Clinical trials: sponsored by Menoufia University
Post Operative Pain
Bupivacaine With Dexmedetomidine Versus Bupivacaine Alone for Transversus Abdominis Plane Block in Caesarean Section
Transversus Abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic…
- Trial name
- NCT06292273
- Testing
- Transversus Abdominis Plane Block with bupivacain Plus dexamethasone, Transversus Abdominis Plane Block with bupivacain
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Ketamine, Propofol
Ketamine Versus Propofol as ICU Sedation
this study is to assess the hemodynamic profile of ketamine compared with propofol in critically ill, mechanically ventilated adult Patients study will be carried out on 100 mechanically ventilated patients who received one…
- Conditions
- Ketamine, Propofol, Sedation, Mechanical Ventilation
- Trial name
- NCT06243822
- Testing
- Ketamine, Propofol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Locally Advanced Breast Cancer, Intermittent Fasting
Influence of Intermittent Fasting on Locally Advanced Breast Cancer Patients
Breast cancer is the most common cancer type among women in Egypt and world. Preclinical studies show fasting reduces growth factors and modulates nutrient sensing systems, protecting normal cells against chemotherapy.
- Trial name
- NCT06174259
- Testing
- intermittent fasting
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Menoufia University
Post Operative Pain
Dexmetomedine as an Adjuvant to Bupivacaine in Ultrasound Guided PECS Block
Regional anesthesia is an essential component of anesthesia and analgesia. It has many advantages, it decreases pain post operatively, improves patient outcome and allow early recovery and ambulation Post-operative pain following…
- Trial name
- NCT05717114
- Testing
- Pecs block
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Stomach Cancer, Gastric Cancer
Docetaxel and Irinotecan in Gastric Cancer
To assess the role of docetaxel and irinotecan combination in second line gastric cancer. The primary end point is response rate. Secondary end points are toxicity, PFS and OS.
- Conditions
- Stomach Cancer, Gastric Cancer, Chemotherapy Effect
- Trial name
- NCT04770623
- Testing
- Docetaxel, Irinotecan
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Menoufia University
Opioid Use
Two Approaches of Transversus Abdominis Block (TAP ) in Laparoscopic Cholecystectomy
the investigators will compare the effect of pre-operative oblique subcostal TAP and lateral TAP blocks on the total perioperative opioids consumption for patients undergoing elective laparoscopic cholecystectomy
- Trial name
- TAP (NCT05946733)
- Testing
- Group A, Group B, Group C
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Post Operative Pain
Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy
The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive U S guided external oblique intercostal block after induction.
- Trial name
- EOINBvsESB (NCT06048744)
- Testing
- external oblique intercostal block, Erector Spine block
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Menoufia University
Carpal Tunnel Syndrome
Study of Single Platelet-Rich Plasma Local Injection Vs. Single Corticosteroid Local Injection in Carpal Tunnel Syndrome
This clinical trial aims to evaluate the effect of a single local platelet-rich plasma injection Versus local steroid injection in treating mild idiopathic carpal tunnel syndrome regarding pain relief and function improvement and…
- Trial name
- NCT06209957
- Testing
- Local corticosteroid injection, Platelet-rich Plasma Local injection
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Preterm Birth
Comparative Study Between Vaginal Progesterone Alone or Combined With Aspirin in Prevention of Recurrent Preterm Birth
This is a double blinded randomized placebo controlled clinical trial to detect the efficacy and safety of vaginal progesterone alone or combined with aspirin in prevention of recurrent PTB.
- Trial name
- prematurity (NCT05319834)
- Testing
- Aspirin tablet
- Where
- Egypt
- Volunteers
- 256 people
- Sponsor
- Menoufia University
Analgesia
Ultrasound Guided Block for Postoperative Analgesia in Arthroscopic Shoulder Surgery
This study aimed to compare the efficacy of high thoracic-ESPB with shoulder block as analgesic options for arthroscopic shoulder surgery. Primary outcome: 24-hour analgesic consumption.
- Trial name
- NCT06202430
- Testing
- High Thoracic Erector Spinae Plane Block, Shoulder Block
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bipolar TURP , Laser Enucleation in Management of Enlarged Prostate
Bipolar Versus Laser Enaculation of Prostate for >80gram Prostate .
Transurethral resection of the prostate (TURP ) still the gold standerad for surgical management of enlarged prostate .However , many minimally invasive procedures are now in the comparative track with Bipolar resection as Laser…
- Trial name
- NCT05784181
- Testing
- bipolar transurethral resection and Laser enaculation by holmium: YAG laser
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block (PENG Block)
Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.
- Trial name
- NCT05930171
- Testing
- Ultrasound guided L-ESPB and PENG block using Bupivacaine, Postoperative conventional analgesia in form of Acetaminophen
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Postoperative Pain
Epidural Catheter and Surgically Implanted Rectus Sheath Catheter in Management of Postoperative Pain
One hundred and twenty patients at age range from 18 to 60 undergoing laparotomy was enrolled in this study. Patients were randomly assigned to two groups 60 in epidural group and the other 60 patients in rectus catheter group.
- Trial name
- NCT04755725
- Testing
- Epidural catheter, rectus sheath catheter
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Menoufia University
Postoperative Pain
Depomedrol for Genicular Nerve Block.
This study is designed to test the efficacy of adding Depomedrol a long-acting steroid to bupivacaine for relieving postoperative pain and reducing opioid requirements following total knee replacement surgery.
- Trial name
- NCT05893771
- Testing
- Methylprednisolone Injection, Bupivacaine Hcl 0.5% Inj_#2, normal saline
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Menoufia University
Ventilator Associated Pneumonia
Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia
It has been shown that oral hygiene reduces the incidence of ventilator-associated pneumonia (VAP). The nasopharynx is considered to be an important source of contaminated micro aspiration to the lung however, the effect of…
- Trial name
- NCT05895773
- Testing
- Povidone-Iodine, Saline spray
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Menoufia University
Sugammadex, Neostigmine
Neostigmine Versus Sugammadex on Renal Functions
The study will assess the acute effects of sugammadex or neostigmine on renal function as determined with more specific and sensitive tests in laparoscopic cholecystectomy
- Trial name
- NCT06081738
- Testing
- Neostigmine, Sugammadex
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Emergence Agitation
Melatonin for Pediatric Emergence Agitation
efficacy of melatonin premedication on emergence agitation in children undergoing herniorrhaphy surgeries
- Trial name
- NCT05223010
- Testing
- Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg
- Where
- Egypt
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bladder Cancer
Validity of Computed Tomography Versus Magnetic Resonance Imaging in Predicting Muscular Invasion of Bladder Cancer
The aim of this work is to compare validity between CT and MRI in detecting muscular invasion in Patients with bladder cancer.
- Trial name
- NCT06046469
- Testing
- CT with contrast, MRI pelvis, TURBT
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Menoufia University
Delirium in Old Age
Melatonin for Post Operative Delirium Prevention in Elderly Patients
The present study will evaluate the role of melatonin prophylaxis in delirium prevention in elderly patients undergoing colorectal procedures.
- Trial name
- NCT05640934
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Hemodynamic Responses, Laparoscopic Cholecystectomy
Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy
This study will be carried out to compare the efficacy of dexmedetomidine, propofol or lidocaine infusions in attenuation of hemodynamic responses to pneumoperitoneum during adult laparoscopic cholecystectomy using electrical…
- Conditions
- Hemodynamic Responses, Laparoscopic Cholecystectomy, Dexmedetomidine, Lidocaine
- Trial name
- NCT05937282
- Testing
- Dexmedetomidine, Propofol, Lidocain
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University