Clinical trials: sponsored by NYU Langone Health
HIV
HIV Antibody Increases Following Viral Rebound in People Receiving Antiretroviral Therapy
The purpose of this study is to establish a proof-of-concept for whether rapid test can detect viral rebounds that occurred within a retrospective time window among PLHIV receiving ART in the United States and sub-Saharan Africa.
- Trial name
- NCT07665060
- Where
- United States
- Volunteers
- 6,100 people
- Sponsor
- NYU Langone Health
Opioid-use Disorder
Smartphones for Opiate Addiction Recovery
Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus…
- Trial name
- SOAR (NCT05033028)
- Testing
- Smartphone app
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- NYU Langone Health
Colonoscopy
Evaluating the Effectiveness of a Colonoscopy Surveillance Recommendations Algorithm in Clinical Practice
The primary objective is to determine if the use of the colonoscopy surveillance recommendations algorithm increases the accuracy of surveillance timing recommendations compared to traditional methods.
- Trial name
- NCT07658716
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Idiopathic Generalized Epilepsy
Human Epilepsy Project 3
By carrying a careful, large-scale and ambitious prospective study of a cohort of participants with generalized epilepsy, the study team hopes to clarify the likelihood of response and remission in this type of epilepsy, and try…
- Trial name
- HEP3 (NCT05374928)
- Where
- 18 sites in United States, Australia
- Volunteers
- 316 people
- Sponsor
- NYU Langone Health
Hearing Loss
A Computational Approach to Optimal Deactivation of Cochlear Implant Electrodes
The goal of the present study is to use computationally driven models of speech understanding in cochlear implant (CI) users to guide the search for which combination of active electrodes can yield the best speech understanding…
- Trial name
- NCT05219474
- Testing
- Cochlear implant Computer Model Implementation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Type 2 Diabetes
Personalized Dietary Management in Type 2 Diabetes
In a randomized trial of 255 participants with early-stage T2D, participants will be randomized to 1 of 3 groups: Standardized, Personalized, or a Usual Care Control (UCC).
- Trial name
- DiaTeleMed (NCT05046886)
- Testing
- Standardized, Usual Care Control (UCC), Personalized Guidance to Minimize Postprandial Glycemic Response (PPGR)
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- NYU Langone Health
Chronic Stroke
Paired Vagus Nerve Stimulation Mechanisms
In this mechanistic study, 40 individuals with chronic stroke will be implanted with a small vagus nerve stimulation (VNS) device.
- Trial name
- NCT06716112
- Testing
- Vagus Nerve Stimulation (VNS) Device, Upper Extremity Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Postoperative Pain
Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation
This study is a prospective randomized trial examining the effect of tranexamic acid (TXA) and aminocaproic acid (ε-Ahx) with local anesthetics and thrombin in all electively created surgical wound beds in hand surgery to provide…
- Trial name
- NCT07644923
- Testing
- Bupivacaine, Lidocaine, Thrombin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Calorie Consumption
Effects of Racial Congruence, "Likes", and Food Images in Social Media Ads on Adolescents' Caloric Intake - Study 3
This is a randomized trial to to test the degree to which visual attention to unhealthy foods, racially congruent people, and/or "likes" in social media ads explains the relationship between ad exposure and calorie intake.
- Trial name
- NCT06969651
- Testing
- Black-Food, White-Food, Black-Non Food
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hypertension
Bridging the Evidence-to-practice Gap
The proposed project will address this evidence-to-practice gap by evaluating the effect of practice facilitation (PF) of the intervention implementation fidelity (primary outcome) and clinical measures at 12 months (secondary…
- Trial name
- NCT03713515
- Testing
- ALTA
- Where
- United States
- Volunteers
- 652 people
- Sponsor
- NYU Langone Health
Patients With Synucleinopathies, Neurogenic Orthostatic Hypotension
Natural History Study of Synucleinopathies
Synucleinopathies are a group of rare diseases associated with worsening neurological deficits and the abnormal accumulation of the protein α-synuclein in the nervous system. Onset is usually in late adulthood at age 50 or older.
- Conditions
- Patients With Synucleinopathies, Neurogenic Orthostatic Hypotension, Pure Autonomic Failure, REM Sleep Behavior Disorder
- Trial name
- NCT01799915
- Where
- 8 sites in United States, Argentina and 2 more
- Volunteers
- 800 people
- Sponsor
- NYU Langone Health
Food Selection
Influence of "Likes" in Social Media Food Ads on Black and White Adolescents' Food Purchases - Study 2
This is a randomized trial to examine the influence of number of "likes"on social media food ads on Black and White adolescents' food purchases
- Trial name
- NCT06969638
- Testing
- Black Ads, White Ads, Many Likes
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Knee Arthritis
Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) can lessen pain, improve function, and improve patient satisfaction in cases of knee osteoarthritis.
- Trial name
- NCT05020028
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Food Insecurity
Improving Food Access in East Flatbush Through a Community Partner Coalition in New York City (NYC)
The objective of this research study is to implement and evaluate a food pantry pilot program to improve access to food and overall diet quality in East Flatbush.
- Trial name
- NCT07078253
- Testing
- Produce box program
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tobacco Smoking
E-cigarette Harm Reduction Among PLWHA in South Africa
The purpose of this pilot randomized controlled trial study aims to address the unmet need for feasible and efficacious strategies for reducing combustible cigarette (CC) use among people living with HIV/AIDS (PLWHA) in South…
- Trial name
- NCT06169813
- Testing
- Nicotine Replacement Therapy (NRT), E-Cigarette (EC), Counseling
- Where
- South Africa
- Volunteers
- 106 people
- Sponsor
- NYU Langone Health
Acute Coronary Syndromes
Study of Women With Acute Coronary Syndromes and Nonobstructive Coronary Artery Disease
Approximately 600,000 women are treated for acute coronary syndrome (ACS) annually in the US. ACS includes heart attack and a milder form called unstable angina.
- Trial name
- SWAN (NCT00798122)
- Testing
- Intravascular ultrasound, MRI
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Perspectives About Online Information
The purpose of this research study is to understand the perspectives of U.S. adults on online information about prostate cancer.
- Trial name
- NCT07631858
- Testing
- Post (video) about prostate cancer, Post (text post) about prostate cancer, Survey
- Where
- United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Achilles Injuries Tendon
Blood Flow Restriction Therapy in Achilles Injury
Blood flow restriction (BFR) therapy is a brief and partial restriction of venous outflow of an extremity during low load resistance exercises.
- Trial name
- NCT04104126
- Testing
- Standard of Care Physical Therapy, Blood flow restriction
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- NYU Langone Health
Chronic Postsurgical Pain
Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain
The study utilizes a 3-arm placebo-controlled RCT to study the effectiveness of ketamine in reducing chronic post-mastectomy pain.
- Trial name
- KALPAS (NCT05037123)
- Testing
- Continuous ketamine infusion, Ketamine + Saline
- Where
- 14 sites in United States
- Volunteers
- 765 people
- Sponsor
- NYU Langone Health
Major Depressive Disorder, MDD
tDCS: Sleep to Mood in Depression (S2M-D)
The purpose of this study is to determine whether changes in sleep consolidation occur during home-based transcranial direct current stimulation (tDCS) in adults with moderate depression and whether these changes are temporally…
- Conditions
- Major Depressive Disorder, MDD, Depression, Major Depressive Episode
- Trial name
- NCT07572526
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- NYU Langone Health
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