Clinical trials: completed, sponsored by Peking Union Medical College Hospital
Infection Control
Risk Assessment of Indirect Exposure to the Environment in the Gastrointestinal Endoscopy Center
Study objective: To clarify the risk of exposure to indirect contact and transmission of environmental objects during digestive endoscopy diagnosis and treatment for patients and medical staff, simulating by using Vitamin B2…
- Trial name
- NCT05321043
- Testing
- Vitamin B2 labeling
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Rare Disorders, Rare Diseases
Artificial Intelligence for General and Rare Disease Diagnosis
A multicentre, randomised diagnostic accuracy study to evaluate whether the GENESIS AI diagnostic support system can improve diagnostic accuracy and efficiency for physicians managing real-world clinical general and rare cases.
- Conditions
- Rare Disorders, Rare Diseases, Generalist AI
- Trial name
- NCT07625436
- Testing
- AI-Assisted Diagnosis
- Where
- 11 sites in China
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Postprandial Hypotension, Post-induction Hypotension
Correlation Between Postprandial Hypotension and Post-induction Hypotension in the Elderly.
Postprandial hypotension (PPH) and post-induction hypotension (PIH) are very common in the elderly population and are associated with a variety of poor outcomes.The purpose of this study is to investigate the correlation between…
- Trial name
- NCT05575661
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Peking Union Medical College Hospital
Langerhans Cell Histiocytosis
Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
Study Type: Interventional Study Design: Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment purpose: This single arm clinical trial is studying…
- Trial name
- MAALCH (NCT02389400)
- Testing
- methotrexate
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Peking Union Medical College Hospital
Esophageal Achalasia
Assessment of Different Modified POEM for Achalasia
The aims of this study is to compare the efficacy and safety of conventional myotomy (circular myotomy) and modified myotomy (full-thickness myotomy) in the treatment of achalasia patients.
- Trial name
- NCT04578769
- Testing
- conventional myotomy, full-thickness myotomy
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Peking Union Medical College Hospital
Esophagogastroduodenoscopy, Upper Gastrointestinal Bleeding (UGIB)
Effect of Ondansetron on Patient Tolerance, Efficacy and Endoscopist Workload in Unsedated Endoscopy for Upper Gastrointestinal Bleeding
The goal of this clinical trial is to evaluate whether intravenous ondansetron can improve patient tolerance and reduce discomfort during unsedated emergency esophagogastroduodenoscopy (EGD).
- Trial name
- NCT07336680
- Testing
- intravenous ondansetron
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Gut Microbiota, Postoperative Pulmonary Complications
Gut Microbiota and Pulmonary Complications After Non Cardiac Elective Surgery in Elderly Patients
An observational cohort was established using preoperatively collected biospecimens and prospectively ascertained postoperative outcomes.
- Trial name
- NCT06513416
- Testing
- Elective abdominal surgery
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Peking Union Medical College Hospital
Stroke, Acute, Educational Problems
Off-script Diagnosis & Differential Diagnosis (D&D) Training and Residents' Stroke Knowledge
This study is a single-center, randomized, open-label, controlled, endpoint-blinded study to assess the effect of off-script diagnosis \& differential diagnosis (D\&D) training in improving the residents' knowledge of acute…
- Conditions
- Stroke, Acute, Educational Problems, Clinical Course
- Trial name
- CAST-AIS (NCT06941753)
- Testing
- Off-script diagnosis & differential diagnosis (D&D) training
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hyperlipidemias
Effect of Omega-3 Supplementation on Fasting Triglycerides During Lifestyle Intervention in Adults With Mild-to-moderate Hypertriglyceridemia
Patients with hyperlipidemia will be allocated to the intervention or control group randomly. Participants of the intervention group will be provided with Omega-3 PUFA, while participants of the control group will be provided…
- Trial name
- NCT05015348
- Testing
- Omega-3 PUFA supplementation
- Where
- China
- Volunteers
- 127 people
- Sponsor
- Peking Union Medical College Hospital
Severe Checkpoint Inhibitor Pneumonitis
The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia
This study is a prospective multicenter randomized controlled Interventional study, to assess the clinical efficacy and safety of corticosteroids compared to corticosteroids in combination with Ruxolitinib in the treatment of…
- Trial name
- NCT05899725
- Testing
- Corticosteroids, Corticosteroids and Ruxolitinib
- Where
- 4 sites in China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Primary Aldosteronism, Primary Aldosteronism Due to Aldosterone Producing Adenoma
A Novel and Efficient Biochemical Screening Strategy for Glucocorticoid-Remediable Aldosteronism: Combined 1-mg Overnight Dexamethasone Suppression Test and Steroid Profile
This prospective observational study evaluates a simplified biochemical screening strategy to differentiate Glucocorticoid-Remediable Aldosteronism (GRA) from Aldosterone-Producing Adenoma (APA).
- Trial name
- NCT07700888
- Testing
- 1 mg overnight dexamethasone inhibition test
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Floor Rehabilitation Training
Development and Implementation of a Remote Monitoring and Feedback System for Female Pelvic Floor Rehabilitation Training Based on Artificial Intelligence
Pelvic Floor Rehabilitation Training Prescription Label: An individualized training prescription generated by aggregating a comprehensive profile of maternal information through AI and applying data deep-mining algorithms, aiming…
- Trial name
- NCT07697508
- Testing
- a remote monitoring and feedback system for female pelvic floor rehabilitation training based on artificial intelligence
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Continuous Glucose Monitoring
Effects of Intraoperative Glycemic Management Strategies Assisted With RT-CGM on TIR and Postoperative Recovery
The purpose of this study is to investigate the effect of intraoperative blood glucose management based on real-time continuous glucose monitoring ( RT-CGM) on time in range (TIR) and postoperative recovery during…
- Trial name
- NCT06755788
- Testing
- RT-CGM, Control
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Nausea and Vomiting
PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6
This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.
- Trial name
- NCT06241547
- Testing
- electrical stimualtion via EmeTerm bracelet, antimetic drugs（ dexamethasone，ondansetron）
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Uterine Cervical Neoplasm, Endometrial Neoplasms
Optimal Margin Evaluation of Online Adaptive Radiotherapy for Postoperative Treatment of Endometrial and Cervical Cancer
Online adaptive radiotherapy has demonstrated to be feasible to reduce inter-fractional radiotherapy errors as it re-optimizes treatment plan every fraction.
- Trial name
- NCT05682950
- Testing
- online adaptive radiotherapy
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Peking Union Medical College Hospital
HIV-1-infection
Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection
The efficacy and safety of Biktarvy in Treatment-Naïve Late Presenters with HIV-1 Infection
- Trial name
- NCT04296695
- Testing
- B/F/TAF, TDF/3TC/EFV
- Where
- 5 sites in China
- Volunteers
- 202 people
- Sponsor
- Peking Union Medical College Hospital
Demoralization
Effects of a Five-Dimensional Intervention Program Based on Inner Strength on Demoralization Syndrome in Elderly Cancer Patients
From January 2025 to January 2026, a total of 66 elderly cancer patients with demoralization syndrome who were hospitalized in the Department of Internal Medicine at Peking Union Medical College Hospital were enrolled.
- Trial name
- NCT07625904
- Testing
- psychological support
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Acute Cholecystitis
CBD Wall-Thickness Adjusted ICG Microdosing for Fluorescence Cholangiography in Moderate-to-Severe Acute Cholecystitis: A Single-Center Prospective Study
This is a single-center prospective study designed to develop and validate an individualized, low-dose indocyanine green (ICG) protocol for near-infrared fluorescence cholangiography during emergency laparoscopic cholecystectomy…
- Trial name
- NCT07551388
- Testing
- Indocyanine Green (ICG) Fluorescence Cholangiography
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Peking Union Medical College Hospital
Branch Atheromatous Disease
Efficacy and Safety of Tirofiban for Patients With BAD (BRANT)
Branch atheromatous disease (BAD)-related stroke, characterized by subcortical single infarcts without severe stenosis of the large artery, but with a clear atherosclerotic mechanism, is now regarded as a separate stroke type.
- Trial name
- BRANT (NCT06037889)
- Testing
- Tirofiban, Aspirin tablet, Clopidogrel tablet
- Where
- 25 sites in China
- Volunteers
- 516 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Cancer
Vinegar-induced Collection of Duodenal Pancreatic Juice Via Endoscopic Ultrasound
The goal of this clinical trial is to learn about the feasibility of collecting pancreatic juice through duodenal aspiration by ultrasound endoscopy (EUS) for molecular marker testing after intraduodenal infusion of vinegar in…
- Trial name
- NCT05617872
- Testing
- Vinegar 20ml, Vinegar 40ml
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Peking Union Medical College Hospital