Clinical trials: sponsored by Northwell Health
Alzheimer Disease
Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease
We are studying subjects with mild to moderate Alzheimer's disease who have been on a stable dose of any cholinesterase inhibitor [donepezil (Aricept), rivastigmine (Exelon), or galantamine (Razadyne)] for at least 3 months, and…
- Trial name
- NCT00551161
- Testing
- memantine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Northwell Health
Bipolar Disorder
Treatment and Outcome of Early Onset Bipolar Disorder
This study will compare the effectiveness in the maintenance of continuing adjunctive atypical antipsychotic medication compared to traditional mood stabilizer(s) alone in the maintenance treatment of adolescents with bipolar…
- Trial name
- NCT00048802
- Testing
- Lithium, Olanzapine, Divalproex
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
Bipolar I Disorder
Study of the Efficacy of Adjunctive Lithium Treatment for the Treatment of Psychotic Mania
The proposed pilot study is a placebo-controlled, parallel group, randomized clinical trial comparing two treatment strategies in adolescents with mania and prominent psychotic features.
- Trial name
- NCT01495156
- Testing
- Lithium treatment in combination with a SGA (Second Generation Antipsychotic)
- Where
- United States
- Sponsor
- Northwell Health
Postoperative Nausea and Vomiting
Aprepitant PO vs Ondansetron IV for Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) persists as one of the more common complications of surgery. Although rarely life-threatening, it is the postoperative outcome that is most unfavorable to patients, even more undesirable…
- Trial name
- NCT00699894
- Testing
- aprepitant 40 mg, ondansetron 4 mg
- Where
- United States
- Sponsor
- Northwell Health
Migraine, Headache
A Quality of Life Study in Patients With Migraines
The purpose of this study is to compare depressive characteristics in migraine patients to those observed in patients with epilepsy in a previous study, and determine whether those symptoms are unique to patients with epilepsy.
- Conditions
- Migraine, Headache, Depression
- Trial name
- NCT00298805
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Northwell Health
Vitamin B12 Deficiency, Type 2 Diabetes Mellitus
Metformin Use and Vitamin B12 Deficiency
The primary objective is to determine the incidence of Vitamin B12 deficiency in patients on metformin therapy for diabetes.
- Trial name
- NCT01136512
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pulmonary Hypertension
The Study Of CT Scans and Echo Parameters in Patients With PAH
Current standard of the diagnosis and monitoring of PHNT requiring combination of invasive and non-invasive tests. The goal of the study is to correlate data from CT scans, echocardiograms, right heart catheterization, PFTs…
- Trial name
- NCT00625963
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Northwell Health
Systemic Lupus Erythematosus
The Role of ITGAM in Systemic Lupus Erythematosus
Study to examine the role of ITGAM molecule in normal control subjects with known genetic variation in the ITGAM gene.
- Trial name
- NCT01230112
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Aspirin Resistance
Prevalence and Profile of Aspirin Resistance in Hemodialysis Patients
Dialysis patient could be more aspirin resistant than the general population based on data from chronic kidney disease patients
- Trial name
- NCT00792272
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Schizophrenia
Treating Drug-Resistant Childhood Schizophrenia
This study will compare clozapine and olanzapine (Zyprexa®) for the treatment of children and adolescents who have failed standard antipsychotic treatment for schizophrenia.
- Trial name
- NCT00048828
- Testing
- Olanzapine, Clozapine
- Where
- 3 sites in United States
- Volunteers
- 41 people
- Sponsor
- Northwell Health
Focal Segmental Glomerulosclerosis, Nephrotic Syndrome
Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental Glomerulosclerosis
The objective of this study is as follows: Perform genetic analysis to define the prevalence of each of the known gene mutations in an unselected cohort of patients with focal segmental glomerulosclerosis (FSGS) Perform a…
- Conditions
- Focal Segmental Glomerulosclerosis, Nephrotic Syndrome, Steroid Resistant Nephrotic Syndrome, Chronic Kidney Disease
- Trial name
- NCT00883636
- Testing
- Cardiovascular Assessment, Renal Assessment, Genetic Evaluation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Northwell Health
Thrombotic Microangiopathy, Hemolytic Uremic Syndrome
International Registry and Biorepository for TMA(Thrombotic Microangiopathy)
This registry will collect clinical data and store biosamples (seru, plasma, urine, and DNA) annually from pediatric patients with thrombotic mcroangiopathy
- Conditions
- Thrombotic Microangiopathy, Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura
- Trial name
- NCT00593229
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Healthy
Study to Evaluate Subclinical Atherosclerosis (an Early Sign of Heart Disease) in Healthy Adult Immigrant Asian Indians
Previous research has shown that Asian Indians are at relatively high risk for developing diabetes, heart problems and high blood pressure.
- Trial name
- NCT01104597
- Testing
- Flow Mediated Doppler (FMD), Nitroglycerin 0.4 mg sublingual
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Diabetes
Urine pH as a Predictor of Diabetes
Urine pH has been lately linked to insulin resistance. The early phase of Diabetes Mellitus involves insulin resistance. Thus, the investigators want to check if a simple cheap study like a urine analysis that can predict…
- Trial name
- NCT01017848
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Northwell Health
Hyperglycemia
Pre-admission Hyperglycemia and Its Effect on Morbidity and Mortality
It is currently standard of care in many Medical and Surgical ICU's to institute a nurse driven insulin protocol in maintaining tight glucose control in the critical patient. Many articles have been written to address this topic.
- Trial name
- NCT00871832
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northwell Health
Cardiovascular Disease
Prevalence of Clopidogrel (Plavix) Resistance in Hemodialysis Patients
The investigators are trying to find out if Clopidogrel (Plavix) is as effective in hemodialysis patients as in patients not hemodialysed.
- Trial name
- NCT01865890
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Obstructive Sleep Apnea, Diurnal Blood Pressure
Effect of Continuous Positive Airway Pressure (CPAP) Therapy on Changes of Blood Pressure Between Day and Night
to test whether using CPAP can restore the normal pattern of drop of blood pressure during sleep.
- Trial name
- NCT01865864
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Northwell Health
Hypertension
Post Kidney Transplant Nocturnal Hypertension Prevalence and Management Study
Hypertension (HTN) affects up to 75% of kidney transplant recipients and is associated with premature death. Nocturnal HTN is a common complication of ongoing essential HTN or a secondary cause of HTN.
- Trial name
- NCT01120613
- Testing
- Chronotherapy
- Where
- United States
- Sponsor
- Northwell Health
Diabetes
A Study of Improved Efficacy, Safety and Compliance to Administer Insulin in Pen vs. Vial and Syringe
This research is to determine the use of insulin pens compared to syringe and vial therapy in adults newly begun on insulin therapy during their hospital stay.
- Trial name
- NCT01857375
- Testing
- Insulin Pen Device
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Cardiovascular Outcome, Kalemia Control
Fiber Intake in an End Stage Renal Disease (ESRD) Population Followed Over 2 Years
Our research involves the detailed description of the content of the diet of x dialysis patients. For our purpose we used a newly developed "food frequency questionnaire".
- Conditions
- Cardiovascular Outcome, Kalemia Control, Lipid Profile
- Trial name
- NCT00874380
- Testing
- Increasing total fiber intake in patient's diet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwell Health