Clinical trials: sponsored by Odense University Hospital
Rectal Cancer, Ulcerative Colitis
Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study
Clinical experience show limited effect of the drug Loperamide used to decrease output in stoma patients. Therefore the investigators see the need for a randomized blinded clinical trial to determine the effect of Loperamide…
- Conditions
- Rectal Cancer, Ulcerative Colitis, Short Bowel Syndrome
- Trial name
- NCT02266849
- Testing
- Loperamide
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Prostate Cancer
Whole Body Bone Scan vs 18F-Choline PET/CT in Prostate Cancer
Prostate cancer is currently the leading newly diagnosed cancer in the industrialized world. Treatment of prostate cancer is highly dependent on the stage of the disease. Current methods for staging are known to be inaccurate.
- Trial name
- NCT02232685
- Testing
- 18F-Choline PET/CT
- Where
- Denmark
- Volunteers
- 143 people
- Sponsor
- Odense University Hospital
Ovarian Cancer
Dual PETOvac - Dual Time PET/CT in the Preoperative Assessment of Ovarian Cancer
The investigators want to compare the use of MRI with PET/CT preformed after 1 hour and 3 hours in preoperative assessment of resectability.
- Trial name
- Dual PETOvac (NCT01889615)
- Testing
- PET/CT(3hours]
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Odense University Hospital
Polycystic Ovary Syndrome, Overweight and Obesity
Motivational Interviewing as an Intervention for PCOS
The aim of the study is to examine if motivational interviewing can have a positive effect on weight loss over a 6 month period.
- Conditions
- Polycystic Ovary Syndrome, Overweight and Obesity, Motivation
- Trial name
- NCT02924025
- Testing
- Motivational interview
- Volunteers
- 28 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus
Retrograde Ejaculation and Sexual Dysfunction in Men With Diabetes Mellitus
Diabetic men and controls are examined for retrograde ejaculation, and erectile dysfunction is registered with a validated questionaire (International Index of Erectile Function-15).
- Trial name
- NCT01743599
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Odense University Hospital
Klinefelter Syndrome
Subcapsular Orchiectomy in Men With Klinefelter Syndrome
Men with Klinefelter syndrome undergo unilateral subcapsular ochiectomy, and the removed testicular tissue is examined for presence of sperm and cryopreserved in small pieces for fertility treatment and scientific purposes.
- Trial name
- NCT01750632
- Testing
- Orchiectomy
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Odense University Hospital
Atrial Fibrillation
Implantable Loop Recorder Versus Conventional Ambulatory Monitoring in Detecting Atrial Fibrillation After Pulmonary Vein Isolation
The primary aim of the study is to assess the efficacy of continuous rhythm monitoring with an implantable loop recorder (ILR) compared to conventional ambulatory electrocardiography in detecting episodes of atrial fibrillation…
- Trial name
- NCT00697359
- Testing
- Implantable loop recorder (ILR)
- Where
- 3 sites in Denmark, Russia and 1 more
- Volunteers
- 57 people
- Sponsor
- Odense University Hospital
Aortic Valve Stenosis, Heart Failure
Left Atrial Volume Index in Asymptomatic Aortic Stenosis
Aortic stenosis results in increased filling pressures of the heart. Size and function of the left atrium may be a marker for more advanced heart disease (heart failure) in patients with severe aortic stenosis, not presenting any…
- Trial name
- LAVIAS (NCT02395107)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Cardiovascular Disease, Coronary Artery Calcification
7 Year Follow-up Study of the DanRisk Population
OBJECTIVES: To investigate the incidence of cardiovascular events as well as progression of coronary artery calcium (CAC) in healthy middle-aged subjects over a period of 7 years, and the relation to traditional as well as new…
- Conditions
- Cardiovascular Disease, Coronary Artery Calcification, Atherosclerosis
- Trial name
- NCT02913144
- Volunteers
- 1,257 people
- Sponsor
- Odense University Hospital
Pulmonary Disease, Chronic Obstructive
Telemedical Training for Chronically Ill COPD Patients: a Cross Sectoral Study
Problem: Training is an important part of the treatment and rehabilitation of patients with chronic obstructive pulmonary disease (COPD) because training can increase the patient's muscle mass, lead to higher physical…
- Trial name
- NCT02754232
- Testing
- Telemedical training
- Sponsor
- Odense University Hospital
Postoperative Pain
The Effect of Phrenic Nerve Blockade on Acute and Chronic Shoulder Pain in Patients for Lobectomy and Pneumonectomy
The purpose of this study was to test whether peroperative infiltration of the phrenic nerve during lung surgery would protect patients against postoperative shoulder pain.
- Trial name
- TOPBLOC (NCT02173418)
- Testing
- Phrenic nerve block with Ropivacaine, Phrenic nerve block with saline
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- Odense University Hospital
Primary Spontaneous Pneumothorax, Pleural Disease
Study Designed to Optimize the Treatment of Primary Pneumothorax
Knowledge about incidence, risk factors and genetic predispositions of primary spontaneous pneumothorax in young adults is very limited, and treatment has also been controversial.The Aim of this study is to optimize the…
- Trial name
- TOPP (NCT02866305)
- Testing
- VATS bullectomy and mechanical pleuradesis., Chest tube insertion, Epidural
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Postoperative; Dysfunction Following Cardiac Surgery
Cerebral Energy State in Cardiac Surgery
Impaired cerebral function remains an important complication of cardiopulmonary bypass (CPB) during cardiac surgery. The aim of the present study is to investigate whether the lactate to pyruvate (LP) ratio obtained by…
- Trial name
- NCT02846818
- Testing
- Microdialysis
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Polycystic Ovary Syndrome
The Effect of Cipralex on Quality of Life, Adrenal Activity Glucose Metabolism, Physical and Mental Health in PCOS
Objectives: To investigate the effect of Cipralex versus placebo on stress hormones, glucose metabolism, physical and mental health and quality of life in polycystic ovary syndrome(PCOS). Treatment: 2x20 women for 12 weeks.
- Trial name
- NCT01961180
- Testing
- Cipralex
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Odense University Hospital
Pulmonary Embolism, Right Heart Strain
Study of Diagnosis and Pathophysiology of Pulmonary Embolism (APE 1 Trial)
The purpose of this study is to investigate which method and criterion for diagnosing pulmonary embolism is the best and determine the relationship between blood vessel constriction and clot size in patients developing heart…
- Trial name
- NCT00302601
- Testing
- Scintigraphic interpretation
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Odense University Hospital
Diabetic Foot Ulcer
Shockwave Therapy of Chronic Diabetic Foot Ulcers
Introduction: Foot ulcers are a feared complication among diabetic patients. The ulcers can cause pain, discomfort and reduced quality of life. The development of foot ulcers places the patients at a risk of amputation.
- Trial name
- NCT02251418
- Testing
- Extracorporeal shockwave therapy
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Odense University Hospital
Ulcerative Colitis, Pouchitis
Adalimumab in the Treatment of Chronic Pouchitis
This study wants to investigate the efficiency of biological treatment for chronic pouchitis. Chronic pouchitis is inflammation in a reconstruction after removal of the colon, a pouch.
- Trial name
- ADAP (NCT01670240)
- Testing
- Adalimumab
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Odense University Hospital
Ulcerative Colitis
Scintigraphic Evaluation of IPAA Function in Patients With Ulcerative Colitis
The aim of this study is to evaluate scintigraphic methods as objective factors for functional outcome in patients treated with ileal-pouch-anal anastomosis (IPAA).
- Trial name
- SKIPO (NCT02110862)
- Testing
- Transittime. Defecography
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Odense University Hospital
Colorectal Cancer
The Value of CE-LUS During Robot-assisted Surgery for Primary Colorectal Cancer
Laparoscopic ultrasound examination performed during surgery for primary cancer of the colon and rectum (CRC) has been shown to be able to detect liver metastasis that are not recognized by conventional computer tomography (CT…
- Trial name
- CE-LUS (NCT02457390)
- Testing
- CE-LUS
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Total Knee Replacement Surgery
Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
This study evaluates the effect of Iodine-impregnated self-adhesive plastic drapes (IIAD) on the quantity of skin bacteria, which is a known factor in the development of surgical site infections in orthopedic surgery.
- Trial name
- NCT02342561
- Testing
- Ioban 2 incision drape, 3M
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital