Clinical trials: sponsored by NYU Langone Health
Heart Failure
HCV Positive Heart Donors
Study subjects active on the waiting list for a heart transplant at the NYU Langone Transplant Institute who are hepatitis C (HCV) negative will receive a heart transplant from a donor who tests positive for HCV.
- Trial name
- NCT03382847
- Testing
- Transplant with HCV positive donor, followed by surveillance and treatment of viremia
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Cervical Elastography
Application of Cervical Elastography in Obstetrics
The purpose of this study is to develop cervical elastography nomograms using Samsung's novel technology "E-cervix" and determine its ability to predict preterm birth.
- Trial name
- NCT03902587
- Testing
- Samsung's E-cervix technology
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- NYU Langone Health
Hypotension, Hypertension
Accuracy of Non-invasive Non-oscillometric Blood Pressure Wristband
The primary objective of the present investigation is to determine the accuracy of a non-invasive non-oscillometric blood pressure wristband device when compared to invasive intra-arterial blood pressure monitors.
- Trial name
- NCT03629535
- Testing
- Non-invasive non-oscillometric blood pressure wristband device, Invasive intra-arterial blood pressure monitors.
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Lung Diseases, Medication Compliance
Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program
The purpose of this study is to understand why patients in the World Trade Center program have continuing breathing problems. This study will improve investigators understanding of breathing problems among individuals with World…
- Trial name
- NCT02024204
- Testing
- Fluticasone propionate 230mcg for 3 Months, Current Treatment or no treatment, Salmeterol 21mcg for 3 Months
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Interstitial Cystitis Bladder Pain Syndromes
PTNS Versus Sham Efficacy in Treatment of BPS
This is a prospective, single center, double-blind, randomized, controlled trial comparing the efficacy of percutaneous tibial nerve stimulation to sham in the treatment of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC)…
- Trial name
- NCT02747420
- Testing
- NURO TM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Breast Cancer
Prospective Trial of Two Prone Breast Radiotherapy Techniques With Randomization to Concurrent Versus Weekly Boost
1. To test the hypothesis that when prone, patients treated with 3D-CRT breast radiotherapy and randomly assigned to either a weekly or a daily boost to the tumor bed develop acute toxicity that is not significantly worse than…
- Trial name
- NCT01591811
- Testing
- Arm 1 Daily Boost of Radiation Therapy, Arm 2 Weekly Boost of Radiation Therapy
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- NYU Langone Health
Mild Cognitive Impairment
Cognitive Detection of Preclinical AD: Validation Using Biomarkers
The current study aims to validate several novel cognitive tasks expected to be sensitive to brain impairment in specific anatomic regions affected in preclinical Alzheimer's disease(pAD).
- Trial name
- NCT02616679
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Schizophrenia, Schizophreniform Disorder
Biomarkers in First Episode Schizophrenia
This study will identify and evaluate relevant biomarkers and structural brain imaging for understanding potential biological illness related mechanisms in medication-naïve subjects with early psychosis before and after…
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Depressed Type
- Trial name
- NCT02033382
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
Image Guided Radiotherapy (IGRT) for Prone Partial Breast Irradiation
Partial breast irradiation (PBI) is becoming a new paradigm for breast cancer radiation.[1] No type I or II evidence is currently available to demonstrate equivalence to standard whole breast radiotherapy, and a prospective…
- Trial name
- PBI (NCT02272400)
- Testing
- IGRT for prone partial breast irradiation (PBI)
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- NYU Langone Health
Breast Cancer
Concurrent Adjuvant Carboplatin and Accelerated Radiotherapy for Triple Negative Breast Cancer
The purpose of this study is to determine the safety and effectiveness of a combination of chemotherapy and radiotherapy in breast cancer patients after breast surgery.
- Trial name
- NCT01289353
- Testing
- Carboplatin, 3D-RT or IMRT
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- NYU Langone Health
Emotional Stress
Promoting Success for Pre-K Teachers, Families and Children
The current study examines the impact of ParentCorps in high-poverty Early Education Centers in New York City (NYC). The study is conducted within the context of the NYC Department of Education (DOE) Pre-K Thrive initiative.
- Trial name
- NCT03524105
- Testing
- Program for Parents (Parenting Program), Thrive Professional Learning
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hip Arthroscopy
Multimodal Analgesia With Acetaminophen vs. Narcotics Alone After Hip Arthroscopy
The purpose of this proposed study is to evaluate the efficacy of a multimodal approach to analgesia for patient's pain after hip arthroscopy and to also assess if this new approach will result in a reduction in post-operative…
- Trial name
- NCT03510910
- Testing
- Acetaminophen, Percocet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Urinary Stone
Effect of a High Citrate Beverage on Urine Chemistry in Urinary Stone Disease
This study will investigate the effect of a patented high citrate beverage on urine chemistry in patients with urinary stone disease (USD).
- Trial name
- NCT04697706
- Testing
- Moonstone, Water
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Health Knowledge, Attitudes, Practice
Methods to Improve Preventative Care Uptake
The proposed study examines whether providing patients with information on the incentives for following the preventative care guidelines available through their insurance has an impact on the update of these preventative services.
- Trial name
- NCT03685981
- Testing
- Incentives mailer
- Where
- United States
- Volunteers
- 3,145 people
- Sponsor
- NYU Langone Health
Smoking, Smoking, Tobacco
Financial Incentives for Smoking Treatment
The investigators plan to compare the impact of two approaches for smoking cessation on smoking abstinence, use of evidenced-based therapy, and quality of life among a diverse population of patients at the Manhattan campus of the…
- Conditions
- Smoking, Smoking, Tobacco, Tobacco Use Disorder
- Trial name
- FIESTA (NCT02506829)
- Testing
- Smoking cessation counseling (Quitline), Smoking cessation pharmacotherapy (e.g, nicotine replacement therapy), Financial incentives
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- NYU Langone Health
Prostate Cancer
PET/MRI Study of Men With Highly Suspicious MRI Lesions That Showed no Clinically Significant Prostate Cancer Following MRI Fusion Targeted Biopsy
The principal aim of this study is to determine if PET/MRI imaging with 18-F fluciclovine (Axumin) identifies those men with false negative MRI fusion targeted biopsy (MRFTB) of PI-RADS 4 and 5 lesions.
- Trial name
- NCT03635866
- Testing
- Fluciclovine PET/MRI
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Parkinson Disease, Multiple System Atrophy
Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease
To determine whether retinal abnormalities, as measured by high definition optical coherence tomography (HD-OCT) and visual electrophysiology techniques can be used as a clinical biomarker to monitor disease progression overtime…
- Conditions
- Parkinson Disease, Multiple System Atrophy, REM Sleep Behavior Disorder, Pure Autonomic Failure
- Trial name
- NCT02640339
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Psoriasis, Psoriatic Arthritis
Patterns After Administration of MCFAs in Psoriasis and Psoriatic Arthritis
This is a proof-of-principle, placebo-controlled, open label study to assess the improvement in the Treg counts and PASI Scores with PEVCO given at 1000 mg four times daily in patients with PsO (subjects may or may not have PsA)…
- Trial name
- PAMPPA (NCT03409211)
- Testing
- PEVCO, Dietary Supplement Capsules without Coconut Oil
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
Study of Concurrent Paclitaxel and Radiation: Correlation of Tumor Profiles With Pathologic Response
The need to understand LABC is especially compelling in populations and countries with limited resources, where breast cancer incidence is relatively low, but mortality is comparably high.
- Trial name
- NCT02280252
- Testing
- Paclitaxel, Radiation therapy
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- NYU Langone Health
Cerebral Palsy, Prosthesis User
Use of Low Cost Prostheses to Improve Upper Extremity Function in Children With Cerebral Palsy
The purpose of the study is to assess the effectiveness of an upper extremity prosthesis in improving the upper extremity function of children with cerebral palsy who have limited use of their hands.
- Trial name
- NCT03122171
- Testing
- Occupational Therapy Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
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