional drilling technique for early-loaded dental implants in the posterior maxilla.
- Conditions
- Jaw, Edentulous, Partially, Dental Implant Failure, Bone Resorption
- Trial name
- NCT07850583
- Testing
- Densah Bur Osseodensification, Modified Conventional Drilling
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
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