Clinical trials: sponsored by NYU Langone Health
Cardiovascular Diseases
Cleaner Air for Better Cardiac Biomarkers
This pilot project is a randomized, double-blind, sham-controlled trial investigating whether in-home air pollution reductions using portable air cleaners (PACs) can decrease circulating concentrations of biomarkers of…
- Trial name
- NCT05379400
- Testing
- Portable air cleaner (PAC)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Opioid Overdose
Multi-Center Randomized Controlled Trial of Relay- NYC's Nonfatal Overdose Response Program
The New York City (NYC) Department of Health and Mental Hygiene (DOHMH) has implemented Relay, a novel program that engages and intervenes with individuals in the ED following an opioid OD and for the next 90 days, with the goal…
- Trial name
- NCT04317053
- Testing
- RELAY
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- NYU Langone Health
Metabolic Syndrome
P20 Extending Sleep to Reverse Metabolic Syndrome
This pilot study will test the acceptability and feasibility of a sleep extension intervention in community-dwelling, short-sleeping, racially/ethnically diverse middle-aged adults with MetS.
- Trial name
- NCT03596983
- Testing
- Sleep Intervention, Week 2 Intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
Aphasia
Aerobic Exercise and Aphasia Treatment
The purpose of the study is to determine if speech therapy can be enhanced by Aerobic Exercise (AE). Investigators will use a single subject design to determine if aphasia therapy result in greater gains when combined with…
- Trial name
- NCT02999360
- Testing
- Language therapy, Background Music, Aerobic Exercise
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Reproductive Health
Youth-friendly Sexual and Reproductive Healthcare Pilot in Mumbai, India
This study will systematically adapt, pilot test, and evaluate an integrated community/facility intervention to improve the uptake of adolescent-friendly services for married and unmarried adolescent girls and young women (AGYW…
- Trial name
- NCT04307849
- Testing
- Adolescent Health Club, Wait-list Control
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Age-Related Macular Degeneration, Diabetic Retinopathy
Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp Configurations
In this study, participants will be imaged using two Optical Coherence Tomography (OCT) devices: device N, a standard conventional OCT device with an invention (comfortable chin and forehead rest that can be adjusted to fit each…
- Conditions
- Age-Related Macular Degeneration, Diabetic Retinopathy, Central Serous Chorioretinopathy, Glaucoma
- Trial name
- NCT05686421
- Testing
- OCT Imaging Using Device N, OCT Imaging Using Device C
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Crohn Disease
Induction Optimization With Stelara for Crohn's Disease
This is a 16-week randomized controlled trial comparing a second IV weight-based induction dose at week 8 to standard 90mg subcutaneous dose at week 8, with a primary endpoint of clinical remission at week 16.
- Trial name
- NCT04629196
- Testing
- Ustekinumab
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- NYU Langone Health
Developmental Dysplasia of the Hip
Sound Conduction of Infant Hips
The objective of this study is to collect data that will be used to later design a method for the early diagnosis of diagnosis of developmental dysplasia of the hip (DDH).
- Trial name
- NCT05188235
- Testing
- Acoustical Resonance Device
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Type 2 Diabetes
CHOlesterol Lowering and Residual Risk in Type 2 Diabetes
The purpose of this study is to investigate why individuals with type 2 diabetes are at increased risk for heart disease and stroke.
- Trial name
- CHORD (NCT04369664)
- Testing
- Statin, PCSK9 inhibitor, Ezetimibe 10mg
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Dementia
Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients
Dementia is a common problem for older patients presenting to emergency departments and for the family caregivers who often lack support, understanding, and skills to manage the problems related to the need for emergency…
- Trial name
- POISED (NCT03325608)
- Testing
- POISED Care
- Where
- United States
- Volunteers
- 889 people
- Sponsor
- NYU Langone Health
Graft-versus-host Disease
Cyclophosphamide, Abatacept, and Tacrolimus for GvHD Prevention
This is a single arm, open label, optimal 2-stage Simon design phase Ib-II clinical trial. Adult patients with hematological malignancies undergoing allogeneic HSCT from first- or second-degree haploidentical donor are eligible…
- Trial name
- NCT04503616
- Testing
- Cyclophosphamide, Abatacept, and Tacrolimus for GvHD Prevention
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- NYU Langone Health
Sepsis
Sepsis Pre-Alert Monitoring Intervention: Study to Investigate Targeted Enhanced Monitoring for Sepsis
Sepsis is a leading cause of death worldwide, and contributes to approximately 750,000 hospitalizations per year, a third of which may die.
- Trial name
- NCT03473769
- Testing
- Vital Signs at 2 Hours, Confusion Assessment method for the ICU (CAM-ICU)
- Where
- United States
- Sponsor
- NYU Langone Health
Heart Failure, Heart Failure With Reduced Ejection Fraction
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF) is a pragmatic, cluster-randomized, three-arm intervention trial that will compare the effectiveness of two…
- Trial name
- BETTER CARE-HF (NCT05275920)
- Testing
- Best Practice Alert (BPA), In-Basket Message
- Where
- United States
- Volunteers
- 2,211 people
- Sponsor
- NYU Langone Health
Cervical Spine Disease, Psychological Impairment
The Confounding Burden of Psychological Impairments in Cervical Spine Surgery
This is a single-center prospective randomized investigation of patients undergoing surgical arthrodesis for single or multi-level cervical disease, resulting in cervical radiculopathy.
- Trial name
- NCT03183713
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Nocturia
Pathophysiologic Study to Understand and Possibly Treat Nocturia
This study will mainly look at how well compression stockings decrease body weight between morning and night and the number of nocturia events, by preventing blood from pooling in your legs.
- Trial name
- NCT05298384
- Testing
- Compression stockings
- Where
- United States
- Sponsor
- NYU Langone Health
Arthrofibrosis of Knee
Losartan Use to Mitigate Arthrofibrosis Following Total Joint Arthroplasty
The purpose of this study is to determine the effect of Losartan, an Angiotensin II Receptor Blocker (ARB), on the formation development of arthrofibrosis in patients who have had a primary total knee arthroplasty.
- Trial name
- NCT06333522
- Testing
- Losartan
- Where
- United States
- Sponsor
- NYU Langone Health
Prostate Cancer
Sleep, Exercise, Nutrition and Survivorship in Prostate Cancer
The primary objectives of this study are to examine sleep, exercise, and nutrition in prostate cancer.
- Trial name
- NCT05318131
- Testing
- Sleep and Lifestyle Advice Website, Surveys and Sleep Monitors
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Radiculopathy
CBD for Chronic Radicular Pain on Chronic Opioid Therapy (COT)
This double-blind, placebo-controlled, exploratory trial is designed to compare effects of oral CBD 600mg to placebo (PCB) in 20 outpatients with chronic spinal radiculopathies (without co-occurring Opioid Use Disorder)…
- Trial name
- NCT04760613
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Neutrophils.Hypersegmented | Bld-Ser-Plas, STEMI - ST Elevation Myocardial Infarction
CLEAR SYNERGY Neutrophil Substudy
CLEAR SYNERGY is an international multi center 2x2 randomized placebo controlled trial of colchicine and spironolactone in patients with STEMI.
- Trial name
- NCT03874338
- Testing
- Colchicine Pill
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- NYU Langone Health
Primary Progressive Aphasia
Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA)
The purpose of this study is to establish the feasibility of a program of remotely supervised transcranial direct current stimulation (RS-tDCS) paired with language skills practice for people living with the semantic or logopenic…
- Trial name
- NCT05615922
- Testing
- Transcranial Direct Current Stimulation (tDCS), Word-Naming Activity
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- NYU Langone Health
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