Clinical trials: sponsored by Oregon Health and Science University
Uveitis
Abatacept in the Treatment of Uveitis
The purpose of this study is to assess the safety and efficacy of abatacept in the treatment of uveitis.
- Trial name
- NCT01279954
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Afib, Hypertension
Combined Afib Ablation and RA Denervation for the Maintenance of Sinus Rhythm and Management of Resistant Hypertension
The purpose of this study is to perform renal artery denervation at the same time as atrial fibrillation ablation. RA denervation may reduce blood pressure, increase the chances of a successful atrial fibrillation ablation, and…
- Trial name
- NCT01952925
- Testing
- Renal Artery denervation
- Where
- United States
- Sponsor
- Oregon Health and Science University
Hemophilia, Elbow Joint Contracture
Efficacy of Strength Training in Improving Elbow Range of Motion and Function in Adults With Hemophilia
This is a research study of adults with hemophilia that have limitations in elbow joint motion that is the result of bleeding into the joint.
- Trial name
- NCT03842605
- Testing
- Strength training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Down Syndrome
Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
This is a research study of persons with Down Syndrome between 2 and 80 years old who are independently walking. The purpose of this study is to see what effect orthotics have on how people with Down Syndrome walk.
- Trial name
- NCT01390558
- Testing
- custom orthotics
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Oregon Health and Science University
Uveitis, Cystoid Macular Edema
Posterior Subtenon Versus Intravitreal Injection of Triamcinolone Acetonide for Treatment of Uveitic Cystoid Macular Edema
Macular edema is the most common sight threatening complication of uveitis which can lead to permanent loss of central vision. Triamcinolone acetonide ( the study drug)injection for treatment of cystoid macular edema(CME) is well…
- Trial name
- NCT02598869
- Testing
- Triamcinolone Acetonide
- Sponsor
- Oregon Health and Science University
Corneal Opacity, Keratoconus
OCT-guided LALAK for KCN
The purpose of this study is to determine if a new procedure, called laser-assisted lamellar anterior keratoplasty (LALAK), can achieve the same level of vision with a lower risk of potential complications after surgery compared…
- Trial name
- NCT01901614
- Testing
- LALAK, IEK, Retrobulbar Block or General Anesthesia
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Oregon Health and Science University
Contraception
Early Postpartum Intrauterine Device (IUD) Placement
Women who have just given birth are at high risk for rapid repeat pregnancy, which can lead to negative consequences during the subsequent pregnancy.
- Trial name
- NCT01594476
- Testing
- Levonorgestrel IUS
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Migraine Headache
Low-dose Propofol for Pediatric Migraine
Propofol, a general anesthetic, has been suggested to be effective for the treatment of migraine headaches in adults when used in subanesthetic doses (lower doses than those used for anesthesia or sedation).
- Trial name
- NCT01604785
- Testing
- Propofol, Standard Treatment
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Oregon Health and Science University
Aging
Mindfulness Meditation in Chronic Stress
The study purpose is to evaluate efficacy of a mindfulness training intervention and learn about cognitive and physiological markers of stress.
- Trial name
- NCT01386060
- Testing
- Mindfulness Meditation Training
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Low Dose Apomorphine and Parkinsonism
The purpose of this study is to determine if low doses of apomorphine worsen the motor symptoms of Parkinson's disease.
- Trial name
- NCT00472355
- Testing
- apomorphine
- Where
- United States
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Methylphenidate and Parkinson's Disease
The purpose of this trial is to determine if methylphenidate (MPD), a drug marketed in the U.S. to treat hyperactivity and narcolepsy, added to levodopa, will increase the beneficial effects of levodopa without bothersome side…
- Trial name
- NCT00359723
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Obesity, Weight Gain
Whole Body Vibration Training for Healthy Body Composition in Young Adults
The purpose of this study is to evaluate the benefits and feasibility of a whole body vibration (WBV) exercise program as a method of preventing weight gain in young adults.
- Trial name
- NCT02134275
- Testing
- Whole body vibration training, Control group
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Thyroid Hormone for Remyelination in Multiple Sclerosis (MS): A Safety and Dose Finding Study
This is a phase 1 study evaluating the safety and maximum tolerated dose of Liothyronine (T3) in subjects with multiple sclerosis
- Trial name
- MST3K (NCT02760056)
- Testing
- Liothyronine sodium
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Comparison of Continuous and Pulsatile Apomorphine in Parkinson's Disease
The purpose of this study is to compare the effects of apomorphine, given by two different methods, to determine how best to manage dyskinesias.
- Trial name
- NCT00758368
- Testing
- Apomorphine
- Where
- United States
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Frontal Cortex and Gait Freezing in Parkinson's Disease: Rehabilitation Impact
This project will relate our new quantification of Freezing of Gait (FoG) in Parkinson's disease, using body worn inertial sensors (Aim I), with abnormalities in state-of-the-art, resting state, functional brain connectivity (Aim…
- Trial name
- NCT02236286
- Testing
- Exercise
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Stress
Internet Mindfulness Meditation Intervention
Phase 1 will follow 40 subjects and hopes to address whether or not IMMI can increase meditation practice as compared to another meditation program.
- Trial name
- IMMI (NCT02655835)
- Testing
- Internet Mindfulness Meditation, Access
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Essential Tremor, Deep Brain Stimulation
The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients
The purpose of this study is to investigate the hypothesis that alternating DBS parameters on a weekly basis will prevent tolerance to stimulation and thus waning of benefit, compared with non-alternating stimulation.
- Trial name
- AltStim DBS (NCT02947841)
- Testing
- Alternating stimulation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Oregon Health and Science University
Bicuspid Aortic Valve
Bicuspid Valve Aortopathy Feasibility Study
In order to determine the effectiveness of medical therapy options to prevent enlargement of the aorta in patients with a bicuspid aortic valve, a randomized study will be planned.
- Trial name
- NCT01920815
- Testing
- No interventions
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes
Four Way Crossover Closed Loop With Exercise Detection
Closed-loop systems are an emerging technology that automate hormone delivery. They are quickly paving the way to revolutionize the treatment of type 1 diabetes.
- Trial name
- NCT02862730
- Testing
- Artificial Pancreas Controller in Dual Hormone Mode, Subject's insulin pump, Artificial Pancreas Controller in Single Hormone Mode
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Tecfidera and MRI for Brain Energy in MS
The primary objective of this study is to test the hypothesis that DMF can improve mitochondrial function in the brain of people with MS.
- Trial name
- NCT02644083
- Testing
- Dimethyl fumarate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Oregon Health and Science University