Clinical trials: active, sponsored by Minia University
Postoperative Pain
Clinical Efficacy of a Natural Biopolymer-Based Irrigant
One primary objective in the root canal treatments is to ensure chemo mechanical removal of microorganisms and organic/inorganic tissue residues from the infected root canals.
- Trial name
- NCT07901127
- Testing
- Chitosan Nanoparticles
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Minia University
Periapical Healing
Evaluation of Three Different Intra-canal Medicaments
Periapical lesions are the commonly occurring pathologic lesions that affect the periradicular tissues of the tooth . This lesion can be classified as granuloma, cystic, or abscess .The pathologic changes seen in some…
- Trial name
- NCT07892703
- Testing
- Metapaste Calcium Hydroxide
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Minia University
Chronic Apical Periodontitis
Effect of Cyperus Articulatus on Bacterial Reduction and Postoperative Pain
Successful endodontic treatment depends on effective elimination of microorganisms from the infected root canal system and prevention of reinfection.
- Trial name
- NCT07892690
- Testing
- Cyperus articulatus
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Difficult Airway Management
Prediction of Difficult Mask Ventilation in Obese Population Undergoing Emergency Surgery
The current study is an observational, prospective study. It will be conducted in the emergency operative theatre, Alfayoum University, Alfayoum, Egypt.
- Trial name
- NCT07887503
- Volunteers
- 550 people
- Sponsor
- Minia University
Ventilator-associated Pneumonia, Traumatic Brain Injury
Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury
This randomized controlled trial will compare closed versus open endotracheal suctioning techniques for preventing ventilator-associated pneumonia (VAP) in adults with severe traumatic brain injury (TBI) who need mechanical…
- Trial name
- NCT07883083
- Testing
- Closed endotracheal suction system, Open endotracheal suction
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Minia University
Postoperative Analgesia in Patients Undergoing Open Renal Surgery
Ultrasound-Guided Midpoint Transverse Process to Pleura Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Open Renal Surgery :A Randomized Comparative Study.
The goal of this randomized comparative clinical trial is to compare the analgesic effectiveness of ultrasound-guided Midpoint Transverse Process to Pleura (MTP) block versus Erector Spinae Plane (ESP) block in adult patients…
- Trial name
- NCT07881523
- Testing
- Midpoint Transverse Process to Pleura (MTP)Block, Erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Postoperative Pain, Middle Ear Surgery
Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear Surgeries
This randomized, double-blind, controlled study will evaluate whether adding dexmedetomidine to bupivacaine in an ultrasound-guided greater auricular nerve block prolongs pain relief after middle ear surgery.
- Trial name
- NCT07878533
- Testing
- Bupivacaine, Dexmedetomidine, Normal saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Tooth Discoloration, Tooth Staining
Peroxide Versus Non-Peroxide In-Office Tooth Bleaching
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems.
- Trial name
- BECTS (NCT07818031)
- Testing
- peroxide -based in office tooth bleaching, non-peroxide -based in office tooth bleaching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Post Operative Pain, Thoracic Surgery
Comparative Study Between Erector Spinae Plane Block Versus Combined Pectoralis and Serratus Interfascial Plane Blocks for Post-operative Analgesia After Thoracic Surgery.
The aim of this study is to evaluate the effect of combined pectoralis II and serratus interfascial plane blocks in comparison with erector spinae plane block on post-operative analgesia after thoracic surgeries.
- Trial name
- NCT07855549
- Testing
- Erector spinae plane block, Combined pectoralis and serratus anterior plane blocks
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Minia University
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University
TEETH EXTRACTION, Esthetic Zone Implantology
Guided Root Slice Replantation vs. Socket Shielding for Immediate Implant Placement in Esthetic Zone
The goal of this clinical trial is to learn whether two different tooth-preservation techniques work equally well when placing a dental implant right after a tooth is removed in the front of the mouth (the "esthetic zone").
- Conditions
- TEETH EXTRACTION, Esthetic Zone Implantology, Socket Shield Technique Implant Placement, Root Slicing
- Trial name
- NCT07845019
- Testing
- Guided socket shield with immediate implant, Guided Autogenous Root Slicing Replantation with Immediate Implant, Conventional Bone Augmentation with Immediate Implant
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Esophageal Achalasia, Esophageal Motility Disorders
POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia
Achalasia is a disorder of the esophagus in which the muscular valve between the esophagus and the stomach fails to relax, and the body of the esophagus loses its normal coordinated squeezing movement.
- Conditions
- Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux
- Trial name
- POEM-HD (NCT07814027)
- Testing
- Peroral endoscopic myotomy, Laparoscopic Heller myotomy with Dor fundoplication
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Minia University
Gastroesophageal Reflux Disease, Hiatal Hernia
Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication
Laparoscopic fundoplication is the standard operation for gastroesophageal reflux disease (GERD) that does not respond adequately to medication, and it relieves reflux symptoms in most patients who are carefully selected for it.
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Esophagitis, Peptic, Barrett Esophagus
- Trial name
- NCT07809620
- Testing
- Laparoscopic Nissen fundoplication, Laparoscopic Toupet fundoplication
- Where
- Egypt
- Volunteers
- 470 people
- Sponsor
- Minia University
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer
Mesopancreatic Excision for Pancreatic Duct Adenocarcinoma.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with high rates of local recurrence and distant metastasis. Recent evidence suggests that mesopancreatic excision (TMpE) may improve R0 resection rates, reduce local…
- Trial name
- TMpE (NCT07148830)
- Testing
- Total Mesopancreas Excision (TMpE) (as part of Pancreaticoduodenectomy)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Pancreas Cancer, Periampullary Cancer
Neoadjuvant vs Upfront Surgery for Resectable Pancreatic Cancer and Periampullary Cancer
Adjuvant chemotherapy after surgery significantly improved the survival of pancreatic cancer (PC) patients, but there is a problem that only about 50% of patients start adjuvant chemotherapy after pancreatectomy.
- Conditions
- Pancreas Cancer, Periampullary Cancer, Periampullary Carcinoma Resectable, Pancreatic Cancer Resectable
- Trial name
- NCT07081360
- Testing
- Neoadjuvant chemotherapy, Upfront Surgery Group
- Where
- Egypt
- Volunteers
- 262 people
- Sponsor
- Minia University
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
This study investigates the safety and efficacy of injecting N-butyl-2-cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the pancreaticojejunostomy (PJ)…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07132541)
- Testing
- Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Bacterial Keratitis, Recalcitrant Infectious Keratitis
Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis
Bacterial keratitis is a potentially sight-threatening corneal infection that is commonly treated with intensive topical antibiotics.
- Conditions
- Bacterial Keratitis, Recalcitrant Infectious Keratitis, Corneal Ulcer
- Trial name
- NCT07394257
- Testing
- Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy, Standard topical moxifloxacin therapy alone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Postoperative Pain, Irreversible Pulpitis
Impact of Cross-Sectional Design in Single-File Rotary System on Apical Debris Extrusion
Endodontic treatment aims to achieve optimal biological outcomes while minimizing patient's discomfort during and after the procedure.
- Trial name
- NCT07808684
- Testing
- AF One single-file rotary system
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University