Clinical trials: sponsored by Oslo University Hospital
Prosthesis-related Infections, Staphylococcal Infections
Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplasty
The number of patients requiring joint replacement is increasing due to its success in restoring function and pain relief, and the growing population of the elderly.
- Trial name
- NCT00423982
- Testing
- Rifampin-combination therapy, Monotherapy
- Where
- 8 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Constipation, Ileus
Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
This study investigated the effect of preoperative bowel preparations for patients undergoing spinal fusion surgery.
- Conditions
- Constipation, Ileus, Surgery
- Trial name
- NCT01879605
- Testing
- Docusate natrium and sorbitol, Bisacodyl
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Oslo University Hospital
Lymphoma
Effect of Interactive Tailored Assessment on Patient-provider Communication
This interdisciplinary international research collaboration will test effects of Choice, a computer-assisted, interactive support system designed to help cancer patients communicate their symptoms and preferences, and clinicians…
- Trial name
- NCT00857103
- Testing
- CHOICE
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Hearing Loss, Tinnitus
Hearing Impairment, Cognitive Therapy and Coping
A randomized controlled study with hearing impaired workers, who have voluntarily signed up for an 8 session cognitive therapy (CBT) course The CBT intervention will be compared to a waiting list control group.
- Conditions
- Hearing Loss, Tinnitus, Stress, Psychological, Mental Fatigue
- Trial name
- NCT01206829
- Testing
- 8-session CBTcourse, 8 session cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Cancer, Breast Cancer
Internet Support for Cancer Patients
Cancer patients often experience multiple physical, functional and psychosocial symptoms, but have limited support while being at home between treatments and during rehabilitation.
- Conditions
- Cancer, Breast Cancer, Prostate Cancer
- Trial name
- WebChoice (NCT00710658)
- Testing
- WebChoice
- Where
- Norway
- Volunteers
- 325 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease, Diabetes Mellitus, Type 2
Exercise Training in Patients With Coronary Heart Disease and Type 2 Diabetes
Diabetes mellitus (DM) is an important risk factor in the development of cardiovascular disease, and people with type 2 diabetes have a two- to four-fold increased risk for cardiovascular morbidity and mortality.
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Type 2, Atherosclerosis
- Trial name
- EXCADI (NCT01232608)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 137 people
- Sponsor
- Oslo University Hospital
Hyperglycemia, Normoglycemia
Skeletal Muscles, Myokines and Glucose Metabolism MYOGLU
Normal glucose uptake and metabolism in skeletal muscles are essential to keep blood glucose within normal range and hence, insulin resistance (possibly mediated by inflammatory processes) in skeletal muscle is a major pathogenic…
- Conditions
- Hyperglycemia, Normoglycemia, Myokine
- Trial name
- MyoGlu (NCT01803568)
- Testing
- Exercise
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hereditary Factor VIII Deficiency Disease With Inhibitor
A Comparison Study of Bypassing Agent Therapy With and Without Tranexamic Acid in Haemophilia A Patients With Inhibitor
Activated prothrombin complex concentrate (aPCC) and recombinant activated factor VII (rFVIIa) are the only two drugs that are available to treat bleeds in haemophilia A patients with high titer inhibitors.
- Trial name
- BPATXAS (NCT01800435)
- Testing
- aPCC, aPCC + TXA, rFVIIa, rFVIIa + TXA
- Where
- Norway
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Heart Transplantation
Effect of Exercise After Heart Transplantation
This is a randomized controlled trial which will include approximately 50 heart transplant recipients 1-8 years after heart transplantation. The intervention and follow up period is 1 year.
- Trial name
- TEX (NCT01091194)
- Testing
- Interval-based aerobic exercise
- Where
- Norway
- Volunteers
- 51 people
- Sponsor
- Oslo University Hospital
Recall Rate, Cancer Detection Rate
Tomosynthesis in the Oslo Breast Cancer Screening Program
The Digital Breast Tomosynthesis (DBT) in the Oslo Mammography Screening Program will include women aged 50 to 69 years invited to the population-based mammography-screening program.
- Conditions
- Recall Rate, Cancer Detection Rate, False Positive Rate, Positive Predictive Value
- Trial name
- DBT (NCT01248546)
- Testing
- Digital breast tomosynthesis
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hernia
CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair
The study aims to show variation in CA-125 and other inflammatory markers assumed to be a response to trauma and peritoneal inflammation in the perioperative period of laparoscopic ventral hernia repair
- Trial name
- NCT01323361
- Testing
- Laparoscopic ventral hernia repair
- Where
- 2 sites in Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Cystic Fibrosis
Study of Individualized Physiotherapy for Airway Clearance in Cystic Fibrosis.
The purpose of this study is to investigate individual efficacy in Physiotherapy for Airway Clearance, and to investigate user experience, i.e.utility value and preference.
- Trial name
- NCT01266473
- Testing
- Physiotherapy
- Volunteers
- 6 people
- Sponsor
- Oslo University Hospital
Hip Fracture
Nutritional Risk Factors for Hip Fracture: a Case Control Study
Low Body Mass Index (BMI) is a risk factor for hip fracture, but it is unknown if it is the low BMI per se that increases risk of hip fracture or if specific micro-nutrients contribute.
- Trial name
- NCT01738776
- Where
- Norway
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial
The purpose of this study IS to explore the underlying pathophysiology of chronic fatigue syndrome (CFS) in adolescents, particularly focusing on genetics, infections/immunology, endocrinology, autonomic control and cognitions to…
- Trial name
- NorCAPITAL (NCT01040429)
- Testing
- Clonidine, Lactose capsula
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Bronchiolitis
Bronchiolitis All-study, SE-Norway
Bronchiolitis is a common lower respiratory disease typically affecting infants and children generally younger than 2 years of age.
- Trial name
- NCT00817466
- Testing
- Racemic adrenaline, Isotonic saline
- Where
- 9 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
The Physical Exercise and Prostate Cancer Study
The purpose of this study is to determine the effectiveness of a four months strength training program on physical and psychological health in patients with prostate cancer during androgen deprivation therapy.
- Trial name
- PEPC (NCT00658229)
- Testing
- Strength training group
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Congenital Heart Defects
Outcomes in Patients and Their Closest Relatives Treated for Congenital Heart Disease With Catheter Based or Surgical Techniques
This study compares clinical, self- reported and cost outcomes in children and adolescents treated with pulmonary valve implantation, percutaneous versus open surgical technique.
- Trial name
- MEQC (NCT01421030)
- Testing
- Percutaneous pulmonary valve implantation or open heart surgery
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Celiac Disease, Gluten
HLA-DQ2-gliadin Tetramer for Diagnosis of Celiac Disease
The investigators will evaluate the use of an HLA-DQ2-gliadin tetramer for staining of gluten specific T cells in the diagnostics of uncertain celiac disease.
- Trial name
- NCT01100099
- Testing
- Gluten challenge.
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Liver Transplant
Albumin, Total and Free Fraction of Mycophenolic Acid, and Measurement of IMPDH Activity in Liver Transplants.
In this study we aim to investigate to what extent the serum albumin concentration in liver transplant patients treated with mycophenolic acid (MPA) affect the free fraction of MPA.
- Trial name
- Albumix (NCT00995956)
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Thromboembolism, Acute Lymphoblastic Leukemia
Thromboembolic Complications Related to Asparaginase in Children With Acute Lymphoblastic Leukemia (ALL) Treated According to NOPHO ALL 2008
The study will examine the prevalence of venous thromboembolism in children with acute lymphoblastic leukaemia treated in accordance with NOPHO ALL-2008.
- Trial name
- NCT00982514
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital