Clinical trials: sponsored by Oregon Health and Science University
Uveitis
A Clinical Trial of Infliximab for Uveitis
This project is designed to test the hypothesis that inhibition of binding between tumor necrosis factor alpha (TNF-alpha) and its receptors using Remicade (infliximab, chimeric mouse/human IgG1K monoclonal antibody directed…
- Trial name
- NCT00273390
- Testing
- Remicade (infliximab)
- Volunteers
- 32 people
- Sponsor
- Oregon Health and Science University
Rib Fracture, Flail Chest
Clinical Study of the U-Plate Fracture Repair System to Treat Rib Fractures
The purpose of this study is to gather information about a device used to help fix broken ribs. Hypothesis: Rib fracture repair with the U-plate system is clinically durable and safe for the indications of flail chest repair…
- Trial name
- NCT00556543
- Testing
- U-plate fracture repair system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Fibromyalgia
Testing Mestinon and Exercise in Fibromyalgia
The purpose of this trial was to test the combined and independent effects of 6 months of exercise and Mestinon in people with fibromyalgia.
- Trial name
- NCT00535587
- Testing
- Exercise, pyridostigmine, Placibo
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Oregon Health and Science University
Pain, Inflammation
Efficacy of Tart Cherry Juice to Reduce Pain and Inflammation Among Patients With Inflammatory Osteoarthritis
The purpose of this study is to assess the effects of tart cherry juice to reduce pain and inflammation among individuals with arthritis.
- Trial name
- NCT01073982
- Testing
- tart cultivar Montmorency cherry juice
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Chronic Rhinosinusitis
Determinants of Surgical Outcomes in Chronic Sinusitis
Chronic rhinosinusitis (CRS) is a common health condition in the United States resulting in more than 200,000 surgical procedures annually.
- Trial name
- NCT00799097
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- Oregon Health and Science University
Carnitine Palmitoyl Transferase Type 1A (CPT1A) Deficiency
Metabolic Consequences of CPT-1 Deficiency
The purpose of this study is to learn more about how long children with CPT-1 deficiency can wait between meals without developing low blood sugar or symptoms of low blood sugar.
- Trial name
- NCT00653666
- Testing
- Medically supervised fasting
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Oregon Health and Science University
Obesity
The Energy Balance Study
Very low carbohydrate diets and high-complex carbohydrate, low-fat diets are popular weight-loss methods in the United States. The purpose of the Energy Balance Study is to explore how extreme differences in diet affect eating…
- Trial name
- EBS (NCT01029483)
- Testing
- Low carbohydrate diet, High-carbohydrate ad libitum intervention, High carbohydrate diet-energy matched intervention
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Colonoscopy
A Trial Comparing Bowel Preparation and Patient Tolerability of Miralax Versus Golytely
Prior to colonoscopies, the colon is cleansed using a laxative. Golytely is approved by the FDA for this purpose. Another laxative, called MiraLax, is approved by the FDA to relieve constipation, but it is not approved…
- Trial name
- NCT00889655
- Testing
- Golytely (polyethylene glycol), MiraLax (polyethylene glycol 3350)
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Huntington Disease
Ursodiol in Huntington's Disease
The purpose of this study is to evaluate the safety of the drug ursodiol (ursodeoxycholic acid, UDCA) in people with Huntington's disease (HD) and to explore how the compound is processed by the body.
- Trial name
- UDCA-HD (NCT00514774)
- Testing
- ursodiol
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Oregon Health and Science University
Ultraviolet Rays, Motivation
A Motivational Enhancement Approach to Skin Cancer Prevention
The specific aims of this research are: Aim 1 - To describe the UV protection behaviors and beliefs of young adult patients in a dermatology clinic.
- Trial name
- NCT00705887
- Testing
- Brief Motivational Enhancement Intervention
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity, Addison's Disease
The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation
Replacing glucocorticoid in a dose dependent manner (including doses within the physiological range) to subjects with adrenal insufficiency will increase visceral fat accumulation independently of total fat mass.
- Trial name
- NCT00688987
- Testing
- Hydrocortisone, Isocaloric Diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Parkinson's Disease
Effects of a Dopamine Agonist on Pharmacodynamics of Levodopa in Parkinson's Disease
The purpose of this study is to determine whether there is a benefit to giving a dopamine agonist to a patient with Parkinson's disease who is already being treated with levodopa.
- Trial name
- DALI (NCT00666653)
- Testing
- pramipexole
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Liver Transplantation
Prophylactic Therapy for Cytomegalovirus in Liver Transplant Recipients
Null Hypothesis: There is no significant difference in the incidence of CMV infection when using oral valganciclovir or ganciclovir as prophylactic anti-viral therapy.
- Trial name
- NCT00364052
- Testing
- oral Valganciclovir vs oral Ganciclovir
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Pain
4% Intrauterine Lidocaine Infusion for Pain Management in First Trimester Abortions
Recent studies have investigated the use of local anesthetics (i.e. lidocaine, mepivacaine) to lessen the pain experienced with minor gynecologic procedures such as endometrial biopsy and office hysteroscopy.
- Trial name
- NCT00121329
- Testing
- Intrauterine lidocaine infusion 4%
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Breakthrough Bleeding
Continuous Oral Contraceptives (COCs): Are Bleeding Patterns Dependent on the Hormones Given?
While there may be a decrease in the total number of bleeding days women experience with continuous-dosed COCs (no menstrual withdrawal week), these regimens frequently result in an increased number of "breakthrough" or…
- Trial name
- NCT00120913
- Testing
- Birth control pills
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University