Clinical trials: sponsored by Mansoura University
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Stridor, Larynx Edema
Predicting Post Extubation Stridor After Maxillomandibular Fixation
Endotracheal intubation can induce laryngotracheal injury which results in narrowing of the airway due to edema of the glottis. This can increase the risk of development of post-extubation stridor (PES)
- Trial name
- airway (NCT05839756)
- Testing
- budesonide, normal saline
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Mansoura University
Dental Implant
Extended Platelet Rich Fibrin or Hyaluronate Enriched Xenografts for Horizontal Ridge Augmentation Via Subperiosteal Tunneling
Extended platelet rich fibrin or hyaluronate enriched xenografts will be used for horizontal maxillary ridge augmentation via subperiosteal tunneling to allow placement of dental implants six months later.
- Trial name
- E-PRF (NCT07412535)
- Testing
- bovine bone mixed with hyaluronate, bovine bone mixed with E-PEF
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Echocardiography
Cardiac Output in Preeclamptic
There is high incidence of hypertensive disorders during pregnancy.The maternal cardiovascular system had significant changes during pregnancy. The colloid oncotic pressure is decreased during preeclampsia.
- Trial name
- Coload (NCT05435573)
- Testing
- 1000 mL of ringer's acetate solution, 250 mL 6% hydroxyethyl starch (Voluven) then 500 mL of ringer's acetate solution then 250 mL of 6% hydroxyethyl starch (Voluven)
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Analgesia
Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia
Cesarean birth is a common surgical procedure. After cesarean birth, postsurgical pain may delay recovery, interfere with maternal-newborn bonding, and reduce the breastfeeding if not adequately controlled.
- Trial name
- TAB (NCT05785377)
- Testing
- Bupivacaine-Neostigmine, Bupivacaine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mansoura University
Analgesia
Maxillary and Mandibular Nerve Block
Mandibular fractures are among the most common (60-70%) maxillofacial fractures observed in emergency rooms. In the closed reduction (non-surgical), the bone fragments are realigned manually or by using traction devices.
- Trial name
- nerve block (NCT05925465)
- Testing
- Maxillary and mandibular nerve block, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Patient Satisfaction, Prosthetic Complication
Prosthetic Complications and Patient Satisfaction of Two Different Implant Distribution
Purpose: This clinical study aimed to evaluate patient satisfaction and prosthetic complications of different distributions of four implants supported mandibular overdentures using Stress free implant bar (SFI-Bar attachments).
- Trial name
- NCT07400380
- Testing
- four implants inserted in the mandible and distributed in quadrilateral manner and SFI-Bar had been inserted
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Injection Pain Prevention
Shot Blocker and Manual Pressure Application
Aim of my intervention to test the effectiveness of using the manual pressure application and shotblocker for relief insulin injection pain in children with type 1 diabetes mellitus
- Trial name
- NCT07407881
- Testing
- Manual pressure applied at injection site during insulin injection to reduce pain, Shotblocker, Control group stander care
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Mansoura University
Orthodontic Tooth Movement, Tooth Movement
Evaluation of the Biomechanical Response of Orthodontic Tooth Movement to Clear Aligner vs Fixed Orthodontic Appliance
Abstract Background: Orthodontic tooth movement (OTM) is mediated by biologic responses of the periodontal ligament (PDL) and alveolar bone to applied mechanical forces, involving release of inflammatory mediators such as…
- Trial name
- NCT07399483
- Testing
- diagnostic Test: Collection of GCF: from the gingival sulcus using paper point ,Tooth Mobility via Periotest ,3D Digital Model Superimposition using Intraoral Scanning
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Tooth Extraction
IMMEDIATE IMPLANT With Different Types of Membrane
Forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area with…
- Trial name
- NCT07396350
- Testing
- immediate implant with dentin-derived barrier membrane, immediate implant with eprf membrane
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Immediate Provisional Prosthesis
This Study Aims to Evaluate the Soft Tissue Response and Prosthetic Complications Associated With Three Different Types of Provisional Prosthesis Used in Immediate Loading Full-arch Implant Prosthetic Treatment. The Patients Are Randomly Assigned to the Three Groups to Compare the Clinical Outcomes
This study aims to evaluate the soft tissue response and prosthetic complications associated with three different types of provisional prostheses used in immediate loading full-arch implant prosthetic treatment.
- Trial name
- NCT07395167
- Testing
- 3D printed provisional full arch prosthesis, Bar reinforced 3D printed provisional full arch prosthesis, Milled PMMA provisional full arch prosthesis
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Myogenic Temporomandibular Joint Disorders, Internal Derangement of the Tempromandibular Joint
Adjustment Technique for Occlusal Stabilizing Splint
This study aims to clarify the technique of occlusal stabilizing splint adjustment then to assess the overall clinical outcomes and patient satisfaction.
- Conditions
- Myogenic Temporomandibular Joint Disorders, Internal Derangement of the Tempromandibular Joint, Temporomandibular Disorders (TMDs), Temporomandibular Joint Disc Displacement
- Trial name
- NCT07397013
- Testing
- Stabilizing Splint(3-point of Contact), Stabilizing Splint (Centric and Eccentric)
- Where
- Egypt
- Volunteers
- 800 people
- Sponsor
- Mansoura University
Erectile Dysfunctions
Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients
The goal of this clinical trial is to evaluate whether daily dosing with tadalafil 5 mg combined with on-demand sildenafil 100 mg can improve erectile function in men with erectile dysfunction (ED) who do not respond to PDE5…
- Trial name
- NCT07391579
- Testing
- Tadalafil 5 mg & Sildenafil 100mg
- Where
- 11 sites in Egypt
- Volunteers
- 500 people
- Sponsor
- Mansoura University
Renal Stones, Renal Calculi > 2 cm
Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones
The investigator will compare between holmium laser setting during miniPCNL for renal stones as regard safety \& efficacy
- Trial name
- miniPCNL (NCT07393178)
- Testing
- mini percutaneous nephrolithotomy
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Urostomy Patients, Self-Care Practices
Stoma Educational Program on Self-Care Practices
provide a stoma educational program and evaluate the self-care practices and life satisfaction of urostomy patients.
- Trial name
- 0841 (NCT07370324)
- Testing
- education
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Edentulism
3D-Printed Implant Overdentures: Comparing Impression Techniques
This randomized crossover clinical trial aims to compare three different impression techniques for the construction of 3d-printed mandibular implant overdentures in completely edentulous patients.
- Trial name
- NCT07208812
- Testing
- Conventional open -tray impression, Functionally generated reline impression, Mucostatic base with functional borders impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Skeletal Class III Malocclusion
Management of Skeletal Class III Malocclusion With Digital Bonded Reverse Twin Block in Mixed Dentition
The purpose of this study is to evaluate dentoalveolar \& skeletal effects of digital bonded reverse twin block in treatment of skeletal class III malocclusion in mixed dentition.
- Trial name
- NCT07376954
- Testing
- Digital Bonded Reverse Twin Block
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Mansoura University
Insulin Dependent Diabetes Mellitus
Strategies to Minimize the Risk for Insulin Induced Hypertrophy and Its Related Consequences
Hypertrophy caused by insulin has effects that extend beyond just aesthetic concerns. Innovative methods have shown potential in decreasing the chances of hypertrophy and its related issues, including the development of detailed…
- Trial name
- NCT07375875
- Testing
- Group(1) Insulin site injection map
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Mansoura University
Edentulism
A Pilot Randomized Clinical Study Comparing Patient-Reported Outcomes and Complications for Mandibular Implant Overdentures Retained by Different Splinted Attachment Systems
This exploratory pilot randomized clinical study enrolled ten completely edentulous participants who experienced retention and stability problems with conventional mandibular complete dentures.
- Trial name
- M15011122 (NCT07373340)
- Testing
- overdentures with bar locator attachments, overdentures with bar ball attachments
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Immature Permanent Teeth With Open Apex, Pulp Necrosis
Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids
This clinical study will be conducted to evaluate the effect of using intracanal Omega-3 Fatty acids during revascularization of necrotic immature teeth compared to the traditional induced bleeding technique.
- Trial name
- Regeneration (NCT07371416)
- Testing
- Omega -3 fatty acids, Calcium Hydroxide (Ca(OH)2)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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