Clinical trials: sponsored by McMaster University
Esophageal Cancer
Early Integration of Palliative Care in Esophageal Cancer Patients
Palliative care physicians and nurses are trained to help reduce suffering and improve quality of life in patients under their care.
- Trial name
- NCT02547142
- Testing
- Early Palliative Care
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McMaster University
Stroke, Comorbidity
My Stroke Team (MYST): Stroke App Pilot Study
Most stroke survivors live with other chronic health conditions that can negatively affect their recovery and overall health and well-being.
- Conditions
- Stroke, Comorbidity, Chronic Disease
- Trial name
- NCT02230280
- Testing
- Strengthening Community-Based Stroke Care: A Pilot Study of a Community Navigation and Rehabilitation Intervention that Includes a Mobile Health Solution
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Bronchiolitis, Pneumonia
Airway Pressure During Humidified High Flow Nasal Cannula Therapy in Children
Humidified High Flow Nasal Cannula (HHFNC) is a new modality of respiratory support for children with respiratory failure. Despite its extensive use in pediatric and adult population, the exact mechanism of work of HHFNC is not…
- Conditions
- Bronchiolitis, Pneumonia, Bronchial Asthma
- Trial name
- NCT02387632
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Bariatric Surgery
Deep Neuromuscular Relaxation Optimizing Low-Pressure Bariatric Surgery
This study aims to evaluate the use of deep neuromuscular blockade and low-pressure pneumoperitoneum in bariatric surgery. The investigators propose to conduct a double-blind randomized controlled trial (RCT) comparing deep…
- Trial name
- NCT03803982
- Testing
- Deep Neuromuscular Blockade, Sugammadex
- Volunteers
- 100 people
- Sponsor
- McMaster University
Covert Postoperative Stroke
Detection and Neurological Impact of CerebroVascular Events In Noncardiac Surgery PatIents: A COhort EvaluatioN
The NeuroVISION Study will characterize the incidence, impact, and risk factors of covert stroke in adults undergoing noncardiac surgery.
- Trial name
- NeuroVISION (NCT01980511)
- Where
- 11 sites in United States, Canada and 7 more
- Volunteers
- 1,116 people
- Sponsor
- McMaster University
Non-Small Cell Lung Cancer, Lung Neoplasms
McMaster Catheterization for Thoracoscopic Surgery Study
It is common practice to insert a Foley catheter into the bladder to drain urine during and after a lung resection. Recently, there has been increasing interest in the potential risks associated with this catheterization…
- Conditions
- Non-Small Cell Lung Cancer, Lung Neoplasms, Metastatic Lung Cancer, Urinary Retention
- Trial name
- UCATh (NCT02640326)
- Testing
- No Foley Urinary Catheter, Standard of care Foley urinary catheter insertion
- Where
- Canada
- Sponsor
- McMaster University
Lung Neoplasms
Does Intense Regimented Surveillance Improve the Rates of Therapeutic Re-Intervention After Lung Cancer Surgery
After curative lung cancer surgery, there is a risk of recurrence of the primary cancer, or development of a new cancer. Historically, patients who have undergone curative lung cancer surgery have been monitored with chest…
- Trial name
- Intense-CT (NCT02149576)
- Testing
- Low Dose Computed Tomography Imaging, Chest Radiograph Imaging
- Where
- Canada
- Volunteers
- 313 people
- Sponsor
- McMaster University
Stroke
Interdisciplinary Team Approach to Stroke Rehabilitation in Home Care
As the population ages and the number of stroke survivors increases, information is needed to determine the best way of providing home care services for rehabilitation to stroke survivors and their caregivers while containing…
- Trial name
- NCT00463229
- Testing
- Interprofessional Team Approach
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- McMaster University
Symptomatic Superficial Vein Thrombosis
Rivaroxaban Anticoagulation for Superficial Vein Thrombosis
This is a Phase III, randomized, placebo controlled, blinded, parallel two arm, multicentre trial that will compare rivaroxaban 10mg daily with placebo in patients with symptomatic leg Superficial Vein Thrombosis (> or = 5cm)…
- Trial name
- RASET (NCT02123524)
- Testing
- Rivaroxaban
- Where
- 11 sites in Canada
- Volunteers
- 85 people
- Sponsor
- McMaster University
Crohn Disease
Endoscopic Balloon Dilation vs Surgery to Treat Short Strictures in Fibrostenosing Crohns Disease: An RCT
There is currently no standard management to guide the clinicians in treating patients with fibrostenotic disease. European Crohns and Colitis Organization [ECCO] recently developed a topical review on prediction, diagnosis and…
- Trial name
- NCT03735355
- Testing
- Surgery, TTS balloon dilation
- Volunteers
- 40 people
- Sponsor
- McMaster University
Breast Cancer
IGAR-Breast TeleOp Trial
The aim of this study is to answer the question: can the IGAR-Breast safely and effectively perform teleoperative breast biopsies? This is a prospective, pilot trial.
- Trial name
- IGAR-Breast-TO (NCT03734432)
- Testing
- IGAR-Breast TeleOp
- Where
- 3 sites in Canada
- Volunteers
- 10 people
- Sponsor
- McMaster University
Immune System Diseases
Zoster Vaccine Response in the Frail Elderly
This study is being done to evaluate the zoster vaccine response in the nursing home elderly (80 years or older). As the immune system ages, the response to vaccines is not always as strong as in younger people.
- Trial name
- NCT01328548
- Testing
- Zostavax
- Where
- Canada
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- McMaster University
Influenza
Randomized Control Trial to Study the Efficacy of the Surgical Mask Versus the N95 Respirator to Prevent Influenza
The goal of this study is to compare the efficacy of the surgical mask to the N95 respirator in protecting nurses from influenza in the hospital setting.
- Trial name
- NCT00756574
- Testing
- Surgical mask, N95 mask
- Where
- Canada
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- McMaster University
Pneumonia, Lower Respiratory Tract Infection
A Clinical Pathway for Nursing Home Acquired Pneumonia
Nursing home residents are frequently transferred to hospital for management of pneumonia. This often leads to hospital related complications and is a burden on the acute care health system.
- Trial name
- NCT00157612
- Testing
- a clinical pathway nursing home acquired pneumonia
- Volunteers
- 680 people
- Sponsor
- McMaster University
Urinary Tract Infections
Automatic Stop Orders for Urinary Catheters
Urinary tract infections are the most common type of hospital-acquired infection. The majority of these infections result from the use of indwelling urinary catheters. Often caregivers leave them in unnecessarily.
- Trial name
- NCT00157625
- Testing
- Automatic stop order
- Where
- 3 sites in Canada
- Volunteers
- 630 people
- Sponsor
- McMaster University
Heart Failure, Influenza
Influenza Vaccine To Prevent Adverse Vascular Events (RCT-IVVE)
A multi-centre, randomized, placebo controlled, trial. Participants at high-risk for vascular events from the network of INTER- CHF will be randomized to inactivated influenza vaccine or placebo and followed prospectively over…
- Trial name
- RCT-IVVE (NCT02762851)
- Testing
- Sterile saline, inactivated trivalent influenza vaccine
- Where
- 13 sites in Cameroon, China and 11 more
- Volunteers
- 5,000 people
- Sponsor
- McMaster University
Influenza
Live Versus Inactivated Influenza Vaccine Study in Hutterite Children
There is uncertainty about whether a live attenuated vaccine (LAIV) offers additional benefit over inactivated trivalent influenza vaccine (TIV) in providing indirect benefit to those who are unvaccinated through herd immunity.
- Trial name
- NCT01653015
- Testing
- Trivalent Inactivated Vaccine, Live Attenuated Influenza Vaccine
- Where
- Canada
- Volunteers
- 4,611 people, healthy volunteers welcome
- Sponsor
- McMaster University
Pulmonary Disease, Influenza
An RCT of Oseltamivir in Outpatients With CPD: A Pilot Study.
The proposed pilot study will provide needed data to establish the feasibility of a conducting a large randomized controlled trial as to the effectiveness of the use of oseltamivir early in the course of influenza in outpatients…
- Trial name
- AVT (NCT02282384)
- Testing
- oseltamivir
- Sponsor
- McMaster University
Heart Failure
Influenza Vaccine To Prevent Adverse Vascular Events:Pilot
A multi-centre, randomized, placebo controlled, trial. Participants at high-risk for vascular events from the network of INTER- CHF will be randomized to inactivated influenza vaccine or placebo and followed prospectively over…
- Trial name
- IVVE:Pilot (NCT01945268)
- Testing
- inactivated trivalent influenza vaccine, Sterile saline
- Where
- 3 sites in Mozambique, Philippines and 1 more
- Volunteers
- 107 people
- Sponsor
- McMaster University
Influenza
Use of Probiotics to Prevent Influenza
The goal of this study is to assess the feasibility of randomizing residents of long-term care facilities to either probiotics or placebo to assess whether probiotics can reduce influenza and other viral laboratory confirmed…
- Trial name
- NCT01720329
- Testing
- Probiotics
- Where
- 13 sites in Canada
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- McMaster University