Clinical trials: sponsored by Odense University Hospital
Aortic Valve Stenosis, Left Ventricular Hypertrophy
Effect of Angiotensin II Receptor Blockers (ARB) on Left Ventricular Reverse Remodelling After Aortic Valve Replacement in Severe Valvular Aortic Stenosis
The consequence of aortic valve stenosis (AVS) is increased pressure load on the left ventricle which causes left ventricular (LV) hypertrophy, and myocardial stretch will cause activation of cardiac peptides and activation of…
- Conditions
- Aortic Valve Stenosis, Left Ventricular Hypertrophy, Atrial Fibrillation
- Trial name
- NCT00294775
- Testing
- Candesartan
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Lung Cancer
Positron Emission Tomography (PET)/Computed Tomography (CT) and Roentgen in Lung Cancer: Evaluation of Patients in General Practice
The prognosis of lung cancer depends much on the stage of the disease at the time of diagnosis. Only 16 % of lung cancer can be offered curative intended surgery.
- Trial name
- PROLOG (NCT00675168)
- Testing
- PET/CT (low-dose)
- Where
- 3 sites in Denmark
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Dermatitis, Contact, Dermatitis, Occupational
Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation
The purpose of this study is to compare the efficacy of glycerol ointment, triamcinolone acetonide ointment, clobetasol ointment and tacrolimus ointment on irritated skin in a cumulative skin irritation test model using healthy…
- Trial name
- WA+TR_1 (NCT00779792)
- Testing
- clobetasol, triamcinolone acetonide, tacrolimus
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type 2 Diabetes Mellitus
Genetic Variants and Phenotypic Characteristics of Patients With T2DM
Background: Genetic risk-markers associated with T2DM are thoroughly studied. So far, only a few genetic variants, also termed single nucleotide polymorphisms (SNP's), have been replicated in several studies and each of them…
- Trial name
- GenVarT2DM (NCT00760292)
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Polycystic Ovary Syndrome
Pioglitazone Treatment in Polycystic Ovary Syndrome
In this study, the investigators wish to investigate how pioglitazone treatment effects hirsute women. Hirsute women are often overweight and have an increased amount of male sex hormone in their blood.
- Trial name
- NCT00145340
- Testing
- pioglitazone
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Pain
Auditory Evoked Potentials and Experimental Pain
Monitoring of auditory evoked potentials (AEP) in patients during general anaesthesia is commonly used to ensure a sufficient hypnotic level during surgery.
- Trial name
- NCT00745472
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hirsutism
Bone Status and Insulin Resistance in Hirsutism
The purpose of this study is to investigate how the bones of hirsute women are different from bones of healthy women. The change in hormone content in the blood will also be investigated.
- Trial name
- NCT00143052
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Obesity, Type 2 Diabetes
Body Composition, Glucose Metabolism, Insulin Resistance and Gene Expression in Muscle Cells in Healthy Overweight Women
In this study, we will clarify the degree of insulin resistance and characterise muscle glucose metabolism and gene expression in a group of overweight healthy women.
- Conditions
- Obesity, Type 2 Diabetes, Polycystic Ovary Syndrome
- Trial name
- NCT00145392
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type 2 Diabetes Mellitus
South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus
The primary objective of this study is: To investigate whether insulin aspart with meals is better than a standard treatment with insulin NPH at bedtime, evaluated by HbA1c.
- Trial name
- SDDS (NCT00121966)
- Testing
- Insulin Aspart, Insulin NPH, Metformin
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Odense University Hospital
Type 2 Diabetes
Gene Expression Profiling and Bioinformatic Analysis Identifying Genes and Biochemical Pathways in Type 2 Diabetes
Type 2 diabetes is a disorder of the metabolic system that greatly affects individual health and imposes significant cost for society on health care.
- Trial name
- NCT00143013
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Esophageal Cancer, Gastric Cancer
Laparoscopic Ultrasound Guided Tissue Sampling in Patients With Cancer of the Upper Gastrointestinal Tract
Laparoscopic Ultrasound (LUS) is an important part of the pre-treatment evaluation of patients with upper gastrointestinal tract cancer (esophageal, gastric, pancreatic and liver cancer).
- Conditions
- Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Liver Cancer
- Trial name
- NCT00511264
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Odense University Hospital
Hyperhidrosis
Liposuction as Treatment for Excessive Axillary Sweat
The purpose of this study is to determine if suction-curettage of the axilla is favorable in regard to effect, recovery and cosmetic appearance compared to standard surgical excision of the skin of the axilla in case of excessive…
- Trial name
- NCT00228072
- Testing
- Suction-curettage
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Thyroid Diseases
Health-Related Quality of Life for Thyroid Patients
Background: Thyroid diseases are frequent. They include both metabolic changes and gland enlargement (goitre). Previous research and clinical suspicion indicate that the life quality of many patients is reduced despite successful…
- Trial name
- NCT00150033
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Odense University Hospital
Hip Fracture, Osteoporosis
Systematic Prevention of Further Fractures in Patients With Hip Fractures and Osteoporosis.
The purpose of this study is to determine if prevention of further fractures is possible through systematic evaluation for osteoporosis in patients with recent hip fracture
- Trial name
- NCT00414830
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Odense University Hospital
Postoperative Pain
OXY-1: The Pharmacogenetics of Oxycodone Analgesia in Postoperative Pain
Patients undergoing surgery (thyroidectomy and hysterectomy) will postoperatively receive oxycodone intravenously (IV) as pain management with morphine as an escape medicine, if there is insufficient pain relief with oxycodone.
- Trial name
- NCT00260260
- Testing
- Oxycodone
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Postoperative Pain
The Effect of Levetiracetam on the Postmastectomy Pain Syndrome
The aim of this study is determine whether or not the antiepileptic drug Levetiracetam is an effective treatment of the postmastectomy pain syndrome.
- Trial name
- NCT00262262
- Testing
- Levetiracetam (drug)
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Odense University Hospital
Myocardial Ischemia, Heart Failure, Congestive
Stem Cell Therapy in Chronic Ischemic Heart Failure
The purpose of this study is to determine whether intracoronary bone marrow transplantation can improve left ventricular ejection fraction in patients with severe ischemic heart failure and no other option for standard therapies…
- Trial name
- NCT00235417
- Testing
- Bone marrow transplantation
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
Pain, Polyneuropathies
Escitalopram as a Treatment for Pain in Polyneuropathy
Many people with polyneuropathy suffer from pain which is difficult to treat. Escitalopram is a relatively new drug used in the treatment of depression.
- Trial name
- NCT00162968
- Testing
- escitalopram
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Osteoporosis
Study of Male Osteoporosis and Aging
The aim of this study is to identify potential risk factors for fragility fractures in men.
- Trial name
- NCT00463411
- Where
- Denmark
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type 2 Diabetes
Influence of Physical Training on Mitochondrial Function in Type 2 Diabetic Patients
Physical activity as treatment for patients with type 2 diabetes (T2D). Treatment of T2D is often done by medication, changing the diet and increased physical activity.
- Trial name
- NCT00365495
- Testing
- Physical training (aerobic training)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital