Clinical trials: sponsored by Marmara University
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Home Care Services, Home Health Care
Home Environmental Risks and Caregiver Awareness
This cross-sectional study aimed to assess home environmental risks and caregiver awareness among individuals receiving home healthcare services. It also examined factors associated with caregivers' awareness of these risks.
- Trial name
- NCT07645976
- Testing
- Observation
- Where
- Turkey (Türkiye)
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Peri-intubation Hypotension
Effect of Push-Dose Adrenaline on Peri-intubation Hypotension During Rapid Sequence Intubation in the Emergency Department
Rapid sequence intubation is commonly performed in the emergency department to secure the airway of critically ill patients. However, blood pressure may decrease during or shortly after intubation because of the patient's…
- Trial name
- NCT07620327
- Testing
- Adrenaline, 0.9 % sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Periodontitis, Diabetes Mellitus
Adjunctive Hyaluronic Acid Gel in Non-Surgical Periodontal Treatment of Patients With Diabetes Mellitus
The goal of this clinical trial is to evaluate whether the adjunctive use of hyaluronic acid (HA) improves periodontal healing in people with diabetes mellitus and periodontitis.
- Conditions
- Periodontitis, Diabetes Mellitus, Hyaluronic Acid, Oral Microbiota
- Trial name
- NCT07631273
- Testing
- Scaling and root planing, Hyaluronic Acid (HYADENT BG)
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Marmara University
Ankylosing Spondylitis (AS), Back Pain
Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis
Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing…
- Conditions
- Ankylosing Spondylitis (AS), Back Pain, ESPB, Regional Anesthesia
- Trial name
- NCT07633730
- Testing
- Erector spinae plane block(ESBP)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University
Molar-Incisor Hypomineralization (MIH), Masticatory Performance
Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization
This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Masticatory Performance, Occlusal Analysis, Chewing Function
- Trial name
- NCT07589179
- Testing
- Glass Hybrid Restorative Treatment
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Supraventricular Tachycardia, Paroxysmal Supraventricular Tachycardia
NASVAL-SVT: Nasal Swab Versus Modified Valsalva for Supraventricular Tachycardia
Supraventricular tachycardia (SVT) is a common heart rhythm disorder seen in emergency departments, causing a rapid heartbeat (typically 150-250 beats per minute).
- Conditions
- Supraventricular Tachycardia, Paroxysmal Supraventricular Tachycardia, Atrioventricular Nodal Reentry Tachycardia, Vagal Maneuver
- Trial name
- NASVAL-SVT (NCT07617077)
- Testing
- Nasopharyngeal Swab Insertion, Modified Valsalva Maneuver (REVERT Protocol)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Lumbar Spinal Stenosis
Hybrid vs Fluoroscopy-Guided Interlaminar Epidural Injection in Lumbar Spinal Stenosis
Lumbar spinal stenosis is a common degenerative condition that can cause chronic low back and leg pain, especially during walking or standing.
- Trial name
- NCT07612982
- Testing
- Ultrasound-guided lumbar interlaminar epidural steroid injection with fluoroscopic confirmation, Fluoroscopy-guided lumbar interlaminar epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Marmara University
Intubation; Difficult or Failed
Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement
This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation.
- Trial name
- NCT06656546
- Testing
- Tracheal Ultrasound, Lung Ultrasound, Diaphragm Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Stroke, Ischemic
Validation of TriAGE+ for Predicting Stroke Risk in ED Patients Presenting With Dizziness
Ischemic cerebrovascular diseases originating from the brain's posterior circulation account for 20-25% of cases. Among patients diagnosed with cerebellar infarction, 10% present with isolated dizziness as their sole symptom.
- Trial name
- NCT06641050
- Testing
- TRIAGE+ score assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Molar-Incisor Hypomineralization (MIH)
Impact of Glass-Hybrid Restoration on Occlusal Force Distribution and Masticatory Muscle Activity in Children With Molar-Incisor Hypomineralization
This prospective pilot study evaluates the effect of restoring symptomatic, carious molar-incisor hypomineralization (MIH)-affected permanent molars using a glass-hybrid restorative material on occlusal force distribution and…
- Trial name
- NCT07336212
- Testing
- Glass-Hybrid Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Marmara University
Epidural Anesthesia, Catheterisation
Epidural Catheter Placement Techniques by Anesthesia Residents: Success and Complications
This prospective observational study aims to evaluate the impact of epidural catheter placement techniques - loss of resistance (LOR) and hanging drop (HD) - on first-attempt success rates and procedural complications among…
- Conditions
- Epidural Anesthesia, Catheterisation, Education, Postoperative Pain
- Trial name
- EPİ-TECH (NCT07573007)
- Testing
- epidural catheter placement
- Where
- Turkey (Türkiye)
- Volunteers
- 440 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Frail Elderly
Comparison of the Effects of Different Exercise Protocols in Frail Elderly Individuals
The aim of this research is to investigate and compare the effects of two different exercise programs developed for frail geriatric individuals on fall risk, fear of falling, and physical performance.
- Trial name
- NCT07564076
- Testing
- Vivifrail Exercise Program, Otago Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Takayasu Arteritis (TAK), Takayasu's Arteritis
Global Initiative on Takayasu Arteritis (GITA)
Takayasu's Arteritis Global Registry aims to bring a large group of patients from different parts of the world to analyse and compare the patients' demographic, clinical, laboratory, radiological and prognostic features with…
- Trial name
- GITA (NCT07558382)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Marmara University
Carious Teeth
Clinical Efficacy of Preformed Pediatric Zirconia and Metal Crown
The study was planned to evaluate and compare the clinical success of prefabricated stainless steel crowns and zirconia crowns used in the primary molars.
- Trial name
- NCT05910905
- Testing
- Prefabricated pediatric zirconia crown group, Prefabricated stainless steel crown group
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Marmara University
Arterial Catheterization, Radial Atrery Cannulation
Proximal and Distal Radial Artery Cannulation in Children
Intraarterial cannulation is important for continuous blood pressure monitoring and blood gas analysis throughout the surgical procedure and in intensive care patients.
- Trial name
- NCT07062861
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Marmara University
Elevated Pulmonary Artery Pressure
Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure
The goal of this clinical trial is to learn if synchronous telerehabilitation is effective in patients with elevated pulmonary artery pressure identified by echocardiography (systolic pulmonary artery pressure ≥50 mmHg).
- Trial name
- NCT07535398
- Testing
- Synchronous Telerehabilitation, Breathing and Posture Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Marmara University
Breathing Exercises, PROGRESSIVE MUSCLE RELAXATION EXERCISES
THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM
This non-randomized controlled study evaluates a 10-week breathing and myofascial release program in university athletes. The intervention group receives structured training, while the control group receives only an informational…
- Conditions
- Breathing Exercises, PROGRESSIVE MUSCLE RELAXATION EXERCISES, Psychological Well-being
- Trial name
- NCT07553546
- Testing
- Integrated Breathing-Myofascial Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries, Pulpotomies Primary Teeth
Ferric Sulfate and Sodium Hypochlorite Pulpotomies in Vital Primary Teeth
This study aims to compare the clinical and radiographic success of two commonly used pulpotomy agents, ferric sulfate (FS) and sodium hypochlorite (NaOCl), in vital primary molars.
- Trial name
- NCT07548008
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
Lumbar Radiculopathy, Lumbar Disc Herniation
Treatment Response to TFESI and DRG Pulsed RF in Lumbar Spinal Stenosis and Disc Herniation
Lumbar radiculopathy caused by conditions such as lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS) can lead to chronic pain and reduced quality of life.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07509580
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University