Clinical trials: sponsored by Oregon Health and Science University
STROMAL OPACITIES
LALAK for Opacities
The purpose of this protocol is to compare and develop new surgical technique of partial-thickness corneal transplantation for treating corneal opacity.
- Trial name
- NCT01901601
- Testing
- LALAK, IEK, Retrobulbar Block or General Anesthesia
- Sponsor
- Oregon Health and Science University
Diabetic Macular Edema
Pilot Study of OCT Versus Fluorescein Angiography in DME
Diabetic Macular Edema (DME), which can happen as a complication of diabetes, occurs when fluid and proteins collect in the macula (the yellow central area of the retina).
- Trial name
- OCT and DME (NCT01876914)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Non-exudative Age-related Macular Degeneration
Non-exudative Age-related Macular Degeneration
Age-related macular degeneration (AMD) is the most prevalent cause of vision loss in developed countries and is often discussed in terms of the "dry" and the "wet" forms.
- Trial name
- NEAMD (NCT01712841)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Neovascular Age-related Macular Degeneration
Neovascular Age-related Macular Degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in non-Hispanic white Americans. Neovascular AMD is an advanced form of macular degeneration that historically has accounted for the majority of vision loss…
- Trial name
- NVAMD (NCT01712035)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Oregon Health and Science University
Tethered Spinal Cord, Brain Tumor
Dexmedetomidine on Intraoperative Somatosensory and Motor Evoked Potential Monitoring During Neurosurgery in Pediatric Patients
The investigators want to know if using the study drug dexmedetomidine will improve nerve wave readings during neurosurgery. These readings are done many times during surgery while the patient is asleep.
- Conditions
- Tethered Spinal Cord, Brain Tumor, Cranio Cervical Compression
- Trial name
- NCT01512147
- Testing
- Isoflurane, Propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Methylphenidate to Improve Balance and Walking in MS
Methylphenidate is an amphetamine-like psychomotor stimulant drug currently approved for the treatment of attention-deficit hyperactivity disorder (ADHD), postural orthostasis tachycardia syndrome and narcolepsy.
- Trial name
- NCT01896700
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Intubation, Airway Management
Clinical Evaluation of the Storz CMAC Laryngoscope
This study aims to evaluate the utility of a video assisted device for intubation (placement of a breathing tube) during surgery.
- Trial name
- NCT00956592
- Testing
- CMAC video laryngoscope, Macintosh laryngoscope
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Measurements of Patients Using OCT Before and After LASIK
Corneal Power, Astigmatism, and Aberration Changes After LASIK
The primary goal of the study is to determine if Optical Coherence Tomography (OCT) measurement of corneal power and astigmatism is more accurate than conventional Placido-ring corneal topography.
- Trial name
- NCT01893671
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Quantification of the Antidyskinetic Effect of Amantadine and Topiramate in Parkinson's Disease
Levodopa is the main drug treatment for Parkinson's disease. Levodopa can cause unwanted and uncontrolled movements called dyskinesias. A drug called amantadine can reduce these movements.
- Trial name
- NCT00794313
- Testing
- Amantadine 300 mg, Topiramate, Sugar Pill
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Oregon Health and Science University
Coronary Artery Disease
Imaging and Omics for Cardiovascular Risk During NASA Deep Space Missions
The purpose of this study is to develop new approaches for screening astronauts for cardiovascular risk during deep space missions.
- Trial name
- NCT02465554
- Testing
- Myocardial contrast echocardiography
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Contraception, Maternal Care Patterns
Maternity Care and Contraception
This is a multicenter observational study of implementation of postpartum contraceptive counseling and provision into the maternity care setting in Colombia, South America.
- Conditions
- Contraception, Maternal Care Patterns, Pregnancy Related
- Trial name
- COMSE (NCT03389958)
- Testing
- Counseling and provision of contraception
- Where
- 3 sites in Colombia
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Difficult Airway
STorz Against Glidescope Effectiveness
This study evaluates success rates of tracheal intubation (passing a breathing tube)for patients who may be more challenging to intubate while utilizing one of two devices that facilitate placement of the tube with video…
- Trial name
- STAGE (NCT01632683)
- Testing
- C-MAC, Glidescope
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception, Body Weight
Emergency Contraception and Body Weight: Pilot Study
The purpose of this research study is to determine how body weight changes the drug level of an emergency contraceptive pill containing a hormone called levonorgestrel (LNG).
- Trial name
- NCT02408692
- Testing
- ECx1, ECx2
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
mTBI, Concussion
Quantification of Balance in Acutely Concussed Athletes
The purpose of this pilot project is to determine whether using inertial sensors placed on the waist during routine clinical balance testing (i.e.
- Conditions
- mTBI, Concussion, Mild Traumatic Brain Injury
- Trial name
- NCT01661075
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
COPE-Co-morbidities, Parkinson's Disease and Exercise
Problems with balance and walking that affect mobility are an inevitable cause of decreased quality of life in older people with chronic neurologic conditions such as Parkinson's disease (PD).
- Trial name
- COPE (NCT01361724)
- Testing
- Physical therapy, Group Exercise Class, Home Program
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Oregon Health and Science University
Tobacco Smoking
Behavioral Interventions to Target Self-Control
Low self-control has been associated with a number of unhealthy behaviors with low treatment success. Alternative non-pharmacological approaches have the potential for enhancing self-control.
- Trial name
- NCT02281942
- Testing
- Yoga, Education
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Dysphagia, Aspiration
Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft
Type I laryngeal cleft evaluation and treatment in the pediatric population is an emerging science. The largest published series of pediatric patients with type I laryngeal clefts shows conflicting evidence in terms of outcomes…
- Conditions
- Dysphagia, Aspiration, Quality of Life
- Trial name
- NCT01507207
- Testing
- Injection laryngoplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Urinary Incontinence, Urge
Examining Bladder Control Using Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI)
Urgency incontinence (where the bladder muscles contract suddenly, causing an immediate urge to urinate that is difficult to prevent) is commonly experienced in patients with overactive bladder.
- Trial name
- NCT01110278
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Blood Loss, Anesthesia
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures
Sevoflurane is an FDA-approved anesthetic drug commonly used for anesthesia during second trimester abortion procedures. It has a few advantages, including ease of use by the anesthesia provider.
- Trial name
- NCT01048658
- Testing
- Sevoflurane, No Sevoflurane
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain
Lidocaine and Pain Management in First Trimester Abortions
The purpose of this study is to examine the effect of lidocaine (a numbing medication) inside the uterus on patient pain during an early abortion, compared to the paracervical block (lidocaine injected on either side of the…
- Trial name
- NCT00613821
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University