Clinical trials: sponsored by Oregon Health and Science University
Contraceptive Usage, Vaginal Epithelial Disruption
Hormonal Contraception and Vaginal Health
The purpose of this study is to help determine if the route by which women receive hormonal contraception causes different changes to occur in the lining of the vagina.
- Trial name
- NCT00612508
- Testing
- Desogen (ethinyl estradiol and desogestrel), NuvaRing (ethinyl estradiol and etonogestrel)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
A Study of the Pharmacokinetics and Immunologic Effects of Lipoic Acid in Multiple Sclerosis
The purpose of this study is to learn about an investigational drug known as oral lipoic acid (LA) that may help treat multiple sclerosis.
- Trial name
- NCT00676156
- Testing
- oral lipoic acid (LA), lipoic acid (LA) with fish oil and LA without fish oil, R lipoic acid
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Depression
Study of Pathways Curriculum for Use With WPD
Study to assess the efficacy of a modified Pathways curriculum in treating depressive symptoms in women with physical disabilities.
- Trial name
- NCT00788814
- Testing
- Pathways
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oregon Health and Science University
Depressive Symptoms
Group Therapy Program for Women With Physical Disabilities
More women with disabilities (30%) report "feelings such as sadness, unhappiness, or depression that prevent them from being active" compared to women without disabilities (8%).
- Trial name
- CBT-WPD (NCT00618566)
- Testing
- WPD and Depression Treatment Group
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Oregon Health and Science University
Hydrocephalus
Study of Ultrasound of the Eye for Children With Suspected Shunt Failure
The purpose of the study is to determine whether an ultrasound of the eye can be used as a radiation-free alternative to X-ray to identify children with risk of shunt failure in the Emergency Department.
- Trial name
- NCT00743457
- Testing
- Ocular Ultrasound
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Oregon Health and Science University
Contraception
Immediate Versus Delayed Intrauterine Device (IUD) Insertion Following First Trimester Suction Aspiration Procedures
The purpose of this multi-center clinical trial is to evaluate the safety and effectiveness of inserting an intrauterine device (IUD) immediately after a suction aspiration procedure compared to inserting the IUD 2-6 weeks after…
- Trial name
- PAIR (NCT00562276)
- Testing
- Immediate IUD insertion
- Where
- 3 sites in United States
- Volunteers
- 578 people
- Sponsor
- Oregon Health and Science University
Cervical Pain, Pelvic Pain
The Effect of Nitroprusside on Intrauterine Device (IUD) Insertion
Increasing accessibility of long-acting reversible contraceptive methods, like intrauterine devices (IUDs), is an important strategy to reduce the risk of unintended pregnancy.
- Trial name
- NCT01248091
- Testing
- Nitroprusside Gel
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Inflammation, Pain
Efficacy of Tart Cherry Juice in Reducing Muscle Injury and Biomarkers of Muscle Damage Among Healthy Adults
The purpose of this study is to assess the effects of tart cherry juice to reduce serum biomarkers of inflammation and reduce muscle soreness in healthy adults who undergo a bout of controlled eccentric exercise.
- Trial name
- NCT01547949
- Testing
- tart cultivar Montmorency cherry juice
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Brain Concussion, Traumatic Brain Injury
Balance and Mild Traumatic Brain Injury (TBI)
The purpose of this pilot project is to determine whether using one inertial sensor on the waist during routine clinical balance testing (i.e.
- Trial name
- NCT01377454
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Appendicitis
Comparative Study of Laparoscopic Versus Open Appendectomy in Children
The study intends to compare the results of two surgical methods to remove the appendix in children with appendicitis. Specifically, up to 500 children over 3 years will be placed in two groups where the only difference in…
- Trial name
- NCT00554008
- Testing
- laparoscopic appendectomy, open appendectomy
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Oregon Health and Science University
Obesity
Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin
The purpose of this study is to learn more about how diet affects the hormone ghrelin. Ghrelin is made in the stomach and causes appetite to increase.
- Trial name
- NCT00694512
- Testing
- Low fat diet, High fat diet, MCT diet
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Intubation, Endotracheal, Leak Pressure
Leak Pressure of Uncuffed Pediatric Endotracheal Tubes
Children and adults frequently need a 'breathing tube' when having anesthesia for surgery. The breathing tube is usually inserted after the anesthesia doctor puts a patient to sleep with medicine, so they do not feel the…
- Trial name
- NCT00968058
- Testing
- Leak Test Recording
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Growth Hormone Deficiency
Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates
Study hypothesis: Growth hormone (GH), through its generation of free 'bioavailable' insulin-like growth factor (IGF)-I, can improve insulin sensitivity in adults with GH deficiency.
- Trial name
- NCT00517062
- Testing
- Growth hormone (Genotropin)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Oregon Health and Science University
Uveitis
Adalimumab (Humira) in the Treatment of Refractory Non-infectious Uveitis
The purpose of this study is to assess the safety and efficacy of Adalimumab in uveitis.
- Trial name
- NCT00525902
- Testing
- Adalimumab
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
American Ginseng Treatment for Multiple Sclerosis Related Fatigue
This research project will determine the safety and tolerability of ginseng in subjects with MS and will gather preliminary data on the efficacy of ginseng vs placebo for the treatment of MS fatigue.
- Trial name
- NCT00754832
- Testing
- American ginseng extract HT-1001
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Oregon Health and Science University
Kidney Failure, Chronic, Growth Hormone Deficiency
A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood
Treatment with growth hormone (GH; a hormone made by the body that stimulates growth) has been shown to be helpful in treating children with chronic kidney disease who fail to grow.
- Trial name
- NCT00212758
- Testing
- Nutropin AQ
- Where
- 8 sites in United States
- Volunteers
- 17 people
- Sponsor
- Oregon Health and Science University
Obesity, Hyperlipidemia
Body Worlds 3 Nutrition Display
Primary Aim # 1: Determine the willingness of the public to participate in an intervention trial - NutritionQuest's Alive!TM - available in a public forum.
- Trial name
- NCT00669500
- Testing
- Lifestyle intervention
- Where
- United States
- Volunteers
- 3,188 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Eczema
Feasibility Study of Barrier Enhancement for Eczema Prevention
The purpose of this protocol is to determine the feasibility of doing larger follow-up studies examining whether emollients used from birth can prevent eczema in high-risk babies and to help investigators find out if emollients…
- Trial name
- BEEP (NCT01142999)
- Testing
- Sunflower oil, Control group, Aquaphor ointment
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Oregon Health and Science University
Macular Degeneration
A Study of Genetic and Environmental Factors and Their Effect on Response to Treatment With Lucentis (Ranibizumab) for Wet AMD
The purpose of this study is to understand whether genes or certain factors in the environment determine how eyes will respond to Lucentis (ranibizumab) treatment.
- Trial name
- NCT00469352
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Oregon Health and Science University
Age-Related Macular Degeneration
Combination Ranibizumab and Bromfenac for Neovascular Age-related Macular Degeneration
This open-label, randomized, Phase II research study will look to see whether an investigational treatment combining bromfenac ophthalmic drops with ranibizumab intravitreal injection is safe and effective for treating wet AMD as…
- Trial name
- NCT00805233
- Testing
- combination ranibizumab + bromfenac, ranibizumab injection alone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University