Clinical trials: sponsored by Oregon Health and Science University
Depression, Dysthymia
Medications for the Treatment of Dysthymic Disorder and Double Depression
The purpose of the study is to evaluate the efficacy and safety of flexible doses of escitalopram (Lexapro) compared to sertraline (Zoloft) for treatment of Dysthymic Disorder.
- Trial name
- NCT00234312
- Testing
- escitalopram and sertraline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Pregnancy
The Physical Effects of Pain Catastrophizing in Labor
The purpose of this study is to determine whether labor self-efficacy (as determined by scores for the Lederman PSEQ II (self-efficacy scores) impacts the second stage 2 length (nromal vs.
- Trial name
- NCT01012466
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes
Exercise Detection Study
The risk of hypoglycemia in individuals with type 1 diabetes increases considerably during exercise. As a result, many patients with type 1 diabetes experience fear of and reluctance to pursue physical activity, in order to avoid…
- Trial name
- NCT02688218
- Testing
- Aerobic Exercise, Resistance Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Pain
Immunologic Response to Negative Cognition in Persons With Chronic Pain
Principal Investigator/Program Director (Last, First, Middle): Darnall, Beth APS Future Leaders in Pain Small Research Grants Application Page 5 Continuation Format Page Summary: Chronic pain is stressful, both physically and…
- Trial name
- NCT00677911
- Testing
- In-vivo pain catastrophizing induction
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Exercise, Brain Imaging, Cognition, and Gait in Parkinsonism
There is emerging research detailing the relationship between balance/gait/falls and cognition. Imaging studies also suggest a link between structural and functional changes in the frontal lobe (a region commonly associated with…
- Trial name
- EEforPD (NCT02231073)
- Testing
- Exercise and Education for Parkinson's Disease
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Glabellar Furrows
Botox Cosmetic and the Young Patient With Glabellar Furrows
The purpose of this study is to see if consistent treatment with Botox will lead to longer lasting effects. Botox is an injectable liquid that is approved by the U.S.
- Trial name
- NCT00856999
- Testing
- Botox
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Well-Being, Health Behavior
Study for the Employment Retention of Veterans
The Study for Employment Retention of Veterans (SERVe) is a randomized controlled trial, available exclusively to Oregon employers of veterans.
- Conditions
- Well-Being, Health Behavior, Workplace Outcomes
- Trial name
- SERVe (NCT03085953)
- Testing
- Veteran Supportive Supervisor Training, Waitlist Control
- Where
- United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Atopic Dermatitis, Eczema
The Effects of Emollient Therapy on the Skin Barrier
The goal of this study is to better understand what effect emollients (moisturizers) have on the skin in young children and adults.
- Trial name
- EES (NCT01291940)
- Testing
- Pediatric Moisturizer, Adult Moisturizer
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Eczema
Group Eczema Education Visits:Impact on Patient and Family Quality of Life
The objective of this study is to determine whether group educational visits improve the quality of life of patients referred to the Dermatology Clinic.
- Trial name
- NCT01143012
- Testing
- Group eczema education session, Control group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Oregon Health and Science University
Anterior Cruciate Ligament, Injury
Comparison of Doubled Quadrupled Versus Quadrupled Allograft Tissue Constructs for Anterior Cruciate Ligament (ACL) Reconstruction
The purpose of this study is to compare two different soft tissue allografts, double bundle tibialis anterior allograft or quadruple bundle hamstring allograft, used in repairing a torn anterior cruciate ligament (ACL) of the…
- Trial name
- NCT01148784
- Testing
- ACL reconstruction
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Oregon Health and Science University
Parkinson Disease, REM Sleep Behavior Disorder
Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease
This is a prospective observational study investigating the utility of 7 Tesla MRI to quantify nigrosome1 signal in a cohort of individuals with recent onset Parkinson's disease and in at-risk cohorts at a premotor state of…
- Trial name
- NCT03288909
- Testing
- MRI
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Morbid Obesity
Energy Expenditure and Gastric Bypass Surgery Study
The aim of this study is to assess whether the energy you burn daily increases after you have bariatric surgery. Until now, there hasn't been an effective way of measuring all activity on a daily basis.
- Trial name
- Energy (NCT00671957)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Obesity, Physical Inactivity
Changing Healthy Outcomes In Clinic Environments
This study will compare three methods of counseling to determine which is most effective at motivating participants to adopt healthy lifestyle habits.
- Conditions
- Obesity, Physical Inactivity, Diabetes
- Trial name
- CHOICE (NCT00674518)
- Testing
- One on one counseling, Group/team - based health education, PACE physician counseling
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Oregon Health and Science University
Pain
Hood to Coast Injury Study
The purpose of this study is to examine how certain kinds of fruit juice that contain natural antioxidants and natural anti-inflammatory properties may reduce exercise-induced muscle pain and injury.
- Trial name
- NCT00733395
- Testing
- Tart Cherry Juice, Fruit juice
- Volunteers
- 65 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Exercise & Brain Health in MS
The purpose of this study is to learn more about multiple sclerosis (MS). The investigators are studying whether aerobic exercise is better than a stretching program at improving brain health in people with MS.
- Trial name
- NCT02263339
- Testing
- Aerobic Exercise, Stretching, Aerobic Exercise- Healthy Subjects
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Respiratory Depression, Elective Surgery
Testing of the Apnea Prevention Device
This study is designed to test the ability of a computer-based algorithm to detect and intervene in cases of narcotic-induced respiratory depression.
- Trial name
- NCT00875134
- Testing
- Verbal prompt, Skin Stimulus
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Ovulation, Luteal Development
The Effect of a Non-hormonal Cox-2 Inhibitor (Celebrex) on Ovulation
The purpose of this study is to assess the effect that Celebrex (a COX-2 inhibitor and non-steroidal anti-inflammatory drug) has on ovulation.
- Trial name
- NCT01129245
- Testing
- Celebrex
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Spinal Cord Injury, Stroke
Proprioception Testing in Persons With Sensorimotor Impairment
In this study, an FDA-cleared device and type of treatment called "AMES," which stands for Assisted Movement with Enhanced Sensation, will be used to determine whether sensation in the upper limb of individuals with incomplete…
- Conditions
- Spinal Cord Injury, Stroke, Acquired Brain Injury
- Trial name
- NCT01974635
- Testing
- AMES Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Oregon Health and Science University
Extirpation of the Tooth Pulp
An in Vivo Comparison of the Debridement Efficiency of Needle Irrigation Versus Ultrasonic Irrigation
Study/Protocol Title: An in vivo comparison of the debridement efficacy of needle irrigation and ultrasonic root canal irrigation techniques 1.
- Trial name
- NCT00806273
- Testing
- Vista Ultrasonic Bleach Bypass System, Needle Irrigation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University