Clinical trials: sponsored by Montefiore Medical Center
Acute Severe Pain
Titration of Intravenous Hydromorphone
This is an exploratory, hypothesis-generating safety and efficacy study for patients who come to the ER in acute (less than 7 days in duration) severe pain. Patients with chronic pain will not be enrolled.
- Trial name
- NCT01892709
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Asthma, Children
Addressing Barriers to Physical Activity in Inner-City Schoolchildren With Asthma
This proposal will address the existent gaps in the literature by identifying barriers and facilitators to participation in physical activity in inner-city minority elementary schoolchildren with asthma, more that half of whom…
- Conditions
- Asthma, Children, Physical Activity
- Trial name
- NCT01873755
- Testing
- asthma physical activity intervention
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Montefiore Medical Center
HIV/AIDS
HIV Jail POC-AgAB Testings
"Enhancing a universal testing and treatment strategy in jail to promote viral load suppression among justice-involved people living with HIV" is an observational research study led by Dr.
- Trial name
- NCT04296331
- Testing
- POC, Ag/Ab, POC + Ag/Ab
- Where
- United States
- Volunteers
- 6,613 people
- Sponsor
- Montefiore Medical Center
Pain, Postoperative
Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients
Methadone has several advantages over standard narcotic medications, especially when considering use after a typically painful surgery such as lumbar fusion.
- Trial name
- MAPS (NCT02989597)
- Testing
- Methadone Hydrochloride, Standard pain regimen, Spinal Fusion Surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Accidental Falls, Harm Reduction
Reducing Hospital Falls by Empowering Nurses to Provide Ambulatory Aids
This project proposes to evaluate the potential for nurses to assess if a patient who uses an ambulatory aid at home is fit to use one in the hospital, and the effect that providing ambulatory aids to hospitalized patients will…
- Trial name
- NCT03675503
- Testing
- Fall Prevention Decision Support
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Montefiore Medical Center
Neuroendocrine Tumors
Diagnosis and Staging of Neuroendocrine Tumors (NETs) Utilizing 68Ga-DOTATOC PET/CT Scan
The primary goal of the analysis is to estimate the diagnostic accuracy of Gallium 68 (68Ga) -DOTATOC PET/CT for detecting neuroendocrine tumors (NETs) compared to conventional imaging techniques such as Magnetic Resonance…
- Trial name
- NCT03136328
- Testing
- 68Ga-DOTATOC
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Covid19, Mucormycosis
Mucormycosis in COVID-19
The purpose is to allow phsyician reporters to contribute to MUNCO registry. Mucormycosis in COVID-19 is a rapidly escalating medical emergency reported in high numbers in India during the ongoing coronavirus surge.
- Conditions
- Covid19, Mucormycosis, Aspergillosis, Candida Infection
- Trial name
- MUNCO (NCT04935463)
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Montefiore Medical Center
Stroke (CVA) or TIA
Multiple Organized Systems for Engaging Stroke (MOSES)
Despite decades of national declines in stroke incidence, racial/ethnic and socioeconomic disparities in stroke prevalence and care remain pervasive and the gap in these disparities is widening.
- Trial name
- MOSES (NCT05780060)
- Testing
- Standard of care, RPM and digital feedback, Standard of care and RPM only
- Sponsor
- Montefiore Medical Center
Hematoma Postoperative, Venous Thromboembolism
Use of Tranexamic Acid in Reduction Mammoplasty
Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM.
- Trial name
- TREX-ARM (NCT04947514)
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Prematurity, Neurodevelopmental Disorder
Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
Preterm infants are vulnerable to brain injury, nutritional deficiencies and poor early growth which places them at increased risk for developmental problems later in life.
- Conditions
- Prematurity, Neurodevelopmental Disorder, Carnitine Deficiency
- Trial name
- NCT01783041
- Testing
- L-carnitine, 5% Dextrose
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- Montefiore Medical Center
Pain
Exparel Interscalene vs Indwelling Catheter
The investigators are comparing an indwelling catheter with intermediate duration local anesthetic to a single shot peripheral nerve block with long acting a local anesthetic (Exparel).
- Trial name
- NCT03827213
- Testing
- Exparel, Indwelling Interscalene Catheter
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Hidradenitis Suppurativa
A National Registry For Patients With Hidradenitis Suppurativa
The goal of this study is to get a better understanding of the skin condition, Hidradenitis Suppurativa, and to find out how the disease affects quality of life.
- Trial name
- NCT03289585
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Montefiore Medical Center
Acute Pain
Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED
Intravenous opioids are the mainstay of acute, severe pain treatment in Emergency Departments (ED) across the country. Acetaminophen, given orally, has also been used for treatment of mild to moderate pain.
- Trial name
- NCT03521102
- Testing
- Acetaminophen 1000mg IV, Hydromorphone 0.5 mg IV
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Montefiore Medical Center
Asthma, Aspirin-induced
Diagnosis of Aspirin Hypersensitivity in Aspirin Exacerbated Respiratory Disease
To diagnose aspirin hypersensitivity in asthmatics by using and safe, low-dose aspirin oral challenge. Hypothesis 1: A low dose of oral ASA (20 or 40 mg) will induce significantly different concentrations of arachidonic acid…
- Trial name
- ASAS (NCT01320072)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Montefiore Medical Center
Hidradenitis Suppurativa, Quality of Life
Impact of Hidradenitis Suppurativa on Quality of Life Functions
The goal of this study is to get a better understanding of the impact of Hidradenitis Suppurativa (HS) on the quality of life of patients with this condition.
- Trial name
- NCT03288337
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Montefiore Medical Center
Time, Patient Preference
DryShield vs Cotton Roll Isolation During Sealants Placement: Efficiency and Patient Preference
The goals of this study are to determine if 1) placement times of pit and fissure sealants using the DryShield system differ from those when using the cotton roll isolation technique; and 2) there is a significant difference in…
- Trial name
- NCT02995369
- Testing
- DryShield, Cotton rolls
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Montefiore Medical Center
Forearm Fracture, Ultrasound
Trial of Ultrasound Guidance for Reduction of Pediatric Forearm Fractures
The primary objective of this study is to assess the utility of ultrasound guidance in the closed reduction of pediatric forearm fractures in the pediatric emergency department.
- Trial name
- NCT03097757
- Testing
- Ultrasound - guided fracture reduction, Standard of care fracture reduction
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Knee Osteoarthritis, Knee Pain
The Effect of AposTherapy on Knee Pain
AposTherapy is a home based exercise program utilizing footwear that causes exercise with normal activity that may significantly improve function in patients with knee osteoarthritis since patients with knee osteoarthritis have…
- Trial name
- AposKnee (NCT03171168)
- Testing
- AposTherapy, Traditional Physical Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Montefiore Medical Center
Oncologic Complications, Quality of Life
Nutrition and Pharmacological Algorithm for Oncology Patients Study
Loss of appetite is a common symptom of patients with cancer and can cause distress which impacts patients and caregivers. Patients diagnosed with head/neck, lung or pancreatic cancer will be recruited for this study to decrease…
- Conditions
- Oncologic Complications, Quality of Life, Nutrition Poor, Head and Neck Cancer
- Trial name
- NCT04155008
- Testing
- Dexamethasone, Dronabinol, Mirtazapine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Montefiore Medical Center
Clostridium Difficile
Bezlotoxumab as Secondary Prophylaxis for C. Difficile in High-risk Hospitalized Patients Exposed to Antibiotics.
This study will examine whether the human monoclonal antibody, bezlotoxumab administered AFTER acute Clostridioides difficile (C.diff) has resolved, but during a period of subsequent antibiotic therapy, will eliminate the high…
- Trial name
- NCT03937999
- Testing
- Bezlotoxumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Montefiore Medical Center