Clinical trials: sponsored by Mansoura University
Cancer
Efficacy of Memantine in Prevention of Oxaliplatin-induced Peripheral Neurotoxicity
Memantine is a drug for the management of Alzheimer's Disease (AD) due to its promising neuroprotective properties. We hypothesize that Memantine possesses a beneficial role against chemotherapy-induced neuronal damages.
- Trial name
- NCT05834231
- Testing
- Memantine
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Partial Edentulism Class 2 Due to Periodontal Disease
Management of Distally Extension Maxillary Atrophied Ridge With Two Different Minimal Invasive Treatment Modalities
This study will compare clinical and radio graphic outcomes of two minimally invasive different treatment modalities for atrophied unilateral distal extension maxillary ridges these modalities include 1.
- Trial name
- NCT05646498
- Testing
- Closed sinus lift procedure, Crestal sinus lift
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Uterine Diseases
Laparoscopic Versus Vaginal Cuff Closure During LH in Benign Gynecological Lesions
To compare vaginal cuff closure via Bakay purse string with vaginal cuff closure via vaginal route with continuous locked suturing after total laparoscopic hysterectomy for benign lesions.
- Trial name
- NCT05823935
- Testing
- Bakay purse string, Cuff closure via vaginal route group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Prosthesis Durability
Direct Versus Indirect Pick up of the Locator Retentive Caps:(Within-patient Study)
The purpose of this study will be to evaluate the effect of direct and indirect pick up of the locator retentive caps and compare the clinical results with those of the manufacturer retentive force.
- Trial name
- NCT05289752
- Testing
- dental implants in the mandible, locator attachment and overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Photodynamic Therapy
Clinical and Radiographic Evaluation of Photodynamic Therapy for Root Canal Treatment of Primary Molars
This study will be conducted to evaluate clinical and radiographic success of Photodynamic Therapy for root canal treatment of primary molars in comparison to the standard root canal treatment.
- Trial name
- NCT05820750
- Testing
- photodynamic therapy, pulpectomy with metapex
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
BPH
Comparison Between Tamsulosin and Tadalafil in Management of Benign Prostatic Hyperplasia Long Term Study
Comparison between tamsulosin and Tadalafil in management of benign prostatic hyperplasia A Randomised Trial
- Trial name
- NCT05818670
- Testing
- Tamsulosin, Tadalafil
- Where
- 2 sites in Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Effects of Different Treatment Modalities for Obstructive Sleep Apnea on Temporomandibular Joint
this study aims to evaluate the subjective symptoms, clinical and radiographic signs of temporomandibular disorders related to the use of CPAP, MAD and physical therapy in the treatment of patients with obstructive sleep apnea.
- Trial name
- NCT05510882
- Testing
- different treatment modalities for OSA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Stones, Kidney
Optimal Drainage After Flexible Ureterorenoscopy; Prospective Assessment of Perioperative Outcomes and Health-Related Quality of Life Through a Randomized Controlled Trial
Flexible ureterorenoscopy (FURS) is now recommended for the treatment of kidney stones smaller than 20 mm, as an alternative to extracorporeal shock wave lithotripsy (ESWL) and in combination with percutanous nephrolithotomy…
- Trial name
- NCT04643145
- Testing
- Flexible ureteroscopy for renal calculi less than 20 mm
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Mansoura University
Mandibular Fractures
Screw Retained Arch Bar Versus Conventional Erich's Arch Bar in Maxillomandibular Fixation
A randomized prospective clinical study to compare screw Retained Arch Bar and Conventional Erich's Arch Bar in Maxillomandibular Fixation
- Trial name
- NCT05401994
- Testing
- screw retained arch bar, conventional Erich's Arch Bar
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Septate Uterus, Recurrent Pregnancy Loss
Hysteroscopic Septoplasty by Different Modalities
The goal of this clinical trial is to compare in participant population ( women with uterine septum meeting the inclusion criteria) hysteroscopic septoplasty by resectoscope compared to hysteroscopic septoplasty with scissors.
- Conditions
- Septate Uterus, Recurrent Pregnancy Loss, Subfertility
- Trial name
- NCT05802784
- Testing
- Hysteroscopic septoplasty with scissors, Hysteroscopic septoplasty with resectoscope
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University Hospital
Efficacy, Self
Efficacy of Sublingual Versus Subcutaneous Allergen Immunotherapy in Patients With Bronchial Asthma
Asthma is characterized by airway inflammation and is manifested by acute episodes of obstruction related to loss of control of airway inflammation mostly in response to a viral respiratory tract infection .The significance of…
- Trial name
- Sublingual (NCT05786638)
- Testing
- Allergen Immunotherapy Extract
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University Hospital
Erectile Dysfunction Following Radiation Therapy, Phosphodiesterase Inhibitor Adverse Reaction
A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.
The aim of this study is to evaluate the efficacy and safety of intracavernosal injection of PRP in patients with moderate to severe ED.
- Conditions
- Erectile Dysfunction Following Radiation Therapy, Phosphodiesterase Inhibitor Adverse Reaction, Platelet- Rich Plasma (PRP)
- Trial name
- NCT05787769
- Testing
- P shot arm ( Autologous Platelet Rich Plasma), PDE5i arm
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Pediatric Thoracoscopy
Retrolaminar Block for Pediatric Thoracoscopic Sympathectomy
Thoracoscopic sympathectomy is a rapid and simple technique associated with rare complications, but it is associated with severe postoperative pain that makes breathing and coughing difficult resulting in increased occurrence of…
- Trial name
- NCT04688918
- Testing
- Retrolaminar block, paravertebral group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Peripheral Neuropathy, Breast Cancer
Efficacy of Cilostazol in Prevention of Peripheral Neuropathy
There are several mechanisms concerning pathophysiology of paclitaxel induced peripheral neuropathy. One of the main mechanisms is induction of Schwann cell dedifferentiation by paclitaxel.
- Trial name
- NCT05298696
- Testing
- Cilostazol
- Where
- Egypt
- Volunteers
- 71 people
- Sponsor
- Mansoura University
Anterior Openbite Malocclusion
Correction of Anterior Open Bite With Skeletally Anchored Extrusion Arch
This study will aim to evaluate the effect of skeletally anchored extrusion arch on the dentofacial structures in patients with anterior open bite (AOB).
- Trial name
- NCT05492864
- Testing
- extrusion of the anterior teeth
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Tamsulosin, Extracorporeal Shock Wave Lithotripsy
The Efficacy and Safety of Medical Expulsive Therapy After Extracorporeal Shock Wave Lithotripsy (ESWL) in Pediatric Urolithiasis
The aim of this study is to evaluate the clinical efficacy and safety of MET after ESWL in pediatric urolithiasis.
- Conditions
- Tamsulosin, Extracorporeal Shock Wave Lithotripsy, Stone, Kidney, Stone, Urinary
- Trial name
- NCT05759767
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Peripheral Neuropathy, Breast Cancer
Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients
At present, there are no FDA-approved treatments for chemotherapy-induced neuropathy. Discrete neuro anti-inflammatory effects of metformin support its repurposing as a neuroprotective agent in patients with neurodegenerative…
- Trial name
- NCT05351021
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Zinc in Pediatric Sepsis
Zinc Supplementation in Pediatric Sepsis
a single blinded randomized controlled clinical trial that was conducted to evaluate the role of zinc supplementation in improving the outcome of infants and children with sepsis in pediatric intensive care unit.
- Trial name
- NCT05366595
- Testing
- oral zinc sulfate
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Anal Fissure, Corona Virus Infection
Anal Fissure Among Survivors of COVID-19 Virus Infection.
Background Anal fissure is one of the most common anorectal problems. After an outbreak of coronavirus disease (COVID-19) has rapidly spread from China to almost all over the world, it nearly affected all countries.
- Trial name
- NCT05736926
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Mansoura University
Inferior Turbinate Hypertrophy
Medial Flap Coblation Turbinoplasty Versus Submucous Resection
Both submucous resection and medial flap coblation turbinoplasty are equally effective and safe in relieving nasal obstruction and enabling optimal volume reduction with preservation of function of the inferior turbinate.
- Trial name
- NCT05738512
- Testing
- Medial Flap Coblation Turbinoplasty, Submucous Resection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
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