Clinical trials: sponsored by Mansoura University
Periodontal Diseases, Periodontal Bone Loss
Adjunctive Antioxidant Effect of Centella Asiatica Nanoemulsion Gel in Management of Periodontitis
The aims of the current study are: 1. Evaluation of the clinical efficacy of local delivery of nanoemulsion gel containing Centella asiatica extract as an adjunct to conventional non-surgical periodontal therapy in periodontitis…
- Trial name
- NCT07697209
- Testing
- Centella asiatica nanoemulsion gel, Scaling and Root Planing (SRP)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Clinical Performance of Different Ion-Releasing Restorative Systems in Class II Cavities
Different ion-releasing restorative systems will be applied in class II cavities then their clinical performance will be evaluated and compared
- Trial name
- ION-REST II (NCT07688343)
- Testing
- conventional bulk fill restorative system, ion-releasing restorative system 1, ion-releasing restorative system 2
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulism, Complete Maxillary Edentulism
Jaw Tracking Impact on Occlusion and Patient Outcomes in Maxillary Implant Restorations
This randomized clinical trial aims to evaluate the effect of integrating digital jaw tracking into the workflow for fabrication of full-arch maxillary implant-supported screw-retained restorations.
- Trial name
- NCT07693946
- Testing
- Conventional Prosthetic Workflow, Digital Jaw-Tracking Workflow
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Critical Illness
Lactoferrin Use in ICU Patients
Introduction: Lactoferrin has several uses due to its effects. It has anti-inflammatory, antioxidant, immunomodulatory, antibacterial, antifungal, and antiviral effects. Its safety is proven by food and drug administration.
- Trial name
- RCT (NCT05936528)
- Testing
- Lactoferrin, Antioxidant therapies, Dexamethasone
- Where
- Egypt
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Brain Injuries,Traumatic
Effect of Implementing External Ventricular Drain Guidelines on Nurses' Practice and Traumatic Brain Injury Patients' Outcomes
Neurosurgical patients are more vulnerable to infections related to medical care due to their requirement for surgically inserted devices like ventriculostomies and their extended hospital stays.
- Trial name
- NCT07682987
- Testing
- External Ventricular Drain Guidelines
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Mansoura University
Tooth Loss and Rehabilitation With Telescopic Crown Prostheses
Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis
This study aims to compare the clinical and patient satisfaction outcomes of rigid versus non-rigid digitally fabricated telescopic double crown prostheses supported by teeth and implants.
- Trial name
- NCT07682623
- Testing
- Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Alveolar Ridge Deficiency
Custom-Made PEEK Versus PTFE Membranes in Maxillary Alveolar Ridge Augmentation
This randomized controlled clinical study aims to evaluate and compare the effectiveness of custom-made polyether ether ketone (PEEK) membranes versus polytetrafluoroethylene (PTFE) membranes in guided bone regeneration for…
- Trial name
- NCT07679451
- Testing
- Custom-made PEEK Membrane, PTFE Membrane
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Horizontal Alveolar Ridge Deficiency, Partial Edentulism
Carrot Technique Versus Guided Bone Regeneration for Horizontal Ridge Deficiency in the Maxillary Esthetic Zone
This randomized controlled clinical trial aims to compare the effectiveness of the Carrot Technique and Guided Bone Regeneration (GBR) for the management of horizontal alveolar ridge deficiency in patients requiring implant…
- Trial name
- NCT07670559
- Testing
- Carrot Technique, Guided Bone Regeneration
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Periodontal Disease, Stage III Periodontitis
Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients
the aim of this study is to investigate the clinical outcomes of Minimally Invasive Non-Surgical Therapy(MINST) compared to Conventional non-surgical periodontal therapy (CNST)
- Trial name
- NCT07671274
- Testing
- Mechanical debridement ., minimally invasive mechanical debridement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Estimation of Bone Height Changes
Comparison Between Digital And Direct Pickup Of Attachments With Digitally Constructed 2-Implant Overdenture Bases
Comparing digital attachment pickup prior to jaw relation registration with intraoral pickup using digitally constructed mandibular overdenture bases is the aim of this study.
- Trial name
- NCT07238335
- Testing
- digital pickup of attachment before jaw relation, intraoral pickup of attachment during insertion
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Stone Heterogeneity Index, Shock Wave Lithotripsy
Stone Heterogeneity Index and Shock Wave Lithotripsy Outcomes in Pediatrics
To assess the role of SHI in SWL outcomes for upper urinary tract calculi in pediatric population.
- Trial name
- SHI/SWL (NCT07657832)
- Where
- Egypt
- Volunteers
- 286 people
- Sponsor
- Mansoura University
Marital Relationship
Effect of Marital Adjustment Strategies on Emotional Divorce Among Married Women
Aim: The current study aims to evaluate the impact of marital adjustment strategies on emotional divorce among married women. Design: A mixed design consisting of a cross-sectional study and a quasi-experimental one-group…
- Trial name
- NCT07652411
- Testing
- Educational Program; Marital Counseling Program
- Volunteers
- 320 people
- Sponsor
- Mansoura University
Periodontal Disease, Periodontitis Stage II
Assessment of Spirulina Gel Prepared By Different Extraction Methods as an Adjunctive Therapy to Mechanical Debridement in the Treatment of Stage II Grade B Periodontitis
I) Patients: the present study will be carried on periodontitis patients. The patients will be informed about the treatment steps.
- Conditions
- Periodontal Disease, Periodontitis Stage II, Periodontal Therapy
- Trial name
- NCT07647874
- Testing
- Mechanical debridement will be performed for 15 stage II periodontitis patient, spirulina gel extracted by phosphate buffered saline (PBS)., spirulina gel exracted by 1.5% calcium chloride (CaCl2) aqueous solution.
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prostheses Durability
Triple-Scan Protocol to Assess Passivity
Quantification and visualization the internal and marginal gaps by newer digital methods, such as the triple-scan protocol described by Borga Dönmez et al.
- Trial name
- NCT07644689
- Testing
- Conventional Impression Technique, Digital Impression with Nonmodified Scan Body, Digital Impression with Modified Scan Body
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
3-D Printed Resin Composite Versus Milled Resin Composite and Hybrid Ceramic Onlays: 2-Year Clinical Performance, Microtensile Bond Strength, Marginal and Internal Adaptation
Study Protocol Background The use of partial coverage restorations had increased significantly as a conservative alternative to full-coverage crowns, particularly in cases where the coronal tooth structure was extensively damaged…
- Trial name
- NCT07633717
- Testing
- 3D printed CAD/CAM hybrid resin onlay.Milled CAD/CAM hybrid ceramic onlay (Vita Enamic)Indirect resin composite onlay.
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Chronic Rhinosinusitis (CRS), Emergence Agitation
Trans-nasal Sphenopalatine Ganglion Block for Prevention of Emergence Agitation Following Functional Endoscopic Sinus Surgery
This randomized double-blind controlled trial aims to evaluate whether bilateral trans-nasal sphenopalatine ganglion block (SPGB) using bupivacaine reduces the incidence of emergence agitation following Functional Endoscopic…
- Trial name
- SPGB-EA (NCT07645521)
- Testing
- Bilateral Trans-nasal Sphenopalatine Ganglion Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Nephrotic Syndrome
SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome
This randomized controlled clinical trial aims to evaluate the efficacy and safety of sodium-glucose cotransporter 2 (SGLT2) inhibitors (dapagliflozin and empagliflozin) in adult patients with primary nephrotic syndrome.
- Trial name
- SGLT2-NS (NCT07214818)
- Testing
- Dapagliflozin, Empagliflozin, Standard Therapy
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Periodontal Disease, Periodontitis
Assessment of Ozonated Sunflower Seed Oil Gel as an Adjunctive Therapy to Mechanical Debridement in the Treatment of Stage II Grade B Periodontitis
I) Patients: The present study will be carried on periodontitis patients. The patients will be informed about the treatment steps.
- Conditions
- Periodontal Disease, Periodontitis, Periodontitis Stage II
- Trial name
- NCT07636993
- Testing
- Mechanical debridement ., sun flower, ozonated sun flower
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Jaw Edentulous
Patient Satisfaction and Prosthetic Complications of the Milled Bar Versus Screw-Retained Prostheses for Maxillary Subperiosteal Implants: A One Year Randomized Clinical Trial
This study aims to evaluate and compare patient satisfaction and prosthetic complications between two types of prostheses: milled bar and screw-retained prostheses, used for supporting maxillary subperiosteal implants.
- Trial name
- NCT07632885
- Testing
- Maxillary subperiosteal implant with milled bar-retained prosthesis, Maxillary subperiosteal implant with screw-retained prosthesis
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Class V Restorations
Impact of Finishing/Polishing Systems on Ormocer VS Methacrylate Based Bulk Fill Flowable Composite in Class V
The goal of this clinical trial is to evaluate and compare. Impact of finishing/polishing systems on ormocer versus methacrylate-based bulk-fill flowable composite in Class V restorations: The main question it aims to answer is…
- Trial name
- NCT07627295
- Testing
- one-step finishing and polishing system., two-step finishing and polishing system., three-step finishing and polishing system.
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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