Clinical trials: sponsored by Northwell Health
First Episode Psychosis
Artificial Intelligence to Measure Adherence to Oral Medication
The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis.
- Trial name
- NCT04046497
- Testing
- Smartphone App, Usual Care
- Where
- 5 sites in United States
- Volunteers
- 139 people
- Sponsor
- Northwell Health
Healthy Controls Group - Age and Sex-matched
Vagustim™ Transcutaneous Auricular Vagus Nerve Stimulation Devices
Transcutaneous auricular vagus nerve stimulation (taVNS) has become a therapy of interest for treating chronic immune-medicated illnesses in adults and children.
- Trial name
- NCT07791290
- Testing
- Vagustim Individual Device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Acute Myeloid Leukemia in Remission
Pilot Study of Reduced Venetoclax Exposure
Pilot Study of Reduced Venetoclax Exposure
- Trial name
- NCT07163793
- Testing
- Azacitidine, Decitabine, Venetoclax
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Northwell Health
Acute Leukemia
Prevention of Hospital Acquired Deconditioning in Hospitalized Acute Leukemia Patients
This study aims to decrease the incidence of hospital acquired deconditioning (HAD) and to help standardize daily physical exercise monitoring in acute leukemia patients with anticipated prolonged duration of hospital stay.
- Trial name
- NCT07122479
- Testing
- Three-Pronged Approach to Reduce Hospital Acquired Deconditioning
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Northwell Health
Schizophrenia, Schizo Affective Disorder
iTBS to Enhance Social Cognition in People With Psychosis
The goal of this clinical trial is to examine if iTBS applied to the DMPFC improves social cognitive performance compared to sham stimulation in people diagnosed with schizophrenia, schizoaffective disorder, schizophreniform…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Schizophreniform Disorders, Psychosis Nos/Other
- Trial name
- iSCIP (NCT06118268)
- Testing
- iTBS (Active)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Patellofemoral Pain Syndrome
Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome
The purpose of study is to evaluate the efficacy of the electrical muscle stimulation (EMS) device in patients with patellofemoral pain known as anterior knee pain. Usual treatment for it is physical therapy (PT).
- Trial name
- NCT03184545
- Testing
- EMS, Physical therapy
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Northwell Health
Inflammation, C-reactive Protein
What is the Effect of Increased Consumption of Fruit Juice on Exercise Capacity and Inflammatory Biomarkers?
Dietary patterns and physical inactivity common in Western societies have been associated with chronic low-grade inflammation and an increased risk of non-communicable health conditions.
- Conditions
- Inflammation, C-reactive Protein, Exercise Capacity
- Trial name
- NCT07862049
- Testing
- Active Fruit Juice Intervention, Control Fruit Juice Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
Stroke, Hemiparesis
Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke
To determine whether treatment with transauricular vagus nerve stimulation (taVNS) during the training of an affected upper limb of a patient with chronic stroke on a robotic motor task alters the motor impairment.
- Trial name
- VaNSaRTS (NCT05339893)
- Testing
- In Motion Rehabilitation Robot
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Head and Neck Cancer, Alcohol Use, Unspecified
Alcohol Cessation Among Head and Neck Cancer Survivors
Head-and-neck cancers (HNC) account for 4 percent of cancer diagnoses in the United States and for more than 66,000 annual cancer diagnoses.
- Trial name
- NCT05570851
- Testing
- Alcohol Cessation Text Messages, Usual Care
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Northwell Health
Pain, Postoperative, Postoperative Pain, Acute
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries.
- Trial name
- NCT06379425
- Testing
- Acetaminophen, Celecoxib, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Meniscus Tear
Novel Bioactive Sleeve on Pain and PROMs
A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.
- Trial name
- NCT06041321
- Testing
- Reparel Sleeve
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Pulmonary Embolism
Treatment of Low-Risk Submassive Pulmonary Embolism With FlowTriever
This study is focused on investigating the efficacy and safety of the FlowTriever device to treat low-risk submassive pulmonary embolism.
- Trial name
- NCT05273762
- Testing
- FlowTriever
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Cranioplasty, Sonolucent Cranioplasty
Transcranial Ultrasound Via Sonolucent Cranioplasty
Transcranial Ultrasound via Sonolucent Cranioplasty is a prospective, single arm, observational, open label (non-blinded) study to collect real world evidence on the use of transcranial ultrasound via sonolucent cranioplasty.
- Conditions
- Cranioplasty, Sonolucent Cranioplasty, Reconstructive Cranioplasty
- Trial name
- NCT06097845
- Testing
- Transcranial Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwell Health
Benign Prostatic Hyperplasia
Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.
Many patients may face long-term urinary side effects following stereotactic body radiation therapy (SBRT), including increased urinary frequency, dysuria, and nocturia.
- Trial name
- NCT05148156
- Testing
- Urolift
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Essential Tremor
Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor After Successful Deep Brain Stimulation to the Dentato-rubro-thalamic Tract
The purpose of this study is to elucidate the structural connectivity of the dentato-rubro-thalamic tract (DRTt) and to detect functional network changes due to DRTt stimulation
- Trial name
- NCT04758624
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Northwell Health
Pancreatic Ductal Adenocarcinoma
Monthly Alternating NALIRIFOX and GnP in the First-Line Setting for Metastatic Pancreatic Ductal Adenocarcinoma
A prospective, interventional, single-center, single-arm, open-label, phase II study for patients with metastatic pancreatic cancer.
- Trial name
- NCT07163273
- Testing
- NALIRIFOX, Gemcitabine plus nab-Paclitaxel (GnP)
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- Northwell Health
Type 2 Diabetes
Continuous Glucose Monitoring and Behavioral Change Intervention for People With Type 2 Diabetes and Diabetes Distress
The purpose of this study is to use a Personalized Trial (N-of-1) design to test the effect of an intervention that pairs continuous glucose monitoring (CGM) with text message-delivered behavior change interventions for physical…
- Trial name
- NCT05941000
- Testing
- Self-Monitoring of Behavior for Physical Activity, Action Planning for Physical Activity, Self-Monitoring of Behavior for Mood
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Systemic Lupus Erythematosus
Transcutaneous Vagus Nerve Stimulation in SLE
Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease. Joint and muscle pain and fatigue are extremely common among patients and contribute to a reduced quality of life.
- Trial name
- TvSSLE (NCT06987565)
- Testing
- Active vagus nerve stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwell Health
Treatment Resistant Depression
DBS for Depression
The goal of this clinical trial is to demonstrate the feasibility and safety of deep brain stimulation in treatment resistant depression.
- Trial name
- NCT06096207
- Testing
- Medtronic SenSight Directional DBS lead
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwell Health
Cardiovascular Health Risk Communication, Cardiovascular (CV) Risk
Breast Artery Calcification (BAC) and Female Cardiovascular Disease
The investigators are recruiting women with and without Breast Artery Calcification (BAC) on their mammograms. Each participant in the study will undergo bloodwork at a Northwell Health lab, a cardiac CT scan, and fill out some…
- Conditions
- Cardiovascular Health Risk Communication, Cardiovascular (CV) Risk, Cardiovascular Disease Prevention
- Trial name
- NCT07809932
- Testing
- Cardiac CT Scan, Bloodwork
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwell Health