Clinical trials: sponsored by NYU Langone Health
Osteoarthritis
Geniculate Artery Embolization for Treatment of Osteoarthritis
Single-arm, single-center, no sham or placebo, prospective pilot trial designed to evaluate the feasibility and safety of transcatheter arterial embolization in patients with mild to moderate radiographic knee OA.
- Trial name
- NCT04379700
- Testing
- Transcatheter arterial embolization, Embozene™ Microspheres
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- NYU Langone Health
Phthalate Exposure, Bisphenol Exposure
Phthalate and Bisphenol Exposure During Minipuberty
Phthalates and bisphenols have been detected in a range of infant care products. This pilot study will test whether intervening on these sources of exposure during the critical period of minipuberty affects infants' body burden…
- Trial name
- NCT05864209
- Testing
- Phthalate- and Bisphenol-free Baby Products, Cloth Diapers, Conventional Disposable Diapers
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Ischemic Heart Disease
Rehabilitation at Home Using Mobile Health In Older Adults After Hospitalization for Ischemic Heart Disease
RESILIENT is a phase II, multi-center, prospective, pragmatic randomized clinical trial with blinded assessment of the primary endpoint.
- Trial name
- RESILIENT (NCT03978130)
- Testing
- mHealth-CR
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- NYU Langone Health
Schizophrenia, Schizophrenia Schizoaffective
Focused Ultrasound Modulation of the Globus Pallidus Interna in Schizophrenia
This is a single-site, phase 2, sham-controlled random-order cross-over pilot trial of PLIFUS targeting the right GPi in individuals with schizophrenia.
- Trial name
- NCT05643196
- Testing
- PLIFUS, MRI
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Food Choices
Influence of Social Media Ads on Food Choice
This is a randomized trial to examine the influence of race-congruent food marketing on social media among Black and White adolescents.
- Trial name
- NCT05380505
- Testing
- Racially Congruent Ads, Racially Incongruent Ads
- Where
- United States
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Chronic Pain, Musculoskeletal Diseases or Conditions
PiPT in ADSM With MSD
The study objective is to establish feasibility of implementing a psychologically informed rehabilitation strategy while concurrently assessing its' effectiveness in Active duty service members (ADSM) with musculoskeletal…
- Trial name
- NCT05132400
- Testing
- Psychological-informed Physical Therapy (PiPT) Training
- Where
- United States
- Volunteers
- 427 people
- Sponsor
- NYU Langone Health
Osteo Arthritis Knee
Melatonin Use After Primary Total Joint Arthroplasty
The purpose of this study is to determine the effect of melatonin supplementation on patient sleep quality, length of stay, and opioid consumption following primary, unilateral, elective total hip or knee arthroplasty.
- Trial name
- NCT04795336
- Testing
- Melatonin 5 mg
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- NYU Langone Health
Advanced Non-small Cell Lung Cancer
Bronchoscopic Cryo-Immunotherapy of Lung Cancer
This is a safety and feasibility study of bronchoscopic cryo-immunotherapy (BCI) of peripheral lung tumors in advanced non-small cell lung cancer for the intention of inducing anti-tumor immune responses.
- Trial name
- NCT04049474
- Testing
- ERBOKRYO® CA - Cryosurgical Unit with Flexible ERBECRYO Probe, 1.9 mm outer diameter (ERBE Inc., Tubingen, Germany)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- NYU Langone Health
Dysphagia of Newborn
Cold Milk for Dysphagia in Preterm Infants
It is estimated that 30-70% of very low birth weight (VLBW) preterm infants will be diagnosed with swallowing dysfunction (dysphagia), which often leads to airway compromise in the form of laryngeal penetration and/or tracheal…
- Trial name
- NCT04421482
- Testing
- Standard room temperature (RTS) feeding of milk/formula, Cold temperature (CS, at 4-9°C) of milk/formula
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Stroke
Exoskeletal Support in Stroke
This interventional study will measure motor performance, including 3D movement analysis and muscle activity, in response to exoskeleton assistance. The cohort design will compare stroke patients to healthy controls.
- Trial name
- NCT05996198
- Testing
- Oculus Rift headset, Exoskeleton Device
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Endometriosis, Post Operative Pain
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain…
- Trial name
- NCT05229653
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Hypertension, Medication Adherence
Peers and Technology for Adherence, Access, Accountability, and Analytics
The overall objective of this project is to utilize the PRECEDE-PROCEED framework to conduct transdisciplinary, translational implementation research focused on improving medication adherence for hypertension control.
- Trial name
- PT4A (NCT05051124)
- Testing
- Peer Delivery of Medications, Health Information Technology (HIT) Platform
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- NYU Langone Health
Herpes Zoster Ophthalmicus
Zoster Eye Disease Study
This is a multi-center, randomized, double-masked, placebo-controlled clinical trial of suppressive valacyclovir for one year in immunocompetent study participants with an episode of dendriform epithelial keratitis, stromal…
- Trial name
- ZEDS (NCT03134196)
- Testing
- Masked Oral Valacyclovir
- Where
- 78 sites in United States, Canada
- Volunteers
- 527 people
- Sponsor
- NYU Langone Health
Type2 Diabetes
A Mobile Health Intervention to Reduce Diabetes Disparities in Chinese Americans
Chinese Americans are one of the fastest growing immigrant groups in the US, who suffer disproportionately high type 2 diabetes (T2D) burden and have poorly controlled T2D.
- Trial name
- NCT03557697
- Testing
- Standard of Care, SMS Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Type2 Diabetes
i-Matter: Investigating an mHealth Texting Tool for Embedding Patient-reported Data Into Diabetes Management
This study will integrate a technology-based patient-reported outcome (PRO) system [herein MJS DIABETES] that incorporates patients' perspective of their disease and functional status into the management of type 2 diabetes (T2D)…
- Trial name
- NCT03652389
- Testing
- MJS Diabetes
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- NYU Langone Health
Osteoarthritis, Osteo Arthritis Knee
Colchicine for the Treatment of Osteoarthritis of the Knee
This prospective, double-blinded, placebo-controlled, randomized trial will enroll 120 SKOA subjects at the NYU Center for Musculoskeletal Care.
- Trial name
- CLOAK (NCT03913442)
- Testing
- Colchicine 0.8 mg or 0.6 mg orally once daily
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Breast Cancer
Phase II Study of Pembrolizumab and Nab-paclitaxel in HER-2 Negative Metastatic Breast Cancer
This is a single-arm open-label multi-cohort Phase II study evaluating the safety/tolerability and clinical activity of the combination of nab-paclitaxel and the antibody against programmed cell death 1 (PD-1), pembrolizumab, in…
- Trial name
- NCT02752685
- Testing
- Pembrolizumab, Nab-Paclitaxel
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Keratoconus, Glaucoma
Optic Nerve Head Structural Response to IOP Elevation in Patients With Keratoconus
The mechanism by which vision loss in glaucoma occurs is still unknown, but it is clear that increased Intraocular Pressure (IOP) is a major risk factor.
- Trial name
- NCT03560609
- Testing
- Ophthalmodynamometer, Goldmann applanation tonometer, Pentacam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- NYU Langone Health
Cultural Competency, Personal Reflection
Impact of Visual Arts Immersion
The purpose of this study is to enhance engagement, coping and self-reflection by attuning nurses to creative and observational skills drawn from a visual arts pedagogical framework.
- Trial name
- NCT05877976
- Testing
- Visual Arts Immersion
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Advanced Cancer, End Stage Organ Failure
Emergency Medicine Palliative Care Access
This is a two-arm, multi-site randomized controlled trial of 1,350 older adults (50+ years) with either advanced cancer (defined as metastatic solid tumor) or poor prognosis end-stage organ failure (New York Heart Association…
- Trial name
- EMPallA (NCT03325985)
- Testing
- Nurse-led telephonic case management, Facilitated,outpatient specialty palliative care
- Where
- 18 sites in United States
- Volunteers
- 1,606 people
- Sponsor
- NYU Langone Health