Clinical trials: sponsored by NYU Langone Health
Neurofibromatosis Type 2, Vestibular Schwannomas
Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas
The primary objective is to estimate the proportions of vestibular schwannomas (VS) and meningiomas after 10 days of exposure to the study drug RAD001 at a dose of 10 mg daily, as determined by immunohistochemistry.
- Conditions
- Neurofibromatosis Type 2, Vestibular Schwannomas, Meningiomas
- Trial name
- NCT01880749
- Testing
- RAD001
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- NYU Langone Health
Preterm Birth
Non Invasive Biomarkers to Identify Subjects at Risk for Preterm Delivery
The goal of this study is to identify a non-invasive predictor or predictors that will increase the clinician's ability to identify patients with preterm labor (PTL) at risk for preterm delivery (PTD).
- Trial name
- PTMARKER (NCT00919412)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Non-small Cell Lung Cancer (NSCLC)
Study of Combined Ionizing Radiation and Ipilimumab in Metastatic Non-small Cell Lung Cancer (NSCLC)
The purpose of this study is to investigate how effective and how safe the combination of radiation therapy and an investigational medication targeting the immune system known as Ipilimumab in the treatment of metastatic…
- Trial name
- NCT02221739
- Testing
- Ipilimumab, Radiotherapy (IMRT or 3-D CRT)
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis
Pilot Study of Transcranial Direct Current Stimulation (tDCS)
This study will test the tolerability and preliminary efficacy of transcranial direct current stimulation (tDCS) combined with a cognitive training program, remotely-delivered using a telemedicine protocol in 60 adults with…
- Trial name
- NCT02746705
- Testing
- Transcranial Direct Current Stimulation (tDCS), Cognitive Training Program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Ovarian Cancer, Breast Cancer
Cancer Screening and Prevention Program for High Risk Women
The purpose of this study is to collect information from a large group of women who may have a greater chance to develop cancer because of their own personal history of cancer or because of their family history of cancer.
- Trial name
- NCT00849199
- Where
- 3 sites in United States
- Volunteers
- 1,452 people
- Sponsor
- NYU Langone Health
Achalasia
Anterior Orientation vs Posterior Orientation in Per Oral Endoscopic Myotomy POEM for the Treatment of Achalasia
The purpose of this study is to compare the safety and efficacy of the anterior versus posterior myotomy technique in Per Oral Endoscopic Myotomy (POEM) for the treatment of Achalasia.
- Trial name
- NCT03228758
- Testing
- Per Oral Endoscopic Myotomy
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- NYU Langone Health
Opioid Dependence
Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments
This study will compare the effects of brief strengths-based case management (SBCM) to the effects of screening, assessment and referral alone (SAR) in opioid-dependent patients.
- Trial name
- NCT02586896
- Testing
- Strengths-based Case Management (SBCM), Screening, Assessment, and Referral (SAR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- NYU Langone Health
Cervical Disc Disease
Driving After Cervical Spine Surgery
This is a single-center, prospective controlled simulation study designed comparing and evaluating the driving performance of subjects who have had cervical spine surgery and the use of a validated driving simulator.
- Trial name
- NCT02782923
- Testing
- STISIM driving simulator
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Familial Dysautonomia
Telemedicine Clinical Trial for Cognitive Behavioral Therapy in Familial Dysautonomia
This is a single-blind, placebo-controlled, telemedicine clinical trial to assess the efficacy of cognitive behavioral therapy (CBT) in adult patients 18 years and older with familial dysautonomia (FD) and anxiety and/or…
- Trial name
- NCT03911063
- Testing
- CBT sessions, Talking Sessions
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pulmonary Fibrosis
A Pilot Study of Aerosol Interferon-gamma for Treatment of Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive disease for which there is no effective treatment. Interferon-gamma is a medication that has been used for other lung diseases to decrease scarring and fibrosis.
- Trial name
- NCT00563212
- Testing
- aerosol interferon-gamma
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- NYU Langone Health
Smoking
Feasibility and Acceptability of a Text Messaging Intervention to Increase Smoking Cessation in Vietnam
The purpose of this study is to develop and then test the feasibility, acceptability, and preliminary effect of a bidirectional text message smoking cessation intervention among Vietnamese smokers in Hanoi, Vietnam.
- Trial name
- NCT03219541
- Testing
- Interventional Automated mobile phone text, Control Automated mobile phone text
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Surgery
Patient Satisfaction With Postoperative Communication Modality
Communication between a surgeon and a patient in the immediate postoperative period is thought to influence patient satisfaction.
- Trial name
- NCT04338425
- Testing
- Voice call, Video call
- Where
- United States
- Volunteers
- 295 people
- Sponsor
- NYU Langone Health
Colorectal Cancer, Neoplasm Metastasis
Cetuximab Plus Biweekly Capecitabine and Oxaliplatin in KRAS Wild Type Metastatic Colorectal Cancer
This is a Phase II, open label, non-randomized study in subjects with histologically confirmed diagnosis of advanced KRAS wild type adenocarcinoma of the colon or rectum, who have not received prior chemotherapy for metastatic…
- Trial name
- NCT00444678
- Testing
- Cetuximab, Oxaliplatin, Capecitabine
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Septal Myectomy
On-pump Intraoperative Echocardiography
This pilot study uses an ultrasound probe that is currently clinically used to assess pituitary anatomy, the Hitachi-Aloka high resolution pituitary transducer to measure left ventricular (LV) septal thickness during…
- Trial name
- OPIE (NCT03094325)
- Testing
- Pre Operative On-pump intraoperative echocardiography, Pre Operative Transesophageal echocardiography (TEE) imaging, Post Operative On-pump intraoperative echocardiography
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Pain, Fracture
Single Shot Versus OnQ Pump in Extremity Fractures
Peripheral nerve blocks have been well studied in the literature with generally good results for controlling post operative pain following orthopaedic surgery. Regional anesthesia has many benefits.
- Trial name
- NCT02280291
- Testing
- Ankle SSB, Ankle OnQ, DR SSB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Hematopoietic Malignancies
Study of Nonmyeloablative Peripheral Blood Stem Cell Transplant With High-dose Posttransplantation Cyclophosphamide in Hematopoietic Malignancies Including Those That Are Challenging to Engraft
This is an open label phase II single arm study of peripheral blood stem cell transplantation and posttransplantation cyclophosphamide, using HLA full match or haploidentical related donors, in hematological malignancies…
- Trial name
- NCT03187756
- Testing
- Cyclophosphamide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Opioid Use Disorder
TAU Opioid Use Outcomes Following Discharge From Detoxification and Short Term Residential Programs Affiliated With CTN-0051
This is an observational, "ancillary study" intended to describe opioid use among opioid use disorder patients following their discharge into the community from inpatient detoxification and/or short-term residential treatment…
- Trial name
- NCT02730403
- Testing
- Treatment As Usual
- Where
- 5 sites in United States
- Volunteers
- 211 people
- Sponsor
- NYU Langone Health
Schizophrenia, Schizoaffective Disorder
D-Cycloserine Augmentation of Cognitive Behavioral Therapy for Delusions
This study is a placebo-controlled 12 week trial of DCS augmentation of once-weekly CBT sessions in 60 schizophrenia subjects with antipsychotic-resistant delusions.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- NCT01981759
- Testing
- D-Cycloserine, Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- NYU Langone Health
Osteoarthritis, Knee
Efficacy of AposTherapy® in Knee OA
A prospective, interventional, randomized, double-arm clinical evaluation study to examine the efficacy of AposTherapy® versus a control group, in the short-term at 6 months and in the long-term at 12 months post-treatment, with…
- Trial name
- NCT03153956
- Testing
- Calibrated AposTherapy®
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- NYU Langone Health
MRSA
Retapamulin as a Decolonizing Agent for MRSA
The purpose of this study is to investigate the efficacy of retapamulin to reduce carriage of MRSA via a randomized, double-blind, placebo-controlled clinical study testing retapamulin among patients with confirmed…
- Trial name
- NCT03304873
- Testing
- Retapamulin
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- NYU Langone Health
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