Clinical trials: sponsored by Oregon Health and Science University
Optic Neuritis
Lipoic Acid as a Treatment for Acute Optic Neuritis
The purpose of this study is to determine if oral lipoic acid can safely help relieve permanent optic nerve injury in patients diagnosed with acute optic neuritis.
- Trial name
- NCT01294176
- Testing
- Lipoic Acid
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Health and Science University
Contraception, Pain
The Effect of Nitroglycerin on the Intrauterine Device (IUD) Insertion Experience in Nulliparous Women
Increasing ease of access of long-acting birth control methods, like intrauterine devices (IUDs), is an important way to reduce the risk of unintended pregnancy.
- Trial name
- NCT01490073
- Testing
- Insertion of nitroglycerin ointment
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diabetes Mellitus, Type 2
Efficacy Study of Diabetes Group Visits
Much evidence exists that new, more effective methods of delivering care to diabetics are necessary. In our current system of delivering care, diabetes care is often done in the context of multiple other issues addressed during a…
- Trial name
- NCT01497301
- Testing
- Group Visits
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Osteogenesis Imperfecta
Study of Teriparatide (FORTEO) to Treat Adults With Osteogenesis Imperfecta
The purpose of this study is to determine the effectiveness of teriparatide (FORTEO), which is human parathyroid hormone 1-34, for increasing bone mass and improving bone structure in adults affected with Osteogenesis Imperfecta…
- Trial name
- OI (NCT00131469)
- Testing
- Teriparatide (FORTEO)
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Oregon Health and Science University
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Congenital Heart Disease, Single Ventricle
Diffuse Myocardial Fibrosis in Fontan Patients
The purpose of this protocol is to measure the relaxation of the heart in subjects with single ventricles who have undergone the surgical Fontan procedure.
- Conditions
- Congenital Heart Disease, Single Ventricle, Myocardial Fibrosis
- Trial name
- NCT01929174
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Oregon Health and Science University
Appendicitis
Pediatric Appendicitis Pathway Study
The purpose of this study is to test a standardized approach for children being evaluated for appendicitis in the emergency department.
- Trial name
- NCT01192620
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Oregon Health and Science University
Hypoglycemia
Effect of Hypoglycemia on Sleep
Growing evidence provided by many observational studies has established a strong link between decreased sleep duration and poor glucoregulation.
- Trial name
- NCT02687893
- Testing
- Aerobic Exercise, Resistance Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Gitelman Syndrome
A Translational Approach to Gitelman Syndrome
This study will test the response to a single dose of thiazide diuretic as a diagnostic test for Gitelman syndrome. Individuals with hypokalemic alkalosis will be enrolled.
- Trial name
- NCT00822107
- Testing
- Hydrochlorothiazide
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Oregon Health and Science University
Stroke, Cerebrovascular Accident
AMES Treatment of the Proximal Arm in Chronic Stroke
Subjects will receive 30 treatments with AMES, to the proximal arm which has been affected by a chronic stroke.
- Trial name
- AMES (NCT01934439)
- Testing
- 30 PAAD treatments
- Where
- United States
- Sponsor
- Oregon Health and Science University
Malnutrition
Trial of Continuous Versus Interrupted Feeding for Intubated Intensive Care Unit Patients
Surgical patients fed up until the point of surgery will have safe delivery of more calories compared to a group whose feeding is held at midnight prior to surgery.
- Trial name
- NCT01383980
- Testing
- Continuous Tube Feedings
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Oregon Health and Science University
Opioid Use Disorder, Alcohol Use Disorder
Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study
The purpose of this study is to learn how best to treat substance use disorders in an HIV clinic setting. Specifically, the purpose of this pilot study is to learn if extended-release naltrexone (XR-NTX) would be a feasible and…
- Trial name
- CHOICES (NCT01908062)
- Testing
- Extended Release Naltrexone, Treatment As usual
- Where
- 2 sites in United States, Canada
- Volunteers
- 51 people
- Sponsor
- Oregon Health and Science University
Chronic Disease
Post Affordable Care Act Evaluation
This innovative study will measure the impact of Affordable Care Act-sponsored Medicaid expansions on access to and utilization of community health center (CHC) services.
- Trial name
- PACE (NCT02657499)
- Testing
- Medicaid Expansion
- Where
- United States
- Volunteers
- 1,939,848 people
- Sponsor
- Oregon Health and Science University
Pelvic Organ Prolapse, Urinary Tract Infections
Study to Assess Duration of Indwelling Catheter After Sacrocolpopexy
Objectives The objective of this study is to help identify the best practice regarding the use of indwelling catheter after minimally invasive urogynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Urinary Tract Infections, Urinary Retention
- Trial name
- CARESS (NCT02189291)
- Testing
- Immediate catheter removal, Post op day 1 catheter removal
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Multiple Myeloma, Heart Failure, Systolic
Evaluation of Cardiotoxic Effects of Bortezomib
The purpose of this study is to learn more about how a drug commonly used to treat multiple myeloma can affect the heart. In this study, the investigators will learn whether a drug called how a drug (called bortezomib, or…
- Conditions
- Multiple Myeloma, Heart Failure, Systolic, Cardiotoxins
- Trial name
- NCT02026505
- Testing
- Bortezomib
- Volunteers
- 11 people
- Sponsor
- Oregon Health and Science University
Stress, Physiological, Stress, Psychological
Meditation or Health & Wellness Education Via Internet for Adults 50-80 Years Old
1. Telephone Eligibility Screening 2. Baseline Visit, includes online questionnaires, physical measures, cognitive tasks, voice recordings, physical recordings of brain waves, heart rate, breathing rate, and sweat during computer…
- Trial name
- NCT02467660
- Testing
- Mindfulness Meditation, Health & Wellness Education
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Deep Vein Thrombosis (DVT), Blood Clots
Below Knee DVT Study
Hospitalized patients are at risk of developing blood clots in the legs (Deep Vein Thrombosis or DVT), which can lead to death if those clots break off and migrate to the lungs.
- Trial name
- NCT03805672
- Testing
- Low Dose Enoxaparin, High Dose Enoxaparin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Oregon Health and Science University
Methamphetamine Abuse, HIV
Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade
The purpose of this protocol is to learn more about impulsive decision making in people who use methamphetamines. The investigators would like to know if a medication called naltrexone changes how people make decisions.
- Trial name
- NCT01822132
- Testing
- Extended release naltrexone
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Oregon Health and Science University
Heart Failure
LV Dysfunction Following Pacemaker Placement
Several studies have confirmed the link between chronic RV apical pacing and the development of heart failure and LV systolic dysfunction in some patients 1,2.
- Trial name
- NCT03850808
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Respiratory Compliance, Functional Residual Capacity
Rescue Antenatal Steroids and Pulmonary Function Tests in Preterm Infants
One course of steroids given to a mother before a premature delivery helps the lungs of the premature infant and decreases breathing problems.
- Conditions
- Respiratory Compliance, Functional Residual Capacity, Pulmonary Function Testing
- Trial name
- NCT00669383
- Testing
- betamethasone
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University