Clinical trials: sponsored by Oregon Health and Science University
Eales' Disease
Lucentis (Ranibizumab) for Eales' Disease
The primary objective of this protocol is to look at whether Lucentis (ranibizumab) is safe and effective when used for macular edema (retinal swelling) due to Eales' disease.
- Trial name
- NCT00384449
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Oregon Health and Science University
Feeding Intolerance
Preterm Neonatal Feeding Protocol Comparing Feed Administration Time
Doctors have tried many different methods of feeding to try to decrease feeding intolerance in preterm babies so that they spend less time receiving liquid nutrition and have fewer problems with feeding intolerance.
- Trial name
- NCT00997854
- Testing
- Length of time for feed administration
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cardiotoxicity
Vascular Cardiotoxicity of Ponatinib
Pre-clinical studies suggest that the third generation tyrosine kinase inhibitor ponatinib can result in microvascular angiopathy and acceleration of atherosclerosis.
- Trial name
- NCT03930394
- Testing
- Contrast ultrasound perfusion imaging
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Oregon Health and Science University
Hypertrophic Cardiomyopathy
Perfusion Imaging With Myocardial Contrast Echocardiography in HCM
The objective of this study is to determine whether myocardial contrast echocardiography in patients with cardiomyopathy (HCM) can detect resting hypo-perfusion due to fibrosis or stress induced perfusion defects due to…
- Trial name
- NCT02560467
- Testing
- Echo and myocardial contrast echocardiography perfusion imaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Respiratory Failure, Volume Overload
Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis
Patients who are on mechanical ventilation in an intensive care unit often require diursis as part of their pre-extubation regimen. The drug of choice for diuresis has traditionally been furosemide.
- Conditions
- Respiratory Failure, Volume Overload, Hypernatremia
- Trial name
- SHUM (NCT01617798)
- Testing
- Supplemental metolazone diuresis
- Where
- United States
- Sponsor
- Oregon Health and Science University
Peridialytic Hypotension
Predicting Hypotension During Dialysis in the ICU
Currently, decisions regarding volume management for dialysis sessions in the ICU are made in large part on the nephrologists'/intensivists' overall gestalt.
- Trial name
- NCT01171352
- Testing
- Transpulmonary Thermodilution
- Where
- United States
- Sponsor
- Oregon Health and Science University
Menorrhagia, Metrorrhagia
Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS)
This study evaluates the ability of tamoxifen to improve frequent or prolonged bleeding in new users of the 52mg levonorgestrel-releasing intrauterine device (IUD).
- Conditions
- Menorrhagia, Metrorrhagia, Medicated Intrauterine Devices
- Trial name
- NCT02824224
- Testing
- Tamoxifen
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
GI Colonization of Vancomycin-resistant Enterococcus
The Influence of Probiotics on Vancomycin-Resistant Enterococcus
Drinking probiotics in a the form of a yogurt drink will restore normal gastrointestinal (GI) bacteria in patients whose colon are colonized with vancomycin-resistant enterococcus (VRE).
- Trial name
- NCT00591474
- Testing
- probiotics, yogurt
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Oregon Health and Science University
Schizophrenia, Psychotic Disorders
A Multi-modal Approach to Addressing Cardiovascular Risk and Building Resilience in Youths With Psychosis
The purpose of this study is to determine the feasibility (≥ 50% completion rate) of a 6-week nutrition, movement, and mindfulness program for youth with recent diagnosis of psychosis.
- Trial name
- M3 (NCT02398292)
- Testing
- M3 Program, Control
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mevalonic Aciduria, Mevalonate Kinase Deficiency
Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency
Participants wanted for study of mevalonate kinase deficiency (MKD), mevalonic aciduria, or hyperimmunoglobulinemia with periodic fever syndrome (HIDS).
- Conditions
- Mevalonic Aciduria, Mevalonate Kinase Deficiency, Immune System Diseases, Periodic Fever Syndromes, Hereditary
- Trial name
- NCT00260299
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Oregon Health and Science University
Spinal Cord Injury, Paraplegia
Spinal Cord Injury Leg Rehabilitation
The purpose of this study is to determine if individuals with incomplete spinal cord injury (SCI) who remain unable to walk normally 1 year after their SCIs are able to sense and move the affected legs better after 10-13 weeks of…
- Conditions
- Spinal Cord Injury, Paraplegia, Quadriplegia, Tetraplegia
- Trial name
- AMES (NCT01498991)
- Testing
- AMES Treatment
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Oregon Health and Science University
Smith-Lemli-Opitz Syndrome
Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz Syndrome
The purpose of this study is to learn about Smith-Lemli-Opitz Syndrome (SLOS). SLOS is an inherited condition that is caused by the body not making an enzyme as it should. The body needs the enzyme to help make cholesterol.
- Trial name
- STAIR-SLOS (NCT01356420)
- Testing
- Cholesterol supplementation
- Where
- 5 sites in United States
- Volunteers
- 21 people
- Sponsor
- Oregon Health and Science University
Bronchopulmonary Dysplasia, Very Low Birth Weight
Preterm Infant Inhaled Albuterol Dosing
The purpose of this study is to help determine the best dose of inhaled albuterol sulfate in premature babies at risk of developing bronchopulmonary dysplasia (BPD).
- Trial name
- NCT02447250
- Testing
- Varied albuterol dose response
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Oregon Health and Science University
Cardiac Defect
Safety and Efficacy of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients
The investigators primary objective is to determine if acute normovolemic hemodilution (ANH) for pediatric cardiac surgical patients decreases the volume of blood products transfused during surgery and the immediate…
- Trial name
- NCT02751645
- Testing
- Acute Normovolemic hemodilution
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Crohn's Disease
Infliximab, Regulatory T Cells, IL2 and Crohn's Disease
Crohn's disease is an inflammatory (swelling and soreness) disorder of the digestive tract. Affected patients suffer from abdominal pains, diarrhea (sometimes bloody), weight loss.
- Trial name
- NCT01266785
- Testing
- Infliximab
- Where
- United States
- Sponsor
- Oregon Health and Science University
Competence, Self-efficacy
Quantifying the Influence of Expert Modeling
The purpose of this study is to learn more about the effects of various types of simulation preparation methods on novice nurses' competence and self-efficacy.
- Trial name
- NCT02100215
- Testing
- Common readings and educational handouts, Expert Modeling, Voice Over Power Point
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Spinal Cord Injury, Tetraplegia
Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury
The purpose of this study is to determine if tetraplegic individuals with incomplete spinal cord injury (SCI) who remain unable to move their arms normally 1 year after their SCIs are able to sense and move the affected arm(s)…
- Conditions
- Spinal Cord Injury, Tetraplegia, Paresis, Plegia
- Trial name
- NCT00833105
- Testing
- AMES treatment
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Contraception
Immediate Postplacental IUD Insertion
The study will be a randomized clinical trial. Women with less than 10 prenatal visits and/or 2 or more no show visits who desire an Intrauterine Device (IUD) will be considered for enrollment.
- Trial name
- NCT02169869
- Testing
- Mirena, Paragard
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Oregon Health and Science University
Surgical Wound Infections
Prevention of Neurosurgical Wound Infections
The goal of this study is to determine whether injecting the antibiotic vancomycin directly into surgical wounds can decrease the rate of infection following implantation of neurosurgical devices.
- Trial name
- POWI (NCT00915967)
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Rouxbe Pilot for MS
The purpose of this protocol is to collect data from approximately 15 multiple sclerosis (MS) patients who are participating in a pilot cooking course.
- Trial name
- NCT02424825
- Testing
- Cooking Course
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University