Clinical trials: sponsored by Memorial Sloan Kettering Cancer Center
Lymphoma Receiving CAR-T Therapy
Looking at Cognitive and Brain Changes in People With Lymphoma Receiving CAR-T Therapy
The purpose of this study is to learn about possible changes in cognitive (mental) abilities, such as memory skills and concentration, and in brain anatomy (structure) and function, in people with lymphoma receiving CAR-T therapy.
- Trial name
- NCT04107285
- Testing
- neurocognitive evaluations, brain MRIs, Blood samples
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Factors Associated With Breast Cancer Risks and Outcomes
The purpose of this study is to learn more about risks and outcomes of breast cancer in people with different backgrounds. Tissue and blood will be collected from participants for research purposes.
- Trial name
- NCT07294703
- Testing
- Survey
- Where
- 7 sites in United States
- Volunteers
- 750 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Intrahepatic Cholangiocarcinoma
Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery
This study will compare the safety and effects of HAI floxuridine and dexamethasone combined with the standard chemotherapy drugs gemcitabine and oxaliplatin (GemOx) with those of GemOx alone in people with untreated…
- Trial name
- NCT04891289
- Testing
- Gemcitabine, Oxaliplatin, Dexamethasone
- Where
- 11 sites in United States, Netherlands
- Volunteers
- 164 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Metastatic Renal Cell Carcinoma, Translocation Renal Cell Carcinoma
A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC)
The researchers are doing this study to find out whether the combination of abemaciclib and cabozantinib is a safe and effective treatment for people with metastatic clear cell renal cell carcinoma (ccRCC) and…
- Trial name
- NCT06835972
- Testing
- Abemaciclib, Cabozantinib
- Where
- 8 sites in United States
- Volunteers
- 43 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Metastatic Prostate Cancer
Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer
This study is to find out whether adding the study drug atezolizumab and stereotactic body radiotherapy (SBRT) to standard treatment with abiraterone acetate, prednisone, and Lupron® (leuprolide) is a safe and effective way to…
- Trial name
- NCT04262154
- Testing
- Atezolizumab, Abiraterone, Prednisone
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer Survivors
A Study of Counseling Support for Cancer Survivors Age 65+
The purpose of this study is to find out if a psychotherapy method called brief behavioral activation (BBA) can improve depression, anxiety, and overall well-being and encourage healthy lifestyle behaviors in English- and…
- Trial name
- NCT07768449
- Testing
- assessments (questionnaires)
- Where
- 7 sites in United States
- Volunteers
- 454 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Leiomyosarcoma
A Study of Ivonescimab in People With Leiomyosarcoma
The purpose of this study is to find out if Ivonescimab is an effective and safe treatment that causes few or mild side effects for people with advanced/unresectable leiomyosarcoma.
- Trial name
- NCT07516925
- Testing
- Ivonescimab
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Dedifferentiated Liposarcoma, Soft Tissue Sarcoma
A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma
Participants will have a diagnosis of dedifferentiated liposarcoma (DDLS) that has spread beyond its original location (advanced).
- Conditions
- Dedifferentiated Liposarcoma, Soft Tissue Sarcoma, Sarcoma,Soft Tissue, Sarcoma
- Trial name
- NCT05886634
- Testing
- Etrumadenant, Zimberelimab
- Where
- 7 sites in United States
- Volunteers
- 16 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Melanoma
A Study of Tumor Imaging With Multispectral Optoacoustic Tomography
Participants in this study will have Multispectral Optoacoustic Tomography/MSOT imaging of both breasts immediately before their ultrasound-guided breast biopsy procedure begins.
- Trial name
- NCT05488483
- Testing
- Multispectral Optoacoustic Tomography Imaging
- Where
- 4 sites in United States, Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neuroendocrine Cancer, Small Cell Lung Cancer
A Study of Armored CAR T Cells in People With Cancer
The purpose of this study is to test the safety of DLL3-SAVVYZ-IL18 in people with DLL3+ cancer.
- Conditions
- Neuroendocrine Cancer, Small Cell Lung Cancer, Small Cell Lung Cancer ( SCLC )
- Trial name
- NCT07783477
- Testing
- DLL3-SAVVYZ-IL18 CAR T cell
- Where
- 7 sites in United States
- Volunteers
- 16 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Malignant Melanoma of Skin, Other and Unspecified Malignant Neoplasm of Skin
Using an Artificial Intelligence (AI) Tool for Melanoma Diagnosis
The purpose of this study is to learn whether a computer-based support tool called DEXI (Dermoscopy EXplainable Intelligence) can help dermatologists decide whether a lesion may be melanoma, a serious type of skin cancer.
- Conditions
- Malignant Melanoma of Skin, Other and Unspecified Malignant Neoplasm of Skin, Melanoma in Situ, Carcinoma in Situ of Skin
- Trial name
- NCT07890415
- Testing
- Clinical decision support tool
- Where
- 8 sites in United States
- Volunteers
- 14,000 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
NK/T-Cell Lymphoma of Nasal Cavity (Diagnosis), NK/T-Cell Lymphoma of Nasopharynx (Diagnosis)
Study of Pembrolizumab in Patients With Early-Stage NK/T-cell Lymphoma, Nasal Type
The purpose of this study is to test how well pembrolizumab shrinks Early-Stage NK/T-cell Lymphoma (ENKTL) in participants who have not yet received chemotherapy.
- Trial name
- NCT03728972
- Testing
- Pembrolizumab
- Where
- 10 sites in United States
- Volunteers
- 19 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lymphoma, Relapsed
Combination Therapy With Entinostat and Pembrolizumab in Relapsed and Refractory Lymphomas
The purpose of this study is to test any good and bad effects of the study drugs called Pembrolizumab and Entinostat when used in combination to treat lymphoma.
- Conditions
- Lymphoma, Relapsed, Refractory
- Trial name
- NCT03179930
- Testing
- Entinostat, Pembrolizumab
- Where
- 9 sites in United States
- Volunteers
- 47 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Endometrial Cancer
A Study of a Weight Loss Intervention in People With Endometrial Cancer
The researchers are doing this study is to find out whether tirzepatide and semaglutide are practical (feasible) for weight management and blood sugar control for endometrial cancer patients undergoing chemotherapy.
- Trial name
- NCT06751589
- Testing
- Tirzepatide
- Where
- 7 sites in United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Non-Small Cell Lung Cancer, Non-small Cell Lung Cancer Stage II
A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer
The purpose of this study is to find out how many people with HER2-amplified or HER2-mutated non-small cell lung cancer (NSCLC) experience a decrease in tumor viability when they receive trastuzumab deruxtecan before routine…
- Conditions
- Non-Small Cell Lung Cancer, Non-small Cell Lung Cancer Stage II, Non-Small Cell Lung Cancer Stage IIIA, Non-Small Cell Lung Cancer Stage IIIB
- Trial name
- NCT07428044
- Testing
- Trastuzumab Deruxtecan
- Where
- 10 sites in United States, Canada
- Sponsor
- Memorial Sloan Kettering Cancer Center
Head and Neck Cancer, Head and Neck Tumor
A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer
The overarching long-term goal of the Integrative Medicine for Patient-reported Outcomes Values and Experience (IMPROVE) research program is to evaluate whether integrating a virtual mind-body programming, Integrative Medicine at…
- Conditions
- Head and Neck Cancer, Head and Neck Tumor, Thoracic Tumor, Thoracic Cancer
- Trial name
- IMPROVE (NCT05053230)
- Testing
- IM@Home, Enhanced usual care
- Where
- 7 sites in United States
- Volunteers
- 324 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Leukemia, Acute Leukemia
A Study of Revumenib and Mezigdomide in People With Leukemia
The purpose of this study is to find out whether the combination of mezigdomide and revumenib is a safe treatment for people with relapsed or refractory KMT2A-r, NUP98-r, and NPM1-m acute leukemias.
- Conditions
- Leukemia, Acute Leukemia, Relapse Leukemia, Refractory Leukemia
- Trial name
- NCT07356154
- Testing
- Revumenib, Mezigdomide
- Where
- 10 sites in United States
- Volunteers
- 52 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer
This is a phase l/II study. The purpose of this study is to test the safety of the study drug neratinib in combination with a standard chemotherapy drug called capecitabine at different doses to find out what effects, if any, it…
- Trial name
- NCT03377387
- Testing
- Capecitabine, Neratinib, EORTC QLQ - BR23, EQ-5D-5L, EORTC QLQ-C30
- Where
- 10 sites in United States
- Volunteers
- 34 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Vaping
Study of Vaping Use Among Adolescent and Young Adult Patients With Cancer
The purpose of this study is to learn more about how adolescent and young adult (AYA) cancer patients, their parents and caregivers (referred to as a carebuddy in this study), and their healthcare providers think about and…
- Trial name
- NCT07860801
- Testing
- Study assessments
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Breast Cancer Female
Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)
The purpose of this study is to train Nigerian radiologists to perform ultrasound-guided breast biopsies. Researchers will use mHealth devices to create a sustainable and practical way of training radiologists in Nigeria to…
- Trial name
- NCT05561842
- Testing
- mHealth US-breast biopsy
- Where
- 8 sites in United States, Nigeria
- Volunteers
- 900 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.