Clinical trials: sponsored by Oslo University Hospital
Liver Transplant; Complications, Transplant; Failure, Liver
Liver Transplantation After ex Vivo Liver Perfusion
Today, it is difficult to predict liver function after transplantation and therefore livers where poor function is assumed (marginal livers) become discarded.
- Conditions
- Liver Transplant; Complications, Transplant; Failure, Liver, Transplant Dysfunction, Transplant; Complication, Rejection
- Trial name
- EVOLVE (NCT05951231)
- Testing
- Liver transplantation
- Volunteers
- 22 people
- Sponsor
- Oslo University Hospital
Epilepsy
Does Pulse-triggered VNS Autostimulation Increase VNS Efficacy
This is a research study to investigate whether the use of an extra function of vagus nerve stimulator (VNS) can give an improved effect against epilepsy. Many epileptic seizures are accompanied by an increase in heart rate.
- Trial name
- ERAS (NCT04095247)
- Testing
- Vagus nerv stimulator
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Oslo University Hospital
Brain Metastases
Improved Therapy Response Assessment in Metastatic Brain Tumors
TREATMENT is an observational study addressing the need for knowledge and adequate diagnostic biomarkers in the response assessment of patients with brain metastasis.
- Trial name
- TREATMENT (NCT03458455)
- Testing
- Magnetic Resonance Imaging, Stereotactic Radiosurgery, Ipilimumab, nivolumab or pembrolizumab
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Epilepsy, Temporal Lobe
Epilepsy Surgery and Cognitive Outcome
This study will give important information about long term consequences of temporal lobe epilepsy surgery on cognition (memory, language, concentration etc), psychiatric function and quality of life.
- Trial name
- NCT04264780
- Testing
- Neuropsychological examination
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Oslo University Hospital
Intentional Self Harm
Long Term Efficacy of DBT-A in Adolescents With Repetitive Self-harming and Suicidal Behaviours
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT01593202
- Testing
- Dialectical behavior therapy, Enhanced usual care
- Where
- Norway
- Volunteers
- 77 people
- Sponsor
- Oslo University Hospital
Lymphoma, Follicular
Mosunetuzumab for Early Relapse of Follicular Lymphoma in the Nordic Countries
In this clinical trial adult patients diagnosed with follicular lymphoma and relapse or progression of disease within 24 months of starting first line treatment will be treated with mosunetuzumab.
- Trial name
- MERLIN (NCT05849857)
- Testing
- Mosunetuzumab
- Where
- 3 sites in Finland, Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Critical Illness, Discomfort
Discomfort in Intensive Care Patients - IPREA-N
The purpose of this study is to investigate discomforts experienced by intensive care patients during their critical illness period.
- Trial name
- NCT06091046
- Volunteers
- 250 people
- Sponsor
- Oslo University Hospital
Stroke, Acute
Optimizing Acute Ischemic Stroke Diagnostics Using Artificial Intelligence
Prospective observational multi-center study with the aim to organise and simplify the care pathway through a pragmatic approach to acute stroke imaging powered by cutting edge advances in image processing and artificial…
- Trial name
- AI-STROKE (NCT05652933)
- Testing
- Software for identifying vessel occlusion, infarct volume and penumbra
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Influenza A, Pandemic Influenza
H7HLAII DNA Influenza Vaccine
The purpose of this study is to assess safety and immunogenicity of H7HLAII, a DNA vaccine encoding influenza hemagglutinin (HA) from influenza A/Shanghai/2/2013 (H7N9) directed to cells expressing human leukocyte antigen class…
- Trial name
- H7N9vax-1 (NCT06046092)
- Testing
- H7HLAII
- Where
- Norway
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Congenital Heart Disease
Theophylline Effects in the Fontan Circulation
A single group treatment phase 2 single-arm no-masking study to assess safety and efficacy of a short-term oral treatment with theophylline (ATC-no.
- Trial name
- THIEF (NCT05717049)
- Testing
- Theophylline Tablets
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Angina Pectoris
Myocardial Ischemia After Coronary Sinus Reduction Stent Implantation
Chronic angina pectoris refractory to medical and revascularization therapies is a disabling medical condition and a major public health problem. Patients with refractory angina have limited treatment options.
- Trial name
- MICS-Reduce (NCT06033495)
- Testing
- Coronary sinus reduction stent
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Peripheral Neuropathic Pain, Radiculopathy
Burst Spinal Cord Stimulation for Neuropathic Pain.
This study will evaluate the effect of Burst spinal cord stimulation (SCS) in the treatment of painful radiculopathy in lower extremity(ies) with or without lower back pain.
- Conditions
- Peripheral Neuropathic Pain, Radiculopathy, Lower Back Pain
- Trial name
- NCT03733886
- Testing
- Burst SCS (Abbott Proclaim IPG and single lead Abbott Octrode at level Th9/10)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Feeding and Eating Disorders, Diabetes Mellitus, Type 1
Effectiveness of the Diabetes Body Project Among Females With Type 1 Diabetes
Young females with type 1 diabetes (T1D) is at high risk of eating disorders (ED), with prevalence rates of ED more than double those of non-diabetes peers.
- Conditions
- Feeding and Eating Disorders, Diabetes Mellitus, Type 1, Body Image
- Trial name
- DBP (NCT04837989)
- Testing
- Diabetes Body Project, Psychoeducation
- Where
- Norway
- Volunteers
- 58 people
- Sponsor
- Oslo University Hospital
Myocarditis
Covid-19 Vaccine Associated Myocarditis and Pericarditis in Norway
This is a national multicenter study in Norway investigating of individuals with Covid-19 vaccine associated myocarditis (VAM) and pericarditis in Norway.
- Trial name
- NCT05610423
- Testing
- no intervention
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Knee Outcome, Subjective
Double Bundle Anterior Cruciate Ligament Reconstruction
There has been an increased awareness towards ACL (anterior cruciate ligament) injuries for Norwegian teams, particularly in handball and soccer.
- Trial name
- NCT01033188
- Testing
- Single bundle, Double bundle
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Depression, Anxiety
A Comprehensive Wellness Program (SKY) to Mitigate Physician Burnout
The primary objective of the study was to determine whether the yoga-based breathing and meditation program SKY could improve wellness indicators in currently practicing physicians.
- Conditions
- Depression, Anxiety, Stress, Insomnia
- Trial name
- SKY (NCT05956470)
- Testing
- Meditation and breathing program : Sudarshan Kriya Yoga (SKY), Stress management education
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ankle Fractures
Intramedullary Nailing Versus Plate Fixation of Ankle Fractures. A Prospective, Randomized Controlled Trial.
The purpose of this study is to make a survey of functional outcome, radiological outcome and complication rate after intramedullary nailing (IMN) and plate fixation of Weber B ankle fractures in elderly patients, and contribute…
- Trial name
- NCT03377205
- Testing
- Compression screws and neutralization plate, Acumed Fibular Rod System
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Aortic Valve Stenosis, Left Ventricular Dysfunction
Better Patient Selection to Transcatheter Aortic Valve Implantation
This study evaluates whether a preoperative assessment of myocardial contractile reserve by tissue Doppler Imaging and myocardial fibrosis by cardiac magnetic resonance imaging (MRI) can enhance the patient selection and risk…
- Conditions
- Aortic Valve Stenosis, Left Ventricular Dysfunction, Myocardial Fibrosis
- Trial name
- NCT03107923
- Testing
- Dobutamine stress test
- Where
- 2 sites in Norway
- Volunteers
- 103 people
- Sponsor
- Oslo University Hospital
Aorto Iliac Occlusive Disease
Laparoscopic Surgical Treatment of Aorto-iliac Occlusive Disease
Patients with aorto-iliac occlusive disease (TASC, type D) operated with a totally laparoscopic aortobifemoral bypass operation and open aortobifemoral bypass operation will be followed up and the results will be compared between…
- Trial name
- LAS (NCT01259908)
- Testing
- Laparoscopic vs open Ygraft
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Gestational Diabetes, Cardiovascular Diseases
Gestational Diabetes Mellitus: "Placental-maternal Crosstalk and Future Health"
The GaP study is designed to close important knowledge gaps by: 1. exploring placental health and cellular ageing in GDM and the association with neonatal outcome 2.
- Conditions
- Gestational Diabetes, Cardiovascular Diseases, Placenta Diseases
- Trial name
- GaP (NCT05872009)
- Where
- Norway
- Volunteers
- 350 people
- Sponsor
- Oslo University Hospital