Clinical trials: sponsored by NYU Langone Health
Traumatic Brain Injury
Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.
This project will examine if computerized cognitive remediation will improve working memory and attention in 25 adults with a mild, moderate, or severe brain injury and compare their cognitive performance to the control group of…
- Trial name
- NCT04349852
- Testing
- BrainHQ Cognitive Training Modules, BrainHQ People Skills Modules
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Airway Disease, Barrett Esophagus
Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)
A majority of Fire Department of New York (FDNY) World Trade Center (WTC) exposed rescue and recovery workers developed gastroesophageal reflux disease (GERD), a risk factor for Barrett's Esophagus (BE) and subsequent esophageal…
- Conditions
- Airway Disease, Barrett Esophagus, Gastroesophageal Reflux Disease
- Trial name
- NCT05216133
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Lumbar Degenerative Disc Disease
Prospective Study of Thoracolumbar Spinal Fusion Graft
This study is a single-center, prospective randomized clinical study intended to compare and evaluate the efficacy of subjects who are treated with bone marrow aspirate concentrate (BMAC) and allograft to iliac crest bone grafts…
- Trial name
- BMAC (NCT02297256)
- Testing
- BMAC & Allograft, Iliac Crest Bone Graft
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Colorectal Cancer Screening
Pilot Testing of a Colorectal Cancer Education Program
The primary objective of this study is to assess the feasibility, acceptability, and preliminary efficacy of a culturally and linguistically targeted, colorectal cancer (CRC) education program to improve CRC screening completion.
- Trial name
- NCT07361614
- Testing
- Educational Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Attention-deficit/Hyperactivity Disorder
An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening
The goal of this study is to extend the efficacy evidence of sustained release methylphenidate compound (JornayPM) in adults with Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT06577779
- Testing
- Methylphenidate Hydrochloride Extended Release Capsule
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)
This is a randomized controlled trial (RCT) of 4 weeks of study supplement N-acetylcysteine (NAC) versus placebo in persons with significant obstructive sleep apnea (OSA) who are receiving positive airway pressure therapy (PAP)…
- Trial name
- NCT06311045
- Testing
- N-acetylcysteine (NAC), Positive Airway Pressure (PAP) Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Diet Habit
Harvest Share Clinical Outcomes
This pilot study aims to assess the feasibility and acceptability of collecting clinical outcomes amongst Building Access to Food through System and Solidarity (BASIS) participants (s22-00299).
- Trial name
- NCT07548619
- Testing
- Community Supported Agriculture (CSA)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
GVHD
High-Dose Post-Transplant Cyclophosphamide and Bortezomib (CyBor) for the Prevention of Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
This is a single arm open label phase II clinical trial. Adult patients with hematological malignancies undergoing allogeneic HSCT from matched-related or unrelated donor are eligible for the study if they meet the standard…
- Trial name
- NCT03945591
- Testing
- Bortezomib, Cyclophosphamide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- NYU Langone Health
Ischemia
mHealth-CArdiac REhabilitation for INOCA
This is a multi-site phase II, 2:1 pragmatic randomized trial of 250 participants within the NYU Langone Health (NYULH) and Emory University Medical Center system to evaluate mobile health cardiac rehabilitation (mHealth-CR) in…
- Trial name
- NCT06829160
- Testing
- Communication with exercise therapist, mHealth-CR, Wearable activity monitoring device
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- NYU Langone Health
Diabetes, Obesity
AIManage Using an AI-driven CDS and Chatbot
The objective of this project is to define and test the GenAI-powered Clinical Decision Support (CDS) tool, AIManage, providing a broad range of incretin mimetic medication management services to optimize dose titrations.
- Conditions
- Diabetes, Obesity, Medication Side Effects
- Trial name
- NCT07546357
- Testing
- AIManage
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Cannabis Use Disorder
RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative
The purpose of this sham-controlled pilot randomized controlled trial (RCT) is to evaluate the feasibility, safety, and preliminary efficacy of a one-month intervention consisting of 20 home-based active or sham RS-tDCS sessions…
- Trial name
- NCT07184983
- Testing
- Active Transcranial Direct Current Stimulation (tDCS), Mindfulness meditation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- NYU Langone Health
Myocardial Infarction
Heart Attack Research Program: Platelet Sub-Study (HARP)
This prospective observational cohort study, will investigate the platelet phenotype, platelet genetic composition, and role of platelets as effector cells in women and men with myocardial infarction (MINOCA or MI-CAD) and…
- Trial name
- HARP (NCT03022552)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cardiovascular Diseases
HARP Mindfulness Study
This study was designed using the Multiphase Optimization Strategy (MOST) framework to determine whether two supplemental components increase the efficacy of a mindfulness-based cognitive therapy program delivered via telephone…
- Trial name
- NCT05841784
- Testing
- MBCT-T, Booster Mindfulness Sessions, Website Support
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- NYU Langone Health
Tympanic Membrane Perforation
Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations
This study is a double blinded, placebo-controlled phase II study evaluating the efficacy of FGF-2 for the treatment of chronic non-healing tympanic membrane perforations (TMP).
- Trial name
- NCT04960384
- Testing
- FGF-2
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- NYU Langone Health
Familial Dysautonomia
Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia
The purpose of this placebo controlled interventional study is to collect preliminary data on administering dexmedetomidine in patients with Familial Dysautonomia (FD) during a rapid cessation of autonomic crisis.
- Trial name
- NCT06148311
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Post Traumatic Stress Disorder
Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder
This study will enroll patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for post-traumatic stress disorder (PTSD).
- Trial name
- NCT05391971
- Testing
- Bupivacaine, Saline
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- NYU Langone Health
Transradial Access
Comparison of Merit Prelude Ideal and Terumo Glidesheath Slender Radial Artery Sheaths
The aim of this study is to determine physician preference of sheath type based on a qualitative survey utilizing an EPIC-based randomization platform.
- Trial name
- NCT07218406
- Testing
- Terumo Glidesheath Slender sheath, Merit Prelude Ideal sheath
- Where
- United States
- Volunteers
- 554 people
- Sponsor
- NYU Langone Health
Cardiac Arrest
Packed Red Blood Cell Transfusion During Cardiac Arrest
The purpose of this pilot interventional study is to collect preliminary data on administering packed red blood cell (PRBC) during cardiac arrest (CA).
- Trial name
- NCT06462027
- Testing
- Packed Red Blood Cells (1 unit), Packed Red Blood Cells (2 units), Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Kidney Stone
Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment of Nephrolithiasis With FANS Access Sheaths
The purpose of this study is to compare two laser technologies that are routinely used during ureteroscopy for the treatment of kidney stones.
- Trial name
- NCT07516106
- Testing
- Moses Holmium:YAG laser, Thulium:YAG laser
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Cardiac Arrest, Return of Spontaneous Circulation
Post-CA Neuroprotection With Magnesium
The purpose of this pilot interventional study is to collect preliminary data on administering magnesium sulfate as a neuroprotective medication in patients who achieved Return of Spontaneous Circulation (ROSC) following Cardiac…
- Trial name
- NCT06455514
- Testing
- Magnesium Sulfate, Saline
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- NYU Langone Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.