Clinical trials: sponsored by Oregon Health and Science University
Burnout
The Work-life Check-ins: a Supervisor-driven Intervention to Reduce Burnout in Primary Care
The objective of this study is to evaluate the effectiveness and process of frequent supervisor-employee check-ins in reducing burnout among employees of primary care clinics in Portland, OR.
- Trial name
- NCT05436548
- Testing
- Supervisor-employee frequent check-ins to identify and address work stressors, Usual practice waitlist controls
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cognitive Change
Sharing History Through Active Reminiscence and Photo-imagery (SHARP) Pilot Program
SHARP is a neighborhood-based and technology-supported approach to brain health for older Black adults that integrates walking and image-prompted social reminiscence to maintain or improve brain health.
- Trial name
- SHARP (NCT05906654)
- Testing
- Sharing History through Active Reminiscence and Photo-imagery (SHARP)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cognitive Change
Sharing History Through Active Reminiscence and Photo-imagery - With MCI
The SHARP-MCI study tests impact of walking and social reminiscence on cognitive function, blood pressure, and weight among healthy Black Americans and those experiencing mild cognitive impairment (MCI).
- Trial name
- SHARP-MCI (NCT05906667)
- Testing
- Sharing History through Active Reminiscence and Photo-imagery (SHARP)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - LNG
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- EC-Obesity (NCT02863445)
- Testing
- Levonorgestrel-based emergency contraception 1.5 mg, Levonorgestrel-based emergency contraception 3.0mg
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Dyspareunia
Treating Postmenopausal Dyspareunia Where it Hurts
The purpose of this study is to compare the effectiveness of two low doses of estrogen cream applied to a new location for the treatment of moderate or severe pain during sexual intercourse in postmenopausal women.
- Trial name
- NCT03240081
- Testing
- 50mcg estradiol cream, 100mcg estradiol cream
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes
Two Way Crossover Closed Loop Study MPC vs FMPD
An artificial pancreas (AP) is a control system for automatic insulin delivery. Our group has implemented a fading memory proportional derivative controller (FMPD) for use within an AP control system which has been evaluated in…
- Trial name
- NCT04771403
- Testing
- FMPD AP algorithm, MPC AP system, Dexcom G6 Continuous Glucose Monitoring (CGM) System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Oregon Health and Science University
Hemophilia
Motor Proficiency of People With Bleeding Disorders Using the BOT-2 (TM)
The purpose of this study is to find out if gross motor skills of children and young adults with bleeding disorders are different from those without bleeding disorders.
- Trial name
- NCT02279199
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Acute Lymphoblastic Leukemia, Childhood Lymphoblastic Lymphoma
Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma Gait Parameters Study
This purpose of this study it to characterize the walking patterns of children diagnosed with Acute Lymphoblastic Leukemia (ALL)and Lymphoblastic Lymphoma (LL) at different times in the treatment protocol and after completion of…
- Trial name
- NCT01565447
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hemophilia A, Bleeding Disorder
Characterizing the Impact and Treatment of Reproductive Tract Bleeding on Women and Post-menarchal Girls With Bleeding Disorders
Characterizing the impact and treatment of reproductive tract bleeding on women and post-menarchal girls with bleeding disorders.
- Trial name
- NCT03834727
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Oregon Health and Science University
Type 2 Diabetes, Hypertriglyceridemia
Effects of DPP-4 Inhibition on Triglycerides
The purpose of this study is to test the effects of saxagliptin, a treatment for diabetes, on fasting and post-meal blood triglyceride (blood fat) levels.
- Trial name
- NCT01527747
- Testing
- Saxagliptin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis, Fatigue
MitoQ for Fatigue in Multiple Sclerosis
The purpose of this study is to determine whether MS patients who receive Oral mitoquinone (MitoQ) have less fatigue than those receiving a placebo.
- Trial name
- MS (NCT03166800)
- Testing
- Mitoquinone
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Oregon Health and Science University
Weight Loss
Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity but results in loss of muscle mass. The investigators will test the hypothesis that consumption of an Essential Amino Acid-based nutritional formulation will maintain…
- Trial name
- NCT04751916
- Testing
- Essential Amino Acid Protein Supplement, Beneprotein®
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Cardiovascular Risk Factor
Vitamin C to Reduce Morning Cardiovascular Risk
This study will test the efficacy of Vitamin C to counteract morning cardiovascular (CV) risk markers in a randomized, double blind, placebo controlled crossover pilot study.
- Trial name
- NCT03290612
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
A Randomized Controlled Trial of a Multicomponent Walking Aid Program for People With MS
This is a randomized controlled trial of the Assistive Device Selection, Training, and Education Program (ADSTEP). ADSTEP is a training program of six weekly one-on-one sessions with a physical therapist intended to reduce falls…
- Trial name
- ADSTEP (NCT04145934)
- Testing
- ADSTEP
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Oregon Health and Science University
Health Behavior, Total Worker Health
Total Worker Health for Wildland Firefighters
The overarching goal is to develop, refine and disseminate a comprehensive, easily accessible and effective Total Worker Health (TWH) program for wildland firefighters (WFF).
- Conditions
- Health Behavior, Total Worker Health, Occupational Health
- Trial name
- NCT05753358
- Testing
- Total Worker Health for Wildland Firefighters
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mild Cognitive Impairment, Dementia Alzheimers
Protecting Alzheimer Caregivers Using Technology Through Staying Sharp
PROACTS is a Phase I/II study to assess the efficacy of AARP Staying Sharp online health program, focusing on the health of non-professional home-based caregivers of persons with Alzheimer's disease and related dementias (ADRD).
- Conditions
- Mild Cognitive Impairment, Dementia Alzheimers, Old Age; Dementia, Caregiver Burden
- Trial name
- PROACTS (NCT05260515)
- Testing
- Staying Sharp intervention
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Attention Deficit Hyperactivity Disorder
Micronutrients for Attention-Deficit Hyperactivity Disorder in Youth (MADDY) Study
This proposed research will use randomized control trial (RCT) methodology and compare micronutrients with placebo in 135 children with ADHD.
- Trial name
- MADDY (NCT03252522)
- Testing
- Broad Spectrum Micronutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- 3 sites in United States, Canada
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity, Insulin Resistance
Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on Ghrelin
The purpose of this study is to learn more about how insulin resistance (inability to process glucose correctly resulting in mildly elevated glucose levels) affects the hormone ghrelin.
- Trial name
- NCT00843791
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Head Trauma, Image, Body
Rapid MRI for Acute Pediatric Head Trauma
Pediatric head trauma is a leading cause of morbidity and mortality for children/adolescents. The current standard of care regarding imaging modality when concerned for an acute head injury is CT.
- Trial name
- NCT03291964
- Testing
- Rapid Brain MRI
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Oregon Health and Science University
Physiological Stress, Psychological Stress
Stress Reduction: A Pilot Study With Adolescents
This study will evaluate the feasibility of providing an onsite mindfulness intervention, delivered as part of the school health curriculum, to help high school-attending adolescents cope with stress.
- Trial name
- NCT02629016
- Testing
- Mindfulness, Wellness
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University