Clinical trials: sponsored by NYU Langone Health
Prostate Cancer (Diagnosis), Transperineal Cryoablation
Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)
The purpose of this study is to evaluate the feasibility, safety, and potential protective benefit of Barrigel, a hyaluronic acid-based rectal spacer, in patients undergoing prostate cryoablation for localized or recurrent…
- Trial name
- NCT07567027
- Testing
- Barrigel Injectable Gel, Cryoablation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
VEXAS Syndome, Autoinflammatory Disease
Autoimmune and Autoinflammatory Genetics Study
This is an exploratory natural history protocol that will enroll patients with known genetic diseases, such as VEXAS syndrome, or as yet undiagnosed disorders of inflammation with the goal of improving our understanding of…
- Conditions
- VEXAS Syndome, Autoinflammatory Disease, Autoimmune Disease, Rheumatic Disease
- Trial name
- NCT06004349
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Epilepsy
Hippocampal Oscillations During Exploration
The objective of this study is to determine how visuomotor exploration relates to hippocampal activity along its long axis. The study will investigate the neurophysiological mechanisms in the hippocampus during (1) visual…
- Trial name
- NCT07224191
- Testing
- Visual Exploration, Ambulatory Exploration
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Communication Disabilities
Implementation of Communication Disability Collection and Accommodations in Primary Care Settings
This multi-methods-multi-site study aims to adapt and evaluate the effects of an implementation support package of strategies to assist primary care clinics in documenting patients' communication disability (CD) and accommodation…
- Trial name
- DECA (NCT07656584)
- Testing
- Implementation Support Package
- Where
- 5 sites in United States
- Volunteers
- 126,870 people
- Sponsor
- NYU Langone Health
Sensorineural Hearing Loss, Cochlear Implantation
Perceptual Adaptation Following Cochlear Implantation (Aim 3a)
The goal of this study is to study the adaptation process in newly implanted Single-Sided Deaf Cochlear Implant (SSD-CI) users. Subjects will use four frequency maps for the first month after CI activation.
- Conditions
- Sensorineural Hearing Loss, Cochlear Implantation, Perceptual Adaptation
- Trial name
- NCT07039435
- Testing
- Alternative Frequency Mapping
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Malignant Glioma
Fitness and Nutrition in Glioma
This is a pilot study assessing the effects of combining a modified Atkins diet with a physical fitness regimen in patients with malignant glioma.
- Trial name
- NCT06665373
- Testing
- Modified Atkins Diet, Fitness Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Cochlear Implant Users
Early Cochlear Implant Use
This observational study will examine newly activated cochlear implant users and determine whether their abilities to discern simple sounds change and relate to improved speech perception.
- Trial name
- NCT07114744
- Testing
- Take home tests
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Sexual Health Communication Skills Training Intervention for Patients With Prostate Cancer
This is a pilot randomized controlled trial of a sexual health communication skills training multimedia intervention (Starting the Conversation [STC] adapted for patients with prostate cancer [PCa]) to improve patients' ability…
- Trial name
- NCT07655557
- Testing
- Starting the Conversation (STC), Time and Attention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Hypertension
Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention
Using a focused implementation research framework, the EPIS (Exploration, Preparation, Implementation and Sustainment) model in a type-2 hybrid design, the study will be conducted in 3 phases: 1) A pre-implementation phase that…
- Trial name
- NCT05048147
- Testing
- Community Mobilization
- Where
- 4 sites in United States, Nigeria
- Volunteers
- 1,280 people
- Sponsor
- NYU Langone Health
Blood Pressure, Medication Adherence
Addressing Antihypertensive Medication Adherence Through EHR-enabled Teamlets in Primary Care
The study team will conduct a cluster randomized control trial in 10 NYU primary care practices to assess the effectiveness and implementation of the multicomponent intervention on medication adherence and blood pressure control…
- Trial name
- NCT05349422
- Testing
- Electronic Health Record (EHR) Enabled Teamlets
- Where
- United States
- Volunteers
- 1,842 people
- Sponsor
- NYU Langone Health
Lung Cancer
Female Asian Nonsmoker Screening Study
The study team propose to develop a database and biorepository of Asian female never smokers. This population is at increased risk for developing lung cancer but do not meet current lung cancer screening criteria.
- Trial name
- FANSS (NCT05164757)
- Where
- United States
- Volunteers
- 1,041 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis, Depression
Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)
This project is a double-blind, sham-controlled, parallel-arm, randomized controlled trial. We will recruit n=170 people living with MS, who are experiencing an episode of depression in the context of a major depressive episode…
- Trial name
- NCT06901687
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- NYU Langone Health
Depression, MDD
Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)
This pilot study evaluates the feasibility, safety, and preliminary efficacy of home-based 60Hz intermittent light therapy in adults with a major depressive episode (MDE).
- Conditions
- Depression, MDD, Major Depressive Disorder, Major Depressive Episode
- Trial name
- NCT07111390
- Testing
- 60Hz Intermittent Light Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Leptomeningeal Metastases
Phase 1 Study of WBRT or PCSI With REYOBIQ for Leptomeningeal Metastases
This Phase 1 study is designed to assess the safety, tolerability, and schedule feasibility of administering Rhenium-186 NanoLiposome (REYOBIQ) at different dosing intervals following whole brain radiotherapy (WBRT) or proton…
- Trial name
- NCT07674693
- Testing
- 186RNL
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health
Stroke
Optimal Dosing of High-Intensity Locomotor Training for Step Attainment and Locomotor Outcomes in Stroke Patients Undergoing Acute Inpatient Rehabilitation
The purpose of this study is to elucidate optimal dosing for High Intensity Gait Training (HIGT) to reduce locomotor disability for those undergoing inpatient rehabilitation (IR) in the subacute phase of stroke recovery.
- Trial name
- NCT06637839
- Testing
- Moderate-Intensity Locomotor Training Program, High-Intensity Locomotor Training Program, High-Step Count Locomotor Training Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Hearing Impairment
Clinical Evaluation of Frequency Allocation for Bimodal CI Users
This study will examine experienced, bimodal cochlear implant (CI) patients who receive an alternative frequency allocation table (FAT) to determine how it improves sound quality, device satisfaction, and speech perception…
- Trial name
- NCT06663917
- Testing
- Experimental frequency allocation table (FAT) - 438 Hz, Standard FAT - 188 Hz
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- NYU Langone Health
Health-Related Social Needs
Catch A Vibe - 24-00864
This study evaluates a proposed community-based implementation strategy to scale up screening, identification, and intervention on Health-Related Social Needs (HRSN) among persons on Long-Acting Injectable Pre-exposure…
- Trial name
- NCT07116629
- Where
- 2 sites in United States
- Volunteers
- 343 people
- Sponsor
- NYU Langone Health
Pregnancy
Prenatal Starting Early Program mHealth
The purpose of this interventional trial is to test the efficacy of the remote delivery of the StEP:Prenatal intervention compared to standard prenatal care in pregnant individuals planning to receive prenatal and pediatric care…
- Trial name
- NCT06087133
- Testing
- StEP:Prenatal, Routine Care
- Where
- United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Human Immunodeficiency Virus, Hypertension
Integration of Hypertension Management Into HIV Care in Nigeria
This study evaluates a tailored-practice facilitation (PF) strategy for integrating a task strengthening strategy for hypertension control (TASSH) for the care of patients living with HIV (PWH) within primary health centers…
- Trial name
- TASSH NIMR (NCT04704336)
- Testing
- Task-shifting strategy for HTN control (TASSH) protocol
- Where
- 2 sites in United States, Nigeria
- Volunteers
- 830 people
- Sponsor
- NYU Langone Health
HIV
HIV Antibody Increases Following Viral Rebound in People Receiving Antiretroviral Therapy
The purpose of this study is to establish a proof-of-concept for whether rapid test can detect viral rebounds that occurred within a retrospective time window among PLHIV receiving ART in the United States and sub-Saharan Africa.
- Trial name
- NCT07665060
- Where
- United States
- Volunteers
- 6,100 people
- Sponsor
- NYU Langone Health