Clinical trials: sponsored by Mansoura University
Hematological Malignancy (Leukemia- Lymphoma)
Ketamine-ketorolac Versus Fentanyl- Ketorolac I.M in Children During Bone Marrow Biopsy
investigators aim to compare between anaesthetic regimens that included dual-agent (fentanyl and ketorolac) or (ketamine and ketorolac) analgesic therapy
- Trial name
- NCT03649334
- Testing
- ketamine-ketorolac, fentanyl- ketorolac
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Labor Pain, Full Term Pregnancy
Patient Controlled Remifentanil Analgesia for Normal Labour
Patient controlled remifentanil analgesia might offer comparative overall patient satisfaction and improved quality of analgesia after normal labour with continuous epidural analgesia.
- Trial name
- NCT04541719
- Testing
- Patient-controlled remifentanil analgesia, Epidural analgesia
- Where
- Egypt
- Sponsor
- Mansoura University
Cleft Lip
Dexmedetomidine as Adjuvant for Bupivacaine in Ultrasound Guided Infraorbital Nerve Block for Cleft Lip Repair
To assess the efficacy of dexamethasone versus dexmedetomidine as adjuncts to bupivacaine for infra-orbital nerve block in infants undergoing cleft lip surgery.
- Trial name
- NCT03480607
- Testing
- Dexmedetomidine group, Dexamethasone group
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Mansoura University
Chronic Post-thoracotomy Pain
Pregabalin Versus Pulsed Radiofrequency Ablation for Treatment of Chronic Post-thoracotomy Pain
Chronic Post thoracotomy pain syndrome (PTPS) is defined PTPS as pain that develops or increases in intensity after a thoracotomy and persists beyond the healing process, that's to say at least 3 months after the initiating…
- Trial name
- NCT03942796
- Testing
- lyrica, vronogabic (pregabalin), pulsed radiofrequency ablation of the dorsal root ganglion under fluroscopic guidance/ radiofrequency neurolysis/ radiofrequency denervation device name: Neuro Therm TM 1100
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Obesity, Bariatric Surgery Candidate
Perioperative Systemic Lidocaine for Enhanced Bowel Recovery After Bariatric Surgery
Increasing rates of obesity over the last few decades have led to growing demand for bariatric surgery, which may resulted in decreased comorbidities and improved patient outcomes.
- Trial name
- NCT02607488
- Testing
- Lidocaine 1%, Lidocaine 1.5%, Lidocaine 2%
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Mansoura University
Valve Heart Disease, Elective Cesarean Delivery
Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery
Rheumatic heart valve diseases are prevalent among the young people in Egypt secondary to the socioeconomic conditions. The goal of anesthetic management of these patients is maintenance of sinus rhythm, systemic blood pressure…
- Trial name
- NCT01571791
- Testing
- Ketorolac-Lidocaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Laparoscopic Cholecystectomy
Analgesic Effect of Erector Spinea Plane Block Compared to Peritoneal Block in Laparoscopic Cholecystectomy
The aim of this study is to detect weather peritoneal block or erector spinae plane block will provide the most ideal analgesia for patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04064138
- Testing
- Peritoneal block, Ultrasound guided erector spinae plane block, General anesthesia
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Magnesium Infusion in Post-spinal Opioid Pruritis
Effect of Intravenous Magnesium on Post-spinal Fentanyl Induced Pruritus Incidence
Introduction: Adding opioids to local anesthetic solutions leads to enhanced anesthesia and provide postoperative analgesia. Intrathecaly injected opioids have some side effects, though. One of them is pruritus.
- Trial name
- NCT04160598
- Testing
- IV infusion, intrathecal fentanyl
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Mansoura University
Ruptured Cerebral Aneurysm
Effect of Propofol Midazolam on Cerebral Oxygenation and Metabolism During Clipping of Ruptured Cerebral Aneurysm
Despite the theoretical benefits of i.v. agents, volatile agents remain popular. In a study comparing desflurane, isoflurane, and sevoflurane in a porcine model of intracranial hypertension, at equipotent doses and normocapnia…
- Trial name
- NCT03778723
- Testing
- Total intravenous anesthesia (TIVA), Inhalation Anesthesia, Rescue fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Closed Non Comminuted Long Bone Fractures
Continuous Lornoxicam Infusion for Orthopaedic Surgery
Perioperative continuous infusion of lornoxicam would be an effective and safe regimen to reduce the patient controlled morphine consumption after orthopaedic surgery.
- Trial name
- NCT01718756
- Testing
- Continuous infusion, Scheduled
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
COVID, Drug Effect
New Antiviral Drugs for Treatment of COVID-19
Background: In December 2019, SARS-CoV-2 was isolated on Vero E6 and Huh7 cell lines after an outbreak of pneumonia of unknown origin in Wuhan, Hubei Province, China.
- Trial name
- NCT04392427
- Testing
- Treatment group: will receive a combination of Nitazoxanide, Ribavirin and Ivermectin for a duration of seven days :
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Pain, Chronic
CT-guided Ablation of the Ganglion Impar for Pelvic Tumors: Comparethe Addition of Ketorolac or Dexamethasone
this study investigator will resaearsh about the efficacy of addition of ketorlac or dexamethasone to alcohol in ablation of ganglion impar in pelvic tumour to asses thier efficacy in increasing the intensity or the duration of…
- Trial name
- NCT03789227
- Testing
- ganglion impar block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Cesarean Section, Uterine Fibroid
Myomectomy During CS: A Retrospective Cohort Study
To evaluate the value of myomectomy during delivery by cesarean section (CS) in pregnant women with uterine fibroids.
- Trial name
- NCT03270605
- Testing
- Myomectomy
- Volunteers
- 178 people
- Sponsor
- Mansoura University
Acute Renal Colic, Ureteric Stone
Parecoxib vs Paracetamol in the Treatment of Acute Renal Colic
This study will be conducted to compare the efficacy and safety of Parecoxib versus Paracetamol for treatment of acute renal colic due to ureteric stones.
- Trial name
- NCT03704623
- Testing
- Paracetamol, Parecoxib
- Where
- Kuwait
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Infertility, Fibroid
Effect of Myomectomy for Intramural Myoma on Fertility Outcomes in Infertile Women
The aim of this study is to evaluate the effect of myomectomy for intramural myomas on the fertility outcomes in infertile women.
- Trial name
- NCT03143114
- Testing
- Myomectomy
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Cholecystitis; Gallstone
Laparoscopic Versus US-Guided Subcostal TAP Block After Laparoscopic Cholecystectomy
Zaghiyan et al hypothesized that Laparoscopic TAP was noninferior to US-TAP and performed a randomized clinical trial comparing Laparoscopic TAP, US-TAP, and no TAP in minimally invasive colorectal surgery.
- Trial name
- NCT04276285
- Testing
- Laparoscopic TAP, US TAP
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Mansoura University
Hernia, Ventral, Hernia Incisional
Transversus Abdominis Muscle Release Versus Mesh Only Repair in the Treatment of Complex Ventral Wall Hernia
This trial was designed as a prospective randomized, controlled, intervention, with two parallel groups, and a primary endpoint of recurrence during 12 months' follow-up after initial treatment, with the randomization, was…
- Conditions
- Hernia, Ventral, Hernia Incisional, Hernia, Abdominal
- Trial name
- NCT04516031
- Testing
- Posterior Component Separation with Transversus Abdominis Muscle Release, Mesh-only repair
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Mansoura University
Rectocele
Vertical Versus Horizontal Plicataion in Transperienal Repair of Rectocele
We assumed that the technique of plication of the rectovaginal septum and rectal wall may factor in providing better and more sustained repair that confers more satisfactory improvement in symptoms.
- Trial name
- NCT04502953
- Testing
- Vertical plication, Horizontal plication
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Rectal Cancer
Early-onset Rectal Cancer
The present study aimed to review the characteristics and outcome of early-onset rectal cancer in a subset of Egyptian patients aged 40 years or less.
- Trial name
- NCT04496765
- Testing
- Total mesorectal excision
- Where
- Egypt
- Volunteers
- 244 people
- Sponsor
- Mansoura University
Varicose Veins
Microwave Venous Ablation in Comparison to Radiofrequency Ablation, Laser Ablation and Surgical Ligation in Management of Great Saphenous Vein Incompetence
The authors will aim to compare microwave therapy with other lines of management radio-frequency ablation, Laser ablation and surgical ligation; regarding time to recurrence rate, ulcer-free time, and health-related quality of…
- Trial name
- NCT04479956
- Testing
- Varicose vein surgery
- Where
- 2 sites in Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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