Clinical trials: sponsored by Menoufia University
Post Operative Analgesia
Intravenous Ibuprofen Postoperative Analgesia After Abdominal Hysterectomy
The current research is designed to investigate the analgesic efficacy of intravenous ibuprofen on the postoperative analgesic requirements, pain intensity and other recovery parameters.
- Trial name
- NCT05750264
- Testing
- Ibuprofen
- Where
- Egypt
- Volunteers
- 152 people
- Sponsor
- Menoufia University
Edentulism Complete
Accuracy of Complete-Arch Implant Scans Using Non Calibrated Splinting Scanbodies
This randomized crossover clinical study will evaluate and compare the accuracy and chairside time of two non-calibrated splinting systems, IoConnect and Scan Pro, for obtaining complete-arch implant digital scans.
- Trial name
- NCT07862218
- Testing
- Scan Pro, IoConnect
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Menoufia University
Edentulism in Lower Jaw
Accuracy of Immediate Implant Placement
This randomized clinical study will compare the accuracy of immediate implant placement performed using three different surgical approaches: freehand surgery, conventional tooth-supported static computer-guided surgery, and a…
- Trial name
- NCT07863700
- Testing
- Freehand Immediate Implant Placement, Tooth-Supported Static Computer-Guided Implant Placement, Tooth- and Socket-Supported Static Guided Implant Placement
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Anatomical Distal Fibular Plate, Conservative Treatment
Anatomical Distal Fibular Plate and Conservative Treatment in Management of Infrasyndesmotic Fibular Fracture
The aim of this study is to evaluate the functional and radiological outcome of treatment of infrasyndesmotic distal fibula fracture by operative management by anatomical distal fibular plate vs conservative treatment and to…
- Conditions
- Anatomical Distal Fibular Plate, Conservative Treatment, Infrasyndesmotic Fibular Fracture
- Trial name
- NCT07872540
- Testing
- Anatomical distal fibular plate., Conservative treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Menoufia University
Breast Cancer, Radiotherapy Induced Fatigue
Efficacy of High-Dose Melatonin in Alleviating Radiotherapy-Induced Fatigue in Breast Cancer Patients
To assess the role of High-Dose Melatonin in Alleviating Radiotherapy-Induced Fatigue in Breast Cancer Patients. The primary end point is assessment of fatigue severity .
- Trial name
- NCT07865988
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Menoufia University
Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries
Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per…
- Trial name
- NCT07853586
- Testing
- ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Cesarean Section, Spinal Anesthesia
Low Dose Hyperbaric Bupivacaine and Dexmedetomidine as an Adjuvant, Caesarean Section
The aim of this study is to evaluate the effectiveness of low dose scheme with dexmedetomidine as an adjuvant. Taking in consideration optimum intraoperative surgical conditions, best post-operative pain free experience, and more…
- Conditions
- Cesarean Section, Spinal Anesthesia, Dexmedetomidine
- Trial name
- NCT03775655
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Treatment of Non-monosymptomatic Nocturnal Enuresis
Efficacy of Mirabegron for Treatment of Non-monosymptomatic Nocturnal Enuresis in Children
This phase 3 clinical trial will compare use of individual treatment with mirabegron or desmopressin and their combination for treatment of non-monosymptomatic nocturnal enuresis in children
- Trial name
- NCT07398261
- Testing
- Mirabegron 25 MG
- Where
- Egypt
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Severe Sepsis
Plasma Exchange in Children With Severe Sepsis and Septic Shock
The aim of the study will be to to evaluate whether therapeutic plasma exchange (TPE) reduces mortality in critically ill children with severe sepsis or septic shock compared to the standard care of sepsis alone.
- Trial name
- PE/Sepsis (NCT07706413)
- Testing
- Plasma exchange (PE)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Menoufia University
Urethral Stricture, Anterior, Urethral Stricture Disease
Outcomes of Double-face Augmentation Urethroplasty
Combined dorsal and ventral onlay augmentation for bul¬bar urethral reconstruction. Nontraumatic near-obliterative bulbar urethral strictures (BUS) of <2 cm in length can be managed with non-transecting anastomotic bulbar…
- Trial name
- BMG (NCT07436819)
- Testing
- Double-face augmentation urethroplasty
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Menoufia University
Autoimmune Encephalitis (AE)
Plasma Exchange in Pediatric Autoimmune Encephalitis
The aim of the study will be to compare the efficacy of daily plasma exchange (PLEX) versus alternate-day PLEX in achieving a favorable functional outcome in children with autoimmune encephalitis.
- Trial name
- PE/AIE (NCT07707739)
- Testing
- Plasma exchange (PE)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Menoufia University
Prophylactic, Anticoagulation
Prophylactic Anticoagulation for Central Venous Line Insertion in Critically Ill Children
This will be a Prospective, randomized, open- label, parallel-group, center trial, which will include 80 of Children which will be admitted at Pediatric Intensive Care Unit (PICU) of Menoufia university Hospital from August 2026…
- Trial name
- NCT07710482
- Testing
- Enoxaparin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Sepsis and Septic Shock
Dynamic SvO2 in Predicting Fluid Responsiveness in Septic Shock
This prospective observational diagnostic accuracy study investigates the efficacy of dynamic central venous oxygen saturation in predicting fluid responsiveness in septic shock, compared to measurements obtained using…
- Trial name
- NCT07516236
- Testing
- Measuring dynamic central venous oxygen saturation (ScvO2) at baseline and after fluid challenge. Measuring Cardiac output by echocardiography or cardiometry at baseline and after fluid challenge.
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Menoufia University
Liver Resection, Upper Abdominal Surgeries
Comparative Effects of ESP Block and EOIP Block on Postoperative Respiratory Recovery Following Liver Resection
This study evaluates respiratory recovery as a multidimensional construct using clinically relevant and measurable parameters, including LUS, diaphragmatic excursion, oxygen requirement, and PPCs.
- Trial name
- NCT07740382
- Testing
- Ultrasound-guided bilateral external oblique intercostal plane (EOIP) block, Ultrasound-guided bilateral erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Menoufia University
Quadratus Lumborum Block, Transversus Abdominis Plane Block
Quadratus Lumborum Block, Transversus Abdominis Plane Block, and Erector Spinae Block in Pediatric Abdominal Surgery
The aim of this study is to compare the analgesic efficacy and safety of Quadratus Lumborum (QL), Transversus Abdominis Plane (TAP), and Erector Spinae Plane (ESP) blocks in pediatric abdominal surgery.
- Conditions
- Quadratus Lumborum Block, Transversus Abdominis Plane Block, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07850596
- Testing
- Quadratus lumborum (QL) block, Transversus abdominis plane (TAP) block, Erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Thyroid Surgeries
Comparative Study of Ultrasound Guided Superficial vs Intermediate Cervical Plexus Block for Perioperative Analgesia in Thyroid Surgeries.
The investigator compare the analgesic efficacy of ultrasound-guided subcutaneous cervical plexus block vs ultrasound-guided intermediate cervical plexus block pre-intra and postoperative thyroid surgery
- Trial name
- NCT07843589
- Testing
- Ultrasound guided superficial cervical plexus block, ultrasound guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Cervical, Erector Spinae Plane Block
Cervical Erector Spinae Plane Block in Proximal Humeral Fracture Surgery, A Motor-Sparing Block
This study aims to evaluate the efficacy of cervical erector spinae plane block (ESPB) in managing postoperative pain following proximal humerus fracture repair in patients receiving general anesthesia.
- Conditions
- Cervical, Erector Spinae Plane Block, Proximal Humeral Fracture Surgery
- Trial name
- NCT07824466
- Testing
- Cervical erector spinae plane block, General anesthesia
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Menoufia University
Edentulous Jaw
Accuracy of Complete-Arch Implant Photogrammetry
This prospective comparative clinical study evaluated the accuracy and chairside time of complete-arch implant scans obtained using an intraoral photogrammetry system and a mobile-phone-based photogrammetry system in edentulous…
- Trial name
- NCT07643441
- Testing
- Intraoral Photogrammetry (IPG), Mobile-Phone-Based Photogrammetry
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Menoufia University
Edentulous Jaw
Accuracy of Complete-arch Implant Scans Obtained Using T-Marker
This randomized crossover clinical study will evaluate and compare the accuracy and effective scanning time of complete-arch implant scans obtained using the (TruAbutment,Marker) T-Marker photogrammetry application operated on a…
- Trial name
- NCT07821905
- Testing
- Smartphone, Tablet
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Menoufia University
Obese Patients
External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery
Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing…
- Trial name
- NCT07809425
- Testing
- Investigatore hypothesize that adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption., Bilateral EOIB + fentanyl 1 μg/kg loading + normal saline loading (equivalent volume) + normal saline infusion (equivalent rate).
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University