Clinical trials: sponsored by Oslo University Hospital
Clostridium Difficile Infection
Fecal Transplantation for Primary Clostridium Difficile Infection
In this randomized controlled trial the investigators want to compare the effect of one-time rectal instillation of fecal microbiota transplantation, compared to a ten-day antibiotic course for the treatment of primary…
- Trial name
- COLONIZE (NCT03796650)
- Testing
- Fecal microbiota transplantation, Vancomycin
- Where
- 18 sites in Norway
- Volunteers
- 104 people
- Sponsor
- Oslo University Hospital
Critical Care
Strengthening Hope After ICU Discharge
The goal of this clinical trial is to evaluate an interventional program that aims to strengthen hope in intensive care unit (ICU) patients in the rehabilitation phase.
- Trial name
- NCT06569901
- Testing
- Hope Intervention
- Where
- 3 sites in Norway
- Volunteers
- 75 people
- Sponsor
- Oslo University Hospital
Celiac Disease in Children, Nutritional Deficiency
Celiac Disease and Quality of Life in Children and Adolescents (CeliaQLife)
Celiac disease is a disorder commonly diagnosed during childhood. The treatment is a lifelong gluten-free diet. Both the condition and the diet can influence the children's physical and emotional well-being.
- Conditions
- Celiac Disease in Children, Nutritional Deficiency, Quality of Life
- Trial name
- CeliaQLife (NCT06568263)
- Where
- 2 sites in Norway
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Atrial Fibrillation, Stroke
Fibrosis, Inflammation and Brain Health in Atrial Fibrillation.
Protocol synopsis Sponsor: Oslo University Hospital Title: Fibrosis, inflammation and cerebral infarction in patients with atrial fibrillation Study Design: The study is an observational prospective study of atrial fibrillation…
- Trial name
- NOR-FIB2 (NCT03816865)
- Where
- 2 sites in Norway
- Volunteers
- 46 people
- Sponsor
- Oslo University Hospital
Covid19
The Norwegian Study of Nervous System Manifestations and Sequelae After COVID-19
Neurologic, neuropsychological and neuropsychiatric symptoms, signs and diagnoses are increasingly being reported in COVID-19 patients.
- Trial name
- NeuroCovid (NCT04576351)
- Testing
- Observation
- Where
- 15 sites in Norway
- Volunteers
- 175 people
- Sponsor
- Oslo University Hospital
Headache, Migraine
New-onset Severe Headache After Covid-19 Vaccine
Hypotheses: 1. Severe new-onset headache after Covid-19 vaccine occur in a minor subset of vaccinated individuals. 2. Immunological reactivity with activation of trigeminal nociceptors can be among the mechanisms in severe…
- Conditions
- Headache, Migraine, COVID-19
- Trial name
- CovaxHEAD (NCT05235776)
- Testing
- observation
- Where
- 10 sites in Norway
- Volunteers
- 63 people
- Sponsor
- Oslo University Hospital
Lisfranc Injury, Foot Sprain
Weight-bearing Diagnostics in Acute Lisfranc Injury: CT vs X-ray
A prospective, cohort study comparing weight-bearing computed tomography with weight-bearing radiography in patients with an acute Lisfranc injury.
- Trial name
- NCT05799807
- Testing
- Conservative treatment, Minimally invasive stabilization
- Where
- Norway
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Autism Spectrum Disorder
Intranasal Oxytocin in Youth With Autism
Growing evidence demonstrates the critical contribution of the neuropeptide oxytocin in the development and maintenance of autism, due to its role in social behaviour and learning processes.
- Trial name
- NCT05934812
- Testing
- Oxytocin nasal spray
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Oslo University Hospital
Self Harm, Personality Disorders
Extreme Challenges - Psychopathology & Treatment Experiences Among Severly Selfharming Inpatients in Norway
Patients who self-harm are a heterogeneous population. Outpatient treatments structured for borderline personality disorder are often recommended and hospitalization kept to a minimum.
- Conditions
- Self Harm, Personality Disorders, Psychosis, Developmental Disorder
- Trial name
- NCT03768674
- Testing
- Assessment of diagnoses, functioning and health services
- Where
- Norway
- Volunteers
- 1,640 people
- Sponsor
- Oslo University Hospital
Intestinal Pseudo-Obstruction, Short Bowel Syndrome
Improved Quality of Life in Children With Intestinal Failure
Children with intestinal failure have a lack of tolerance for food in the intestine. The children are dependent on intravenous nutrition over a long period of time period to ensure growth and development.
- Conditions
- Intestinal Pseudo-Obstruction, Short Bowel Syndrome, Malabsorption Syndrome Autoimmune Enteropathy, Bacterial Overgrowth
- Trial name
- NCT04981262
- Testing
- Stimulance
- Where
- Norway
- Volunteers
- 56 people
- Sponsor
- Oslo University Hospital
Laryngomalacia, Sleep Apnea, Obstructive
Laryngomalacia, Examinations and Quality of Life in Children Before and After Treatment With Follow-up After 1 Year
Laryngomalacia is the most frequent cause of stridor in children under 1 year. The airway obstruction generates turbulent airway flow and creates the characteristic high-frequency stridor sound.
- Conditions
- Laryngomalacia, Sleep Apnea, Obstructive, Sleep Apnea, Ear, Nose and Throat Disorder
- Trial name
- NCT06464757
- Where
- 2 sites in Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cystic Fibrosis in Children
Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis
The aim of the present study is to investigate the effect of probiotic supplementation on GI related quality of life, through a randomised placebo-controlled clinical trial.
- Trial name
- NCT06284577
- Testing
- Multistrain Probiotic
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Self-management, Feasibility Studies
Self-management Program for Patients in the Sub-acute Phase After Traumatic Injury - a Feasibility Study
The goal of this descriptive non-randomized feasibility study is to assess aspects of feasibility of the intervention arm in a planned full-scale randomized controlled trial testing the effectiveness of a self-management program…
- Conditions
- Self-management, Feasibility Studies, Spinal Cord Injuries, Brain Injuries
- Trial name
- SMS_trauma (NCT06093074)
- Testing
- self-management program after traumatic injuries
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Perioperative Propranolol During Prostatectomy to Decrease Cancer Recurrence
The purpose of this study is to assess the feasibility of conducting a larger randomized controlled trial to assess the efficacy of perioperative propranolol capsules compared with placebo capsules in decreasing recurrence of…
- Trial name
- PeP-RALP (NCT05679193)
- Testing
- Propranolol
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Prostate Cancer
The Long Term Effect of MRI Before Radical Prostatectomy.
A randomized clinical trial conducted by Oslo University Hospital between 2010 and 2012 included 438 patients with prostate cancer to the non-MRI group (216) or the MRI group (222) before robot-assisted radical prostatectomy…
- Trial name
- NCT06429878
- Testing
- Biparametric prostatic MRI
- Volunteers
- 438 people
- Sponsor
- Oslo University Hospital
Quality of Life, Adverse Effects
International Validation of the QLQ-OH17 for Oral Health
Assessment of oral and dental problems is seldom routine in clinical oncology, despite the potential negative impact of these problems on nutritional status, social function and quality of life (QoL).
- Conditions
- Quality of Life, Adverse Effects, Late Effects, Cancer
- Trial name
- QLQ-OH17 (NCT01724333)
- Where
- 14 sites in France, Germany and 8 more
- Volunteers
- 585 people
- Sponsor
- Oslo University Hospital
Inflammation, Acute Illness
Nicotinamide Riboside in Hospitalized Patients
Patients will receive oral nicotinamide riboside or placebo and clinical and paraclinical outcome will be determined
- Trial name
- NCT04110028
- Testing
- Nicotinamide riboside
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- Oslo University Hospital
Secondary Malignant Neoplasm of Liver, Colorectal Neoplasms
Oslo Randomized Laparoscopic Versus Open Liver Resection for Colorectal Metastases Study
The purpose of the study is to compare outcomes of laparoscopic versus open liver resection for colorectal metastases in a prospective and randomized study.
- Trial name
- Oslo-CoMet (NCT01516710)
- Testing
- Open liver resection, Laparoscopic liver resection
- Where
- Norway
- Volunteers
- 280 people
- Sponsor
- Oslo University Hospital
Dorsal Malunion of the Distal Radius
CaP Cement is Equivalent to Iliac Bone Graft in Filling of Large Metaphyseal Defects
CaP Cement is Equivalent to Iliac Bone Graft in Filling of Large Metaphyseal Defects
- Trial name
- NCT02827006
- Testing
- corrective osteotomy distal radius
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital