Clinical trials: sponsored by Oregon Health and Science University
Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Carnitine Palmitoyltransferase Deficiency 2
Oral Ketones and Exercise Among Patients With Long-chain Fatty Acid Oxidation Disorders
The purpose of the study is to determine if an oral ketone beverage is safe and well-tolerated during moderate intensity exercise in participants with long-chain fatty acid oxidation disorders and if it will raise blood ketones…
- Conditions
- Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Carnitine Palmitoyltransferase Deficiency 2, Very Long Chain Acyl Coa Dehydrogenase Deficiency, Trifunctional Protein Deficiency
- Trial name
- NCT05411835
- Testing
- Nutritional Ketone Supplement
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Oregon Health and Science University
Accidental Falls, Injuries
The Safety Integration Stakeholders (SAINTS) Program to Integrate Worker and Patient Safety in Oregon Rural Hospitals
The safety integration stakeholders (saints) program to integrate worker and patient safety in Oregon rural hospitals. The rationale is that the saints program will positively impact outcomes by identifying and training peer…
- Trial name
- SAINTS (NCT06302088)
- Testing
- SAINTS program
- Volunteers
- 240 people
- Sponsor
- Oregon Health and Science University
Corneal Opacity
Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy
Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea.
- Trial name
- NCT01243931
- Testing
- OCT-guided laser phototherapeutic keratectomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oregon Health and Science University
Retinal Vein Occlusions
OCT in Retinal Vein Occlusions
Retinal blood vessel disease encompasses a wide variety of vision-threatening conditions. Of these conditions, retinal vein occlusions are the most common.
- Trial name
- NCT01992575
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Oregon Health and Science University
Uveitis
Optical Coherence Tomography (OCT) in Uveitis
Optical Coherence Tomography (OCT) machines are non-contact instruments that can provide micrometer (one one-thousandths) scale imaging of biological tissue.
- Trial name
- NCT02026128
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Oregon Health and Science University
Neovascular (Wet) Age-related Macular Degeneration (AMD)
OCT Angiography in Wet AMD
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD) 2.
- Trial name
- NCT02253030
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Retinal Artery Occlusions, Polypoidal Choroidal Vasculopathy
OCT in Rare Chorioretinal Diseases
This study will evaluate the total blood flow in the retina and choroid (structures in the back of the eye) by Doppler optical coherence tomography (OCT) and OCT angiography. Angiography is mapping of the blood vessels.
- Conditions
- Retinal Artery Occlusions, Polypoidal Choroidal Vasculopathy, Retinal Arterial Macroaneurysm, Juxtafoveal Telangiecasia
- Trial name
- NCT02141308
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Oregon Health and Science University
Cataract
Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography
The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases.
- Trial name
- OCT IOL (NCT00532051)
- Testing
- OCT measurements
- Where
- United States
- Volunteers
- 690 people
- Sponsor
- Oregon Health and Science University
Corneal Opacities (Scar and Stromal Dystrophy)
Observational Study of Corneal Opacities in Adults
A prospective observational study on corneal opacities (scar and stromal dystrophy) in adults (n=150) will be conducted at OHSU. The Optovue anterior segment OCT will be used to perform 3-D corneal scans.
- Trial name
- NCT02109471
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Oregon Health and Science University
Retinal Vasculitis
Optical Coherence Tomography (OCT) in Retinal Vasculitis
Retinal vasculitis is a sight-threatening inflammation that involves the blood vessels of the retina, the tissue that lines the inside of the eye.
- Trial name
- NCT01998464
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Oregon Health and Science University
Autism Spectrum Disorder
Autism ALERT Expansion
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- NCT06246890
- Testing
- Autism ALERT
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Obesity, Contraception
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- UPA-Obesity (NCT02859337)
- Testing
- UPA-ECx1, UPA-ECx2
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Nervous System Diseases, Diagnostic Imaging
MR, Histologic And EM Imaging Of Intravenous Ferumoxytol In Central Nervous System (CNS) Inflammation
This exploratory study utilizes ferumoxytol, an iron oxide nanoparticle MR contrast agent for imaging various inflammatory processes in the head and neck region, spine, including the central nervous system.
- Trial name
- NCT00659776
- Testing
- Ferumoxytol
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Oregon Health and Science University
Very Long-chain Acyl-CoA Dehydrogenase Deficiency, Trifunctional Protein Deficiency
Fatty Acid Oxidation Defects and Insulin Sensitivity
The purpose of this study is to learn more about what causes insulin resistance. It has been suggested that proper breakdown of fat into energy (oxidation) in the body is important to allow insulin to keep blood sugar in the…
- Conditions
- Very Long-chain Acyl-CoA Dehydrogenase Deficiency, Trifunctional Protein Deficiency, Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Medium-chain Acyl-CoA Dehydrogenase Deficiency
- Trial name
- NCT02517307
- Testing
- Intralipid/Heparin, Glycerol/Saline, Hyperinsulinemic euglycemic clamp
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Dementia, Alzheimer Disease
Assessing Acceptability, Cost, and Efficacy of STELLA-Support Via Technology
STELLA (Support via Technology Living and Learning with Advancing Alzheimer's disease and related dementias) is a multicomponent video-conference based intervention that aims to help family members caring for persons of dementia…
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout, Family Members
- Trial name
- STELLA (NCT04335110)
- Testing
- STELLA (Support via TEchnology: Living and Learning with Advancing Alzheimer's disease and related dementias)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Oregon Health and Science University
Physical Activity
Rural Libraries Promoting Walking and Walkability in Their Rural Communities
The investigators will randomize 20 rural libraries to implement either a group-based walking (standard approach) or a group-based walking combined with a civic engagement program (combined approach).
- Trial name
- NCT05677906
- Testing
- Walking only (Step It Up!), Combined (Step It Up! plus Civic Engagement)
- Where
- United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Drug Use, Peer Influence
The Peer-Based Retention of People Who Use Drugs in Rural Research
The purpose of this study is to, through several aims, test the effectiveness of peer-driven intervention and inform methods to optimize engagement in research in people who use drugs (PWUD) in rural America.
- Trial name
- PROUD-R2 (NCT03885024)
- Testing
- Retention Video
- Where
- 3 sites in United States
- Volunteers
- 850 people
- Sponsor
- Oregon Health and Science University
Parkinson Disease, Huntington Disease
Measuring Cortisol Levels in Persons With Parkinson's (PD)
The objective of this study is to evaluate the cortisol awakening response with persons with Parkinsons Disease (PD), Huntingtons Disease (HD), and controls.
- Trial name
- CORT-PD (NCT02727270)
- Testing
- No Intervention - Observational Study
- Where
- 2 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Trauma Injury
Prehospital Kcentra for Hemorrhagic Shock
This is a pilot trial being performed to evaluate the feasibility, to include the ability of EMS to identify patients in shock and the ability to package, store, and administer Kcentra in the field.
- Trial name
- NCT04019015
- Testing
- Prothrombin Complex Concentrate, Human
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Oregon Health and Science University
Alzheimer Disease, Early Onset
Digital Evaluations and Technologies Enabling Clinical Translation for AD
The DETECT-AD study (stands for "Digital Evaluations and Technologies Enabling Clinical Translation for Alzheimer's Disease") is a new study designed to improve clinical trials for early Alzheimer's disease.
- Trial name
- DETECT-AD (NCT05385913)
- Testing
- Multivitamin-no intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University