Clinical trials: sponsored by NYU Langone Health
Meningioma
Phase II Study of 177Lu-DOTATATE Radionuclide in Adults With Progressive or High-risk Meningioma
This single arm, open-label study will evaluate the efficacy of Lutathera (177Lu-DOTATATE) administered intravenously every 8 weeks for a total of 4 doses in patients with progressive WHO I-III or residual high-risk Ga-DOTATATE…
- Trial name
- NCT03971461
- Testing
- Lutathera
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Cigarette Smoking
E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness
In this open-label, randomized controlled trial study, participants who smoke combustible cigarettes (CC) and are diagnosed with Serious Mental Illness (SMI) will be randomized in two arms to receive harm-reduction counseling and…
- Trial name
- NCT05815199
- Testing
- E-cigarette (EC), Nicotine Replacement Therapy (NRT), Harm-Reduction Counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Seizures, Seizure Disorder
Modulating Movement Intention Via Cortical Stimulation
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies.
- Conditions
- Seizures, Seizure Disorder, Psychogenic Movement Disorder
- Trial name
- NCT03233399
- Testing
- rTMS of left or right angular gyrus (AG) or frontal cortex (FC), Anodal tDCS of left or right AG or FC
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Depression
Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)
This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate depression in a double-blinded…
- Trial name
- NCT06455527
- Testing
- Active Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Medication Administered in Error
Supporting Safe Use of Medications by Parents After Infant Discharge From the Neonatal Intensive Care Unit
This is a randomized controlled study of parents of children to be discharged from the neonatal intensive care unit at Bellevue and Elmhurst hospitals.
- Trial name
- NCT04278690
- Testing
- HELPix, HELPix+Tech
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Patients Scheduled for Endoscopic Retrograde Cholangiopancreatography (ERCP) Procedure
XRAIconnect Image Guidance Software for ERCP Procedures
The purpose of this research is to establish the usability, feasibility and utility of using XRAIconnect, a software medical device for operative image guidance for endoscopic retrograde cholangiopancreatography (ERCP)…
- Trial name
- NCT07841886
- Testing
- XRAIconnect
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Cardiac Resynchronization Therapy, Magnetic Resonance Imaging (MRI)
MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)
The goals of this project are to: 1) explore the potential use of magnetic resonance imaging (MRI) data for improved prediction of response to cardiac resynchronization (CRT), and 2) use the MRI-derived data together with a…
- Trial name
- NCT02728336
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
Abbreviated Breast MRI (AB-MRI) With Golden-angle Radial Compressed-sensing and Parallel Imaging (GRASP)
The purpose of this study is to use a magnetic resonance imaging (MRI) sequence called golden-angle radial compressed sensing and parallel imaging (GRASP) as a noninvasive and fast way to measure the wash-in contrast (dye) in the…
- Trial name
- NCT03927768
- Testing
- Predictive Model, Breast Imagers
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- NYU Langone Health
Metamorphopsia, Aniseikonia
Virtual Reality Aniseikonia and Metamorphopsia Testing
The purpose of this study is to assess whether the use of small, lightweight, portable virtual reality headset devices can provide a more accessible, reliable, contained, and convenient testing environment compared to previous…
- Trial name
- NCT07838181
- Testing
- Aegenta VR
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Pre Diabetes
BRInging the Diabetes Prevention Program to GEriatric Populations
Over 24 million Americans are over 65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the…
- Trial name
- BRIDGE (NCT05166785)
- Testing
- DPP Tailored for Older Adults and delivered via Telehealth, In-Person Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Maternal Health
RESTORE - Phase II
The study will apply the principles of Community Based Participatory Research to evaluate implementation strategies, designed to assist in the delivery of an evidence-based lifestyle counseling intervention for pregnant…
- Trial name
- NCT06349070
- Testing
- Low Touch - Text Messaging Implementation Strategy, High Touch - Community Health Worker (CHW) Implementation Strategy
- Where
- 2 sites in United States
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Systemic Lupus Erythematosus
HEALTH Home Urinalysis Testing
Study participants enrolled in the SAMPLE Biorepository (s14-00487) who have provided permission to be contacted for future research will be enrolled and randomized (1:1) two-arm controlled) to either 1) perform weekly home-based…
- Trial name
- NCT07823478
- Testing
- Home Urine Testing
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- NYU Langone Health
Anhedonia, Emotional Blunting
Psilocybin as a Novel Therapy for Residual Anhedonia
This study is for adults with major depressive disorder (depression) who are currently taking an SSRI or SNRI antidepressant but continue to experience anhedonia (reduced interest or pleasure) and emotional blunting.
- Trial name
- NCT07607938
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
Type 2 Diabetes
LINK-IT: Leveraging vIdeos and commuNity Health worKers to Improve Diabetes OuTcomes
The overall goal of this study is to examine the efficacy of the video-based Diabetes Self-Management Education and Support (DSMES) (hereafter VIDEO), or the video-based DSMES+community health worker (CHW) intervention (hereafter…
- Trial name
- LINK-IT (NCT06319716)
- Testing
- Video-Based Diabetes Self-Management Education and Support (DSMES), Community Health Worker (CHW) Support
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- NYU Langone Health
Child Development
School-Based Mental Health Effectiveness Study
This study involves efforts to advance the science of prevention in early childhood mental health in low-resource communities. Investigators will assess the effectiveness, practical implementation strategies, and underlying…
- Trial name
- NCT04383327
- Testing
- ParentCorps-Professional Development (PD), T-Wellness
- Where
- 2 sites in Uganda
- Volunteers
- 2,444 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Patient Education and Counseling
Communication Compass
The primary purpose of this study is to develop, implement, and validate algorithm-based feedback reports (Communication Compass) that provides personalized, near-real-time feedback on internal medicine residents' patient…
- Trial name
- NCT07220070
- Testing
- Algorithm-Based Feedback Reports, Standard Curriculum
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Prostate Cancer
Short Course ADT for High Risk Low/Intermediate Risk ARTERA Prostate Cancer
For this study, high risk prostate cancer patients with lower risk ARTERA scores will be treated with 6 months of Androgen Deprivation Therapy (ADT) in conjunction with dose escalated radiotherapy to the prostate and nodes.
- Trial name
- NCT07801664
- Testing
- Androgen Deprivation Therapy (ADT), Radiotherapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
Stuttering
Stuttering and Neuromodulation
The purpose of this study is to collect preliminary data on the efficacy of transcranial direct current stimulation (tDCS) combined with traditional behavioral techniques to reduce stuttering severity and negative impact in…
- Trial name
- NCT07222163
- Testing
- Soterix Medical 1x1 tDCS system, Speech therapy sessions
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Alcohol Use Disorder
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
This is a double-blind, randomized, placebo-controlled Phase 2 mechanistic clinical trial designed to evaluate the therapeutic neural mechanisms of psilocybin in patients with alcohol use disorder (AUD), and to determine whether…
- Trial name
- NCT06349083
- Testing
- Psilocybin, Supportive therapy sessions
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis
Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders
This study is a pilot, proof of concept study to determine the effects of administering an oral short-chain fatty acid (SCFA) supplement to Rheumatoid Arthritis (RA) patients with inadequate response to methotrexate (MTX).
- Trial name
- EASi-RAIR (NCT05718583)
- Testing
- Butyrate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health