Clinical trials: sponsored by Mansoura University
Breast Cancer
Preoperative Localization of Sentinel Lymph Node in Breast Cancer Patients By Novel Computed Tomography-Lymphography Guided Technique
A question is raised about the possibility of accurate localization of the SLN (sentinel lymph node) detected by CTLG (Computed Tomography Lymphography) which offers a detection rate of 100% in many studies In Oncology center…
- Trial name
- NCT03442543
- Testing
- preoperative localization of SLN detected by CTLG by either methods
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
End Stage Renal Disease
Role of Double Cuffed PTFE Arteriovenous Grafts in Enhancing Long-term Patency in Hemodialysis Patients (Extended Poly Tetra Fluoro Ethylene)
this randomized controlled trial will compare the double vein cuffed synthetic arteriovenous graft to the single vein cuffed synthetic and the non cuffed synthetic as regard to long-term patency of each modality
- Trial name
- ePTFE (NCT03405233)
- Testing
- Double vein cuffed ePTFE graft both at the inflow and outflow ends, single vein cuffed eTFE graft both at the inflow and outflow ends, ePTFE graft without any cuff
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Mansoura University
Anal Fissure
Posterolateral Versus Lateral Internal Anal Sphincterotomy for Chronic Anal Fissure
The present study aimed to compare the standard lateral internal sphincterotomy at 3 o'clock with posterolateral internal sphincterotomy at 5 o'clock in regards healing time, postoperative recurrence and complications…
- Trial name
- NCT03426449
- Testing
- posterolateral sphincterotomy, lateral sphincterotomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Morbid Obesity
Single-Anastomosis Plication Ileal Bypass for Morbid Obesity
The present study aims to explore the impact of combining laparoscopic greater curvature plication with a single gastro-ileal anastomosis in the same manner of single anastomosis sleeve ileal bypass on weight loss and…
- Trial name
- NCT03428386
- Testing
- Gastric plication ileal bypass
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Postoperative Pain
Lumbar Paravertebral in Hernia Surgery
An inguinal hernia is one of the most common disorders requiring surgical repair in pediatrics. The effective treatment of postoperative pain in infants and children is challenging.
- Trial name
- NCT03408184
- Testing
- Lumbar paravertebral group, The field block group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Oxidative Stress in Preterm Infants
Light Protection of TPN and Oxidative Stress in Preterm Infants
Urinary peroxides and plasma glutathione/glutathione disulfide (GSH/GSSG) ratio will be measured in preterm infants less than 32 weeks gestation before and 7 days after receiving either Light-protected (Group 1) or Light-exposed…
- Trial name
- NCT02694510
- Testing
- Light-protection of TPN solutions
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University Children Hospital
Hepatic Transplantation
Clamp-crush Technique Versus Harmonic Scalpel in Living Donor Hepatectomy
The purpose of this study is to determine whether clamp-crush technique for liver parenchymal transection is as safe as Harmonic scalpel device.
- Trial name
- KK_HS (NCT02853981)
- Testing
- Harmonic scalpel, Kelly clamp crush technique
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Lower Abdominal Oncologic Surgery
Epidural Steroids With Intrathecal Nalbuphine for Lower Abdominal Oncologic Surgery
Intraoperative pain, nausea, vomiting, hypotension, bradycardia are known side effects during lower abdominal surgery under spinal anesthesia, Time to 2 segment regression of sensory block and duration of effective analgesia…
- Trial name
- NCT03276325
- Testing
- Dexamethasone-nalbuphine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Bladder Cancer, Flexible Cystoscopy
Assessment Of Bladder Tumors Stage And Grade By Outpatient Flexible Cystoscopy Performed By Urology Resident
This will be a prospective trial comparing the perspective gross morphological of bladder tumor assessment done by outpatient flexible cystoscopy performed by resident, inpatient rigid cystoscopy done by senior staff and their…
- Conditions
- Bladder Cancer, Flexible Cystoscopy, Non-muscle Invasive Bladder Cancer (NMIBC), Pain, Postoperative
- Trial name
- NCT03148158
- Testing
- Cystoscopy
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Morbid Obesity
Boussignac Valve and Fibroptic Intubation in Morbidly Obese Patients, Can it be a Solution?
In this study, fiberoptic intubation through Boussignac valve, while ventilation of morbidly obese patients is maintained through the ventilator, will be studied.
- Trial name
- Obese-FOB (NCT03046797)
- Testing
- Fibroptic intubation through Boussignac valve opening, Classic Fibroptic intubation
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Overactive Bladder, Botulinum Toxin
Delivery of Intravesical Botulinum Toxin A Using Low Energy Shock Waves in Treatment of Overactive Bladder: A Feasibility Study
We hypothesize that LESWs might temporarily increase urothelial permeability and facilitate delivery of intravesical botulinum toxin without the need for injection.
- Conditions
- Overactive Bladder, Botulinum Toxin, Intravesical, ESWL
- Trial name
- NCT03385460
- Testing
- ESWL BOTOX
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Nocturnal Incontinence
Effect of Long Acting Anticholinergic on Nocturnal Incontinence After Radical Cystectomy and Orthotopic Neobladder
It is a prospective randomized- placebo control crossover study to evaluate the effect of long acting tolterodine (anticholinergic) in improving and treating nocturnal incontinence in patient after radical cystectomy and…
- Trial name
- NCT02877901
- Testing
- long acting tolterodine 4 mg
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Chronic Knee Osteoarthritis
Genicular Nerve and Intra-articular Radiofrequency Versus Platelet Rich Plasma Injection for Knee Osteoarthritis
The social impact of degenerative diseases such as articular cartilage pathology and osteoarthritis (OA) is steadily increasing, because of the continued rise in the mean age of the active population.
- Trial name
- NCT03379883
- Testing
- Pulsed radiofrequency (P-RF), Platelet rich plasma (PRP)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Periodontal Diseases
Melatonin as an Adjunctive Therapy for Chronic Periodontitis.
Background: Melatonin is an endogenous indoleamine synthesized mainly by pineal gland and showed anti-inflammatory and antioxidant properties.
- Trial name
- NCT03368430
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Mansoura University
Infertility, Polycystic Ovarian Syndrome
LOD Before IVF/ICSI in PCOS Patients With High AMH
To evaluate the effect of performing laparoscopic ovarian drilling (LOD) before proceeding to in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) on the cycle outcomes in polycystic ovarian syndrome (PCOS)…
- Trial name
- NCT03358199
- Testing
- LOD
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Indication of Cesarean Section
Robson Classification of Indications of Cesarean Section at MUH
Robson classification of Cesarean section rates and indications allows evaluation and comparison of the contributors to the Cesarean section rate and their impact.
- Trial name
- NCT03358615
- Testing
- cesarean section
- Where
- Egypt
- Volunteers
- 700 people
- Sponsor
- Mansoura University
Traumatic Brain Injury
Omega3 PUFA in Head Trauam
Traumatic brain injury (TBI) is major health problem that stands as a significant cause of death and permanent disability. TBI is considered as global public health epidemic.
- Trial name
- SMOFbrain (NCT02762539)
- Testing
- omega-3 enriched SMOF lipid emusion
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Postpartum Hemorrhage
Tranexamic Acid in Preventing Postpartum Hemorrhage in High Risk Pregnancies During Elective Cesarean Section
postpartum hemorrhage (PPT) represents one of the major causes of maternal mortality . Tranexamic acid is used in many studies in management of PPH in combination with ecobolics.
- Trial name
- NCT03351686
- Testing
- Tranexamic Acid
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Endometrial Disorder
Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding
Endometrial thickness has been used as an indicator of risk for endometrial hyperplasia and carcinoma in asymptomatic perimenopausal women.
- Trial name
- NCT03351673
- Testing
- endometrial volume 2D TVS
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Infertility, Male, Oligozoospermia
The Role of Artery-Preserving Varicocelectomy in Subfertile Men With Severe Oligozoospermia.
A male factor is responsible for almost half the cases of subfertility. Varicocele is a major cause of impaired spermatogenesis and potentially a correctable cause.
- Conditions
- Infertility, Male, Oligozoospermia, Varicocelectomy
- Trial name
- NCT03344588
- Testing
- artery preserving varicocelectomy, artery ligation varicocelectomy
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Mansoura University
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