Clinical trials: sponsored by Oregon Health and Science University
Sleep Apnea, Gastroesophageal Reflux Disease
Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese Patients
This trial is enrolling patients who are already being seen at OHSU weight loss clinic or have been referred for clinical reasons by their physician to the OHSU weight loss clinic and are going to have a esophageal manometry that…
- Trial name
- NCT01099735
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
The primary aim of this study is to quantify and compare changes in lung volumes (as measured by functional residual capacity) in premature infants stable on continuous positive airway pressure (CPAP), and then randomized to two…
- Trial name
- NCT02249143
- Testing
- CPAP and room air
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Autism Spectrum Disorders, ADHD
Novel Measure of Social Deficits in Children
Autism Spectrum Disorders (ASD) feature impairments in social interaction and communication. Drug and behavioral treatments for ASD are undergoing rapid development, yet our diagnostic tools are not suitable for efficacy…
- Trial name
- OATS (NCT02035176)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Postoperative Vomiting and Nausea
Acupuncture and Nausea/Vomiting in Pediatric Patients
The purpose of this study is to investigate the effects of intraoperative P6 acupuncture plus standard therapy on postoperative nausea and vomiting in pediatric patients undergoing tonsillectomy with or without adenoidectomy.
- Trial name
- NCT01417741
- Testing
- Acupuncture Needle
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Oregon Health and Science University
Critically Ill
Determination of the Accuracy of a Non-Invasive Continuous Blood Pressure Device
This protocol will test a new non-invasive device, the T-line, in continuously determining heart rate and blood pressure in operative and critically ill patients.
- Trial name
- NCT01311128
- Testing
- T-line hemodynamic monitoring device (placement and use)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Health and Science University
Lactation
Dietary Lutein and the Retinopathy of Prematurity
The clinical trial aspect of this study is the provision of a lutein supplement to lactating women and compare the amount of lutein in the milk and blood with lactating women who do not receive the lutein supplement.
- Trial name
- NCT00672230
- Testing
- Lutein supplement
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes Mellitus, Hypoglycemia
Exercise Physiology Study
People with type 1 diabetes often find exercise very difficult to manage, because of the high risk for low blood glucose levels.
- Trial name
- NCT03090451
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Oregon Health and Science University
MAB, Pain
Opioid Analgesia for MAB
Our primary objective will be to determine if a strong opioid, oxycodone, given at a dose recommended for severe pain in addition to ibuprofen decreases maximum pain scores compared to ibuprofen and placebo in women undergoing…
- Trial name
- NCT03139240
- Testing
- Oxycodone 10mg oral
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Congenital Heart Disease, Heart Failure
Spironolactone in Adult Congenital Heart Disease
The purpose of this study is to see if the study drug called spironolactone reduces fibrous (stiffening) in heart muscle tissue and improves heart function.
- Conditions
- Congenital Heart Disease, Heart Failure, Endomyocardial Fibrosis
- Trial name
- NCT01069510
- Testing
- Spironolactone 25mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Depression
Circadian Effects of Escitalopram
The goal of the study is to obtain preliminary data that will test whether the antidepressant medication escitalopram resets the body clock: a collection of nerve cells in the brain that control the timing of many body processes.
- Trial name
- NCT01214044
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Oregon Health and Science University
Stress-related Problems
Effects of Stress-reducing Aromatherapy
The study purpose is to evaluate efficacy of stress-reducing aromatherapy and learn about how aromatherapy works.
- Trial name
- NCT01307748
- Testing
- aroma
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Clinical Outcomes of Deep Brain Stimulator (DBS) Electrodes Placed Using Intraoperative Computed Tomography (CT) and Frameless Stereotaxis
The purpose of this study is to determine whether performing deep brain stimulation surgery for Parkinson's disease using intraoperative imaging and frameless stereotaxis is noninferior to using frame-based stereotaxy and…
- Trial name
- NCT01703598
- Testing
- Deep Brain Stimulation, DBS surgery
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Oregon Health and Science University
Partial Epilepsy
Safety and Anticonvulsant Efficacy of Passiflora Incarnata Extract in Patients With Partial Epilepsy
The purpose of the Phase II clinical trial will be to see if a botanical extract from the plant Passiflora incarnata can improve seizure control and reduce anxiety in patients diagnosed with partial epilepsy.
- Trial name
- NCT00982787
- Testing
- Botanical extract from Passiflora incarnata
- Where
- United States
- Sponsor
- Oregon Health and Science University
Inattention, Impulsivity
Developmental Origins of Attention Deficit Hyperactivity Disorder
This is a study evaluating the relationship between prenatal nutrition and neural development in infants born to mothers with Attention Deficit Hyperactivity Disorder (ADHD).
- Conditions
- Inattention, Impulsivity, Anxiety
- Trial name
- NCT01982422
- Testing
- Whole Food, Nutrient-Dense Dietary Intervention, Standard of Care
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Alzheimer's Disease
Lutein and Alzheimer's Disease Study
Oxidative damage by free radicals may be involved in causing Alzheimer's disease (AD). Free radicals may lead to death of nerve cells and decline in brain function.
- Trial name
- LAD (NCT00596024)
- Testing
- lutein/zeaxanthin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Oregon Health and Science University
Obesity
Hypothalamic Functional Magnetic Resonance Imaging (fMRI) Response to Nutrients
The purpose of this study is to identify how certain parts of the brain that control appetite respond to changes in dietary carbohydrate and fat.
- Trial name
- NCT00686608
- Testing
- glucose, fructose, saline
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity, Prediabetic State
Physical Activity and Obesity
The purpose of the study is to see if a twelve-week exercise intervention in overweight or obese subjects with pre-diabetes or early disease course type 2 diabetes can lead to improved skeletal muscle capillary blood flow by…
- Conditions
- Obesity, Prediabetic State, Sedentary Lifestyle
- Trial name
- NCT02060240
- Testing
- High Activity
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Diabetes Mellitus
The Effect of Cinnamon Cassia on Diabetes Control and Cardiometabolic Risk Factors in Adults With Type 2 Diabetes Mellitus
The overall goal of this proposal is to establish the efficacy of cinnamon for the treatment of T2DM. Additional aims will assess the effect of cinnamon on cardiovascular risk factors and explore novel potential mechanisms of…
- Trial name
- NCT02942056
- Testing
- Cinnamon
- Sponsor
- Oregon Health and Science University
Contrast Induced Nephropathy
Safety Study Of N-Acetylcysteine For Prevention Of Contrast Induced Nephropathy In Patients w/Stage 3 Renal Failure
This will be a randomized prospective dose escalation clinical study of N-acetylcysteine (NAC) in patients with stage 3 or worse renal failure (Glomerular Filtration Rate 30-60 ml/min calculated with the Modification of Diet in…
- Trial name
- CIN-NAC (NCT00575419)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Oregon Health and Science University
Epilepsies, Partial
Pilot Trial of a Behavioral Treatment for Epilepsy
The purpose of this research study is to see if a behavioral program which includes a relaxation technique and lifestyle changes can improve seizure control and well-being in epilepsy patients.
- Trial name
- NCT00212745
- Testing
- Andrews/Reiter behavioral treatment for epilepsy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Oregon Health and Science University