Clinical trials: sponsored by Oslo University Hospital
Malignant Melanoma
Trial of Vaccine Therapy With mRNA- Transfected Dendritic Cells in Patients With Advanced Malignant Melanoma
PRIMARY OBJECTIVES: Determination of safety and toxicity of vaccination with patients' tumour mRNA transfected DCs . SECONDARY OBJECTIVES:Determine immunological response to the vaccine (induction of specific T-cell response) and…
- Trial name
- NCT01278940
- Testing
- Dendritic Cells (DC) malignant melanoma, IL-2
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Atrial Fibrillation
FIRM as a Stand-alone Procedure in the Treatment of Atrial Fibrillation
The FIRM Study Oslo will in two sequential within-patient trials investigate the efficacy of focal impulse and rotor modulation (FIRM) as a stand-alone procedure in the treatment of paroxysmal and persistent atrial fibrillation…
- Trial name
- NCT02101541
- Testing
- FIRM ablation
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Oslo University Hospital
Electric Impedance, Human
Monitoring of Needle-placement With Multiple Frequency Bioimpedance Monitoring
A novel algorithm for bioimpedance measurements to detect nerve tissue, and discriminate it from other tissue types has been developed in a porcine model, by analysing a complex impedance dataset based on multiple measurement…
- Conditions
- Electric Impedance, Human, Hypodermic Needles, Tissues
- Trial name
- NCT02589899
- Testing
- Needle placement in different tissue types
- Where
- Norway
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Primary Hyperparathyroidism
Asymptomatic Primary Hyperparathyroidism: A Prospective, Randomized Trial
The present study is a randomized, controlled trial that investigates the effects of parathyroidectomy or medical observation in mild asymptomatic pHPT on morbidity and quality of life (QoL).
- Trial name
- SIPH (NCT00522028)
- Where
- Norway
- Volunteers
- 191 people
- Sponsor
- Oslo University Hospital
Food Hypersensitivity
Take Away Food Allergy; Inducing Tolerance in Children Allergic to Peanut
The purpose of the study is to identify prognostic markers and possible success rate of tolerance induction to peanut allergens in children allergic to peanut.
- Trial name
- NCT02457416
- Testing
- Peanut
- Where
- Norway
- Volunteers
- 77 people
- Sponsor
- Oslo University Hospital
Adolescent Chronic Fatigue Syndrome
Biopsychological Intervention in Chronic Fatigue Syndrome - a Pilot Study
This is a pilot study of a biopsychological intervention program for adolescent chronic fatigue syndrome. The program is related to cognitive behavioral therapy, which has been proven beneficial in this disorders, but includes…
- Trial name
- NCT02336126
- Testing
- Biopsychological intervention
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Aneurysmal Subarachnoid Hemorrhage
Transdermal Nicotine Replacement in Smokers With Acute Aneurysmal Subarachnoid Hemorrhage
All patients with acute aneurysmal hemorrhage are treated in accordance with our institutional protocol. After securing of the aneurysm, some smokers with acute aneurysmal hemorrhage are randomly assigned to transdermal nicotine…
- Trial name
- NRT-SAH (NCT02350335)
- Testing
- Nicotine (transdermal)
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Hearing Loss
Language Proficiency and Quality of Life After Receiving Cochlear Implantation as a Child
Treatment with cochlear implantation is now offered to proximately 95 % of children with deafness in Norway. More than 500 children have been operated at Oslo University Hospital.
- Trial name
- NCT01863875
- Where
- Norway
- Volunteers
- 530 people
- Sponsor
- Oslo University Hospital
Pain
Plexus Brachialis Block. Better to do by Start Than by End of Surgery?
The aim of the study is to find out if the timing of brachial plexus block, before or after surgery, has an impact of the extent of acute postoperative surgical pain or the incidence and severity of long-lasting (chronic) pain…
- Trial name
- NCT01740141
- Testing
- Plexus brachialis block
- Where
- Norway
- Volunteers
- 52 people
- Sponsor
- Oslo University Hospital
Heart Failure, Resynchronization Therapy
Acute Feedback on Left ventrIcular Lead Implantation Location for Cardiac Resynchronization Therapy
Exploratory, prospective, interventional, non-randomized single-center research study to compare metrics derived from 2 or 3-D reconstructions of lead movement, bioimpedance and VCG to augmentation of left ventricular…
- Conditions
- Heart Failure, Resynchronization Therapy, Assessment of Acute CRT Response
- Trial name
- CCI impact (NCT01996397)
- Testing
- Cardiac resynchronization therapy device implantation
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Post-transplant Diabetes Mellitus
GLP-1 Effects on Insulin and Glucagon in PTDM
Post-transplantation diabetes mellitus (PTDM) develops in 10-15 % of all renal transplant recipients within 10 weeks after transplantation, and has been associated with increased risk of cardiovascular disease and impaired…
- Trial name
- NCT02591849
- Testing
- Glucagon-like peptide-1 (GLP-1), Isotonic saline, Hyperglycemic clamp
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Proteinuria
Oral Paricalcitol in Renal Transplant Recipients for Reducing Albuminuria
The main objective of this study is to examine if paricalcitol may reduce progression of graft fibrosis and proteinuria in kidney transplant patients.
- Trial name
- NCT01694160
- Testing
- Paricalcitol
- Where
- Norway
- Volunteers
- 77 people
- Sponsor
- Oslo University Hospital
Pregnancy, Pain
Safety of Epidural Fentanyl and Adrenalin During Childbirth
Investigation of pharmacokinetic effects of combining fentanyl and adrenalin in the epidural solution given to women in childbirth
- Trial name
- NCT00685672
- Testing
- adrenalin
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Abdominal Aortic Aneurysm
Screening for Abdominal Aortic Aneurysm in 65 Year Old Males in Oslo
Male subjects, 65 years of age, living in Oslo, Norway will be invited to be screened for abdominal aortic aneurysm.
- Trial name
- AAAscreening (NCT01248533)
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Renal Failure
Effect of a Pre Heparin Coated Dialysis Filter on Coagulation During Hemodialysis
The purpose of this study is to determine whether the heparin-coated dialysis filter is superior to a conventional filter during hemodialysis in twelve stable, chronic hemodialysis (HD) patients.
- Trial name
- NCT01388270
- Testing
- a pre-heparin-coated hemodialysis filter; Hepran
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
Heart Transplant Recipients
Long Term Effect of High-intensity Training After Heart Transplantation
High-intensity training (HIT) has repeatedly been documented to have superior positive effects compared to moderate exercise in patients with coronary heart disease and heart failure.
- Trial name
- NCT02213770
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Oslo University Hospital
Chronic Low Back Pain
Lumbar Disc Prosthesis Versus Multidisciplinary Rehabilitation; 8-year Follow-up
During the past 25-30 years, surgery with total disc replacement (TDR) has become an option for a selection of patients with chronic low back pain (LBP) traditionally treated conservatively or operated on with spinal fusion.
- Trial name
- NCT01704677
- Testing
- Lumbar total disc replacement, Multidisciplinary rehabilitation
- Where
- Norway
- Volunteers
- 151 people
- Sponsor
- Oslo University Hospital
Disorder Related to Renal Transplantation
The Effects of Omega-3 Fatty Acids in Renal Transplantation
Omega-3 fatty acids are provided through dietary intake of fish and seafood. Several dietary supplements containing omega-3 fatty acids are also commercially available.
- Trial name
- ORENTRA (NCT01744067)
- Testing
- Omega-3 fatty acids
- Where
- 2 sites in Norway
- Volunteers
- 132 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease, Decision Making
Shared Decision-making: Effects on Cardiac Risk Factor Modification Behavior
Decision Aids (DA) to inform patients about health care options and help them to participate in their care choices are widely advocated.
- Trial name
- NCT00714935
- Testing
- Decision Counseling Program (DCP), Coronary Artery Disease Decision Aid
- Where
- 2 sites in Norway
- Volunteers
- 363 people
- Sponsor
- Oslo University Hospital
Cancer, Injury of Liver
Implementing Online Patient-Provider Communication Into Clinical Practice
This interdisciplinary, international collaboration study, including the the Norwegian Health Economy Administration (HELFO) will evaluate the effectiveness and real-world implementation of an online patient-provider…
- Conditions
- Cancer, Injury of Liver, Diabetes
- Trial name
- OPPC (NCT00971139)
- Testing
- Access to an OPPC service
- Where
- Norway
- Volunteers
- 199 people
- Sponsor
- Oslo University Hospital