Clinical trials: sponsored by Northwell Health
Chronic Obstructive Pulmonary Disease
Consequences of Nocturnal and Daytime Hypoxemia in COPD
We will determine whether oxygen therapy lowers the level of substances in the blood which cause inflammation, which is one of the adverse effects of COPD and whether oxygen improves overall well being and quality of life as well…
- Trial name
- NCT00547456
- Testing
- Oxygen
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwell Health
Epilepsy, Psychiatric or Mood Diseases or Conditions
Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?
Women who take folate (folic acid) before getting pregnant can lower the risk of giving birth to infant with certain birth defects. However, some medications may affect the action of folate.
- Trial name
- NCT01231646
- Testing
- No intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwell Health
Chronic Lymphocytic Leukemia
Campath Maintenance in Chronic Lymphocytic Leukemia
This is a study designed to test whether giving campath (also known as alemtuzumab) on a maintenance schedule will prolong the time until the patient requires chemotherapy.
- Trial name
- NCT00587847
- Testing
- Campath
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Northwell Health
Interstitial Cystitis
Effect of Intravesical Lidocaine on Urodynamic and Symptomatic Parameters of Interstitial Cystitis
The purpose of this study is to determine the amount of improvement in bladder function and pain relief with the administration of 2% alkalinized lidocaine in patients with interstitial cystitis.
- Trial name
- NCT00823030
- Testing
- Urodynamic study, Lidocaine, Normal Saline
- Where
- United States
- Sponsor
- Northwell Health
Osteoporosis
The Relationship Between Osteoporosis and Chronic Oral Anticoagulation Therapy With Warfarin
The purpose of this study is to determine if osteoporosis is an unrecognized complication of chronic anticoagulation with warfarin.
- Trial name
- NCT00665613
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Asthma
Study of Pulmozyme to Treat Severe Asthma Episodes
Even with current standard ED treatments 20-25% of patients presenting to the ED with an acute asthma episode will still require hospitalization. For patients unresponsive to beta-agonists the admit rates will be higher.
- Trial name
- NCT00169962
- Testing
- rhDNAse (pulmozyme)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Northwell Health
Atrophy of Vagina, Vaginal Ulceration
Vaginal Creams to Reduce Vaginal Erosion in Pessary Users
To compare the use of Estrace ® vaginal cream against a placebo vaginal cream in reducing symptomatic vaginal discharge and vaginal erosion in patients who are using the Gellhorn or Ring with support pessaries.
- Conditions
- Atrophy of Vagina, Vaginal Ulceration, Vaginitis
- Trial name
- NCT02316249
- Testing
- Estradiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Cardiopulmonary Failure
Evaluation of Ultrasound of the Heart in Patients With Low Blood Pressure
Hypothesis: Goal-directed echocardiography by trained critical care physicians is equivalent to that of echocardiography technicians/cardiologists for the purpose of determining etiology (reason) of cardiopulmonary failure.
- Trial name
- NCT01723176
- Testing
- Echocardiography
- Where
- United States
- Sponsor
- Northwell Health
Hip Replacement, Hip Implant
Investigation of Systemic Metal Ion Concentration Following a Ceramic-on-metal Total Hip Arthroplasty
This is a pilot study to compare systemic concentrations of cobalt and chromium in patients that have previously undergone total hip arthroplasties with ceramic on metal and metal on metal bearing surfaces.
- Conditions
- Hip Replacement, Hip Implant, Total Hip Arthroplasty, Orthopaedic Surgery
- Trial name
- NCT00883805
- Testing
- Blood draw, X-Ray of Hip
- Where
- United States
- Sponsor
- Northwell Health
Parkinson's Disease
Parkinson's Disease Genetics Database
The goal of the study is to develop and organize an effort to identify genes that determine an individual's risk for developing Parkinson's disease (PD). 1.
- Trial name
- NCT00855556
- Testing
- blood draw
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwell Health
Focal Segmental Glomerulosclerosis
Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability Factor
This study is a proof-of-concept clinical study designed to test the hypothesis that oral administration of galactose can lower the level of a circulating factor that increases glomerular permeability to albumin in patients with…
- Trial name
- NCT00816478
- Testing
- Galactose
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Schizophrenia
Neurocognitive Effects of Ziprasidone: Relationship to Working Memory and Dopamine Blockade
Ziprasidone is a newer drug intended for the treatment of the symptoms of schizophrenia. This new drug may have an added benefit of being able to help with some of the difficulties in problem solving and memory that many patients…
- Trial name
- NCT00225498
- Testing
- ziprasidone vs risperidone or olanzapine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Northwell Health
Rheumatoid Arthritis
Genetic Registry for Rheumatoid Arthritis
Many genes are thought to contribute to rheumatoid arthritis (RA). This study will attempt to identify genes that may contribute to RA.
- Trial name
- NARAC (NCT00069472)
- Where
- United States
- Volunteers
- 1,062 people
- Sponsor
- Northwell Health
Immune System Diseases
Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways
The purpose of this study is to enrol generally healthy adults, who are asked to provide a blood sample, to study how the immune system works.
- Trial name
- GAP (NCT01161056)
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Focal Segmental Glomerulosclerosis
Effect of Galactose on Permeblity Factor in Patients With FSGS and CKD Stage 5
This study is a proof-of-concept clinical study designed to test the hypothesis that oral administration of galactose can lower the level of a circulating factor that increases glomerular permeability to albumin in patients with…
- Trial name
- NCT00816504
- Testing
- Galactose
- Where
- United States
- Sponsor
- Northwell Health
Neuroendocrine Tumors
Imaging of Neuroendocrine Tumors With PET and Fluoro-18-DOPA (F-DOPA)
Imaging of neuroendocrine (NETs), such as carcinoids and pheochromocytomas (PHEOs), is suboptimal, limiting curative treatment. The investigators wanted to explore the use of PET and F-DOPA i.v.
- Trial name
- NCT02539433
- Testing
- F-18-F-DOPA
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Northwell Health
Infection
Chlorhexidine Versus Betadine in Preventing Colonization of Femoral Nerve Catheters After Total Joint Arthroplasty (TJA)
Continuous femoral nerve block (CFNB) techniques continue to be increasingly used in the management of postoperative pain after total knee arthroplasty.
- Trial name
- NCT00896402
- Testing
- Skin antisepsis with chlorhexidine, povidone-iodine
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Healthy
Investigations Regarding B-cell Subsets in Humans
The aim of this research is to define the human equivalent of mouse B1 cells.
- Trial name
- NCT00926692
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Smoking Cessation
Comparison of Conservative and Aggressive Smoking Cessation Treatment Strategies in a Vascular Surgery Office Practice
The aim of this study is to prove that the use of Bupropion with counseling works better than counseling alone for patients to quit smoking.
- Trial name
- NCT01850589
- Testing
- Aggressive Therapy
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Depression, Bipolar Disorder
Liothyronine (T3) for Bipolar Depression
This study evaluates the efficacy of the thyroid hormone T3 for depression in patients with bipolar disorder. In this study patients will be randomized to receive T3 or placebo.
- Trial name
- T3 (NCT00790738)
- Testing
- Liothyronine (T3)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Northwell Health