Clinical trials: sponsored by Menoufia University
Critically Ill Intensive Care Unit Patients
Diagnostic Accuracy of Hepatic Vein SFF Compared With TAPSE for Assessment of RV Systolic Function in Mechanically Ventilated Patients
This prospective observational diagnostic accuracy study investigates the efficacy of the hepatic vein systolic filling fraction (SFF) as a real-time, non-invasive indicator of right ventricular (RV) systolic function in…
- Trial name
- NCT07732114
- Testing
- Diagnostic accuracy of hepatic vein systolic filling fraction compared with TAPSE for assessment of right ventricular systolic function in mechanically ventilated critically ill patients
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Menoufia University
Edentulism, Edentulism Complete
Comparison of Non-Calibrated Splinting Bodies and T-Marker for Complete-Arch Implant Scanning
This randomized crossover clinical trial aims to compare the accuracy and scanning efficiency of two digital techniques for recording implant positions in completely edentulous patients receiving implant-supported full-arch…
- Trial name
- NCT07723404
- Testing
- Non-Calibrated Splinting Scan Body System (IoConnect), Mobile Phone-Based Photogrammetry System (T-Marker)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Tooth Loss
Digitally Assisted Immediate Implants in Geriatric Patients
This prospective clinical study aims to evaluate the clinical performance of digitally assisted immediate implant placement and immediate loading in geriatric patients.
- Trial name
- NCT07534514
- Testing
- Digitally Assisted Immediate Implant Placement and Immediate Loading
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Erectile Dysfunction
Efficacy of Transcutaneous Electrical Neural Stimulation and Tadalafil in Men With Erectile Dysfunction: A Randomized, Double-Blind, Bi-centric, Placebo- and Sham-Controlled Trial
Organic erectile failure is thought to be caused predominantly by neurogenic or vascular disorders. Venoocclusive dysfunction of the corpora cavernosa induces erectile dysfunction in 20-30% and appears clinically by premature…
- Trial name
- NCT07574268
- Testing
- Placabo, Tadalafil 5 mg, Active TENS
- Where
- Egypt
- Volunteers
- 185 people
- Sponsor
- Menoufia University
Mucormycosis
Rehabilitation With an Obturator in Maxillary Defects
During the COVID-19 pandemic, there was a lot of reporting of COVID-19-associated mucormycosis cases. Managing this condition posed a new challenge to clinicians.
- Trial name
- NCT06515743
- Testing
- Obturator Prosthetic Rehabilitation
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Menoufia University
Postoperative Delirium
Dexmetomedine for Post Operative Delirium in Elderly Patients Undergoing Elective Total Knee Replacement Under Spinal Anesthesia
Postoperative delirium is a geriatric syndrome occurring after anesthesia and surgery which manifests as acute alterations in mental status, involving changes in cognition, attention, and levels of consciousness that tend to…
- Trial name
- NCT05707741
- Testing
- dexmetomedine infusion
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Chronic Post Cesarean Pain
Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section
The aim of this study is to compare the incidence of CPSCP in patients receiving QLB quadratus lumborum block and ITM versus control as a primary outcome and associated risk factors that might predispose patients to develop CPSCP.
- Trial name
- NCT05602038
- Testing
- Quadratus laborum block, Intrathecal morphine, intrathecal bupivacaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Total Dose of Bupivacaine Administered During Labor
Dexmedetomidine as an Adjuvant During Dural Puncture Epidural
The study aimed to determine the effects of using varied doses of DEX on the concentration of bupivacaine injected for epidural labor analgesia, and to assess the benefits of the dural puncture epidural.
- Trial name
- NCT07506044
- Testing
- Epidural Catheter with bupivacaine, Epidural with dural puncture, Dexmedetomidine 0.4 added
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Menoufia University
Change in Serum Levels of the Estimated Inflammatory Cytokines, Total Dose of IO Fentanyl
Deep Versus Moderate Neuromuscular Blocking
This study aimed for Determination of the impacts of deep neuromuscular blockade (DNMB) on surgical outcomes, consumption of perioperative opioid analgesia, and serum levels of inflammatory cytokines in comparison to moderate NMB…
- Conditions
- Change in Serum Levels of the Estimated Inflammatory Cytokines, Total Dose of IO Fentanyl, PO Morphine, Surgeons' Rating
- Trial name
- NCT07485517
- Testing
- Moderate Neuromuscular Blockade, Deep neuromuscular block
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Menoufia University
Initial Caries
Early Detection of Initial Caries Using Fluorescent Starch Nano-particles Compared With Salivary Biomarkers
Dental caries is one of the most prevalent chronic oral diseases worldwide and remains a major public health concern. The disease begins with microscopic demineralization of enamel, which is reversible if diagnosed at an early…
- Trial name
- NCT07732127
- Testing
- Fluorescent Starch Nano-particles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Congenital Hypothyroidism
Levothyroxine Dosing in Neonatal Congenital Hypothyroidism
This randomized controlled trial compared high-dose and moderate-dose levothyroxine as initial therapy for neonates with primary congenital hypothyroidism.
- Trial name
- CH-LT4 (NCT07754370)
- Testing
- Levothyroxine
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Menoufia University
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Denture, CAD/CAM
Effect of Certain Denture Disinfectants on Surface Topography, Microhardness and Dimensional Stability of CAD/CAM Milled Polymethyl Methacrylate and Polyether Ether Ketone Denture Base Materials
This study aims to evaluate and compare the influence of different denture cleansing methods using 1% sodium hypochlorite solution, 0.2% chlorhexidine solution and effervescent alkaline peroxide tablet solution -according to…
- Conditions
- Denture, CAD/CAM, Stability, PEEK
- Trial name
- NCT07672847
- Testing
- M0 group, M1 group : PMMA+ Sodium hypochlorite, M2 group: PMMA+ Chlorhexidine
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Menoufia University
Hemidiaphragmatic Paralysis, Postoperative Pain
Comparative Evaluation of Diaphragmatic Function Following Interscalene, Anterior Suprascapular, and Costoclavicular Nerve Blocks in Shoulder Surgery
Shoulder surgery causes significant postoperative pain, and ultrasound-guided regional anesthesia is central to its management. The interscalene block (ISB) is the gold standard but frequently causes phrenic nerve paralysis and…
- Conditions
- Hemidiaphragmatic Paralysis, Postoperative Pain, Shoulder Surgery, Brachial Plexus Block
- Trial name
- NCT07671352
- Testing
- Ultrasound-guided interscalene brachial plexus block, Ultrasound-guided suprascapular nerve block, Ultrasound-guided costoclavicular brachial plexus block
- Volunteers
- 75 people
- Sponsor
- Menoufia University
Labor Pain
Color Doppler to Confirm Epidural Catheter Positioning in Parturient
The aim of this study is to calculate the sensitivity and specificity of using color Doppler with pulsed wave Doppler to accurately detect the position of epidural catheter
- Trial name
- NCT05606952
- Testing
- Color Doppler
- Where
- Egypt
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bipolar Disorder, Caregiver Burden
Psychiatric Nursing Intervention for Caregivers of Patients With Bipolar Disorder
This study aims to evaluate the effectiveness of an innovative psychiatric nursing intervention in reducing caregiver burden and enhancing psychological resilience and positive emotional outcomes among family caregivers of…
- Conditions
- Bipolar Disorder, Caregiver Burden, Psychological Resilience
- Trial name
- BD-Care (NCT07548359)
- Testing
- Psychiatric Nursing Intervention
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Prosthesis User
Clinical Performance of 3D-Printed Resin and Zirconia Implant Restorations
This randomized controlled clinical trial evaluates the clinical performance of 3D-printed resin restorations compared with milled monolithic zirconia in implant-supported single crowns and short-span fixed partial dentures…
- Trial name
- NCT07522671
- Testing
- 3D-Printed Resin Restoration (CROWNTEC)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Preeclampsia
Assessment of Volume Status in Preeclampsia Post- SpinalAnasthesia:Utilizing Ultrasound " Evaluation of Lung and Inferior Vena Cava"
Primary aim Assess the accuracy and reliability of ultrasound evaluation of lung and inferior vena cava in determining volume status post-spinal anesthesia in pre-eclampsia patients.
- Trial name
- AComparative (NCT07514130)
- Testing
- Ultrasound lung, ultrasound for IVC diameter, Intrathecal bupivacane
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Menoufia University
Time
Perioperative Analgesic Effect of Different Volumes of Modified Thoracoabdominal Perichondrial Approach on Patients Undergoing Sleeve Gastrectomy: Prospective Randomized Trial
Sleeve gastrectomy is a leading technique in metabolic \& bariatric surgery. It gained ever-increasing popularity among laparoscopic bariatric surgeries and has proved to be a successful method in achieving considerable weight…
- Trial name
- NCT07510347
- Testing
- Modified Thoracoabdominal Nerve Block through perichondrial approach (M-TAPA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Analgesia
Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery
Whether trans muscular QLB provides postoperative analgesia compared with LPB after thigh lift surgery
- Trial name
- QLB&LPB (NCT07280182)
- Testing
- Ultrasound-Guided Trans-muscular QLB, Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Menoufia University