Clinical trials: sponsored by Peking University
Monogenic Diabetes, Hyperinsulinemia
Application of FreeStyle Libre 2 for Evaluating Glycemic Variability Characteristics in Patients With Extreme Glucose Metabolism Phenotypes
This cross-sectional study aims to further subdivide diabetes mellitus into more homogeneous subgroups by focusing on extreme glucose metabolism phenotypes, including monogenic diabetes with β cell dysfunction, hyperinsulinemia…
- Trial name
- NCT07564518
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Thrombosis, Cardiovascular Diseases
A Phase I SAD/MAD and Liver Effect Study of Vitalangio in Venous Thromboembolism Patients .
The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of a new drug, Vitalangio1, in healthy male and female volunteers aged 18 to 55 years old.
- Trial name
- NCT07618351
- Testing
- Experimental: Food effect group, Active Comparator: Multiple dose group
- Where
- China
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS
IASO207 Injection for Active Refractory Systemic Lupus Erythematosus (SLE)
This is a single-center, open-label, exploratory clinical study designed to evaluate the efficacy and safety of IASO207 Injection (in vivo CAR-T) in patients with active refractory systemic lupus erythematosus.
- Trial name
- NCT07617740
- Testing
- IASO207 Injection
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Peking University People's Hospital
AML, Refractory/Relapse Acute Myeloid Leukemia
Allogeneic CAR-T(CT0890B) in NKG2DL+ R/R AML
A Clinical Study to Investigate the Safety and Efficacy of CT0890B in Patients with Relapsed/Refractory Acute Myeloid Leukemia.
- Trial name
- NCT07617285
- Testing
- CAR-T cells chimeric antigen receptor T cells
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Peking University People's Hospital
Older Adults, Cognitive Impairment
Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive Impairment
Patients with cognitive decline are frequently comorbid with sleep disorders which may in turn aggravate cognitive decline. Sedative dose dexmedetomidine improved sleep quality but incresed bradycardia and hypotension; low dose…
- Conditions
- Older Adults, Cognitive Impairment, Sleep Disorders, Dexmedetomidine
- Trial name
- NCT07610343
- Testing
- Dexmedetomidine-esketamine combination
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Light, Anesthesia
Light and Anesthesia
The objective of this clinical trial is to investigate the effect of light exposure on sedation depth during general anesthesia.The primary research questions this study aims to address include: Does light condition affect the…
- Conditions
- Light, Anesthesia, Sedation
- Trial name
- NCT07517484
- Testing
- eye mask
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Peking University People's Hospital
Patellofemoral Pain
Mobile-Based Telerehabilitation With Sensors for Adherence and Efficacy in Chronic Patellofemoral Pain: A Randomized Controlled Trial
This study is a prospective, single-center trial involving 174 patients diagnosed with patellofemoral pain. The study adhered to ethical guidelines and obtained informed consent from all participants.
- Trial name
- NCT06651996
- Testing
- one session of face-to-face telerehabilitation tutorial (OST), Three session of face-to-face telerehabilitation tutorials (TST), Six session of face-to-face telerehabilitation tutorials (SST)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Peking University Third Hospital
Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion
Diagnostic Value of 68Ga-Pentixafor PET/CT in Adrenal Tumors With Aldosterone and Cortisol Cosecretion
The goal of this observational study is to evaluate the diagnostic accuracy of 68 68 Ga-Pentixafor-CXCR4 PET/CT in identifying the dominant side of hormone excess in adult patients (aged 18-80 years) with primary aldosteronism…
- Trial name
- NCT07605156
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University First Hospital
Spinal Muscular Atrophy (SMA)
Robot-assisted Training
The goal of this clinical trial is to evaluate the long-term effects of isokinetic rehabilitation training in patients with spinal muscular atrophy (SMA).
- Trial name
- NCT06648486
- Testing
- With the assistance of wearable isokinetic training robot （ 7 children with SMA type II）
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Third Hospital
Ankle Sprain, Hypermobility, Joint
Comparison of MBR + Suture Tape and MBR for CLAI : A Prospective Cohort Study
GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. Additional suture tape augmentation has been suggested to provide more strength and stability.
- Trial name
- NCT06897293
- Testing
- Modified Broström procedure + Suture tape augmentation operation, Modified Broström procedure operation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Peking University Third Hospital
Gastric Cancer
Iparomlimab Tolvorlimab as Neoadjuvant Immunotherapy for Locally Advanced Gastric Adenocarcinoma With Microsatellite Instability/Mismatch Repair Deficiency
Study Background 1. Clinical Rationale and Unmet Medical Need Gastric cancer is the 5th most common malignancy and the 3rd leading cause of cancer death worldwide.
- Trial name
- NCT07595523
- Testing
- Iparomlimab/Tuvonralimab (QL1706)
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
HR+/HER2- Breast Cancer
Abemaciclib Dose Escalation in Early High-Risk Breast Cancer Adjuvant Therapy
Abemaciclib combined with endocrine therapy has become one of the important adjuvant treatment regimens for patients with HR+/HER2- high-risk early breast cancer.
- Trial name
- ADES (NCT07599137)
- Testing
- Dose escalation
- Volunteers
- 86 people
- Sponsor
- Peking University Cancer Hospital & Institute
Postoperative Complications
Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits…
- Trial name
- NCT01884298
- Where
- China
- Sponsor
- Peking University First Hospital
Anesthesia
General Anesthetic Mode and Postoperative Complications
The relationship between anesthetic medication and postoperative major cardiac and cerebral complications will be studied using logistic regression model.
- Trial name
- NCT03335579
- Testing
- inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil
- Volunteers
- 50,000 people
- Sponsor
- Peking University First Hospital
Immune Thrombocytopenia
ATRA for Management of Primary ITP
A multicenter, randomized, double-blind placebo-controlled study to report the efficacy and safety of all-trans etinoic acid compared to placebo for the treatment of adults with corticosteriod-resistant/relapsed primary immune…
- Trial name
- NCT07597395
- Testing
- all-trans retinoic acid (ATRA)
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Peking University People's Hospital
Postoperative Pain
Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy
to compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy.
- Trial name
- NCT03288428
- Testing
- Nalbuphine, Morphine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Osteosarcoma, MTAP Deletion
the Exploration of MTAP Deletion in Osteosarcoma by Immunohistochemistry
MTAP deletion frequently occurs in osteosarcoma, and PRMT5 has been identified as a synthetic lethal target for cancers with homozygous deletion of the MTAP gene, making it a promising target for anti-tumor drug development.This…
- Conditions
- Osteosarcoma, MTAP Deletion, Immunohistochemistry
- Trial name
- NCT07593573
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Peripheral Artery Disease
The Value of Super-resolution Ultrasound Imaging for Peripheral Artery Disease
Peripheral artery disease (PAD) is a chronic atherosclerotic disorder characterized by stenosis or occlusion of the extracranial arteries distal to the aortic arch, most commonly affecting the lower extremities.
- Trial name
- NCT07374601
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Breast Cancer
Clinical Application of Vagus Nerve Stimulation Combined With Immunoregulatory T Cells in Alleviating Aromatase Inhibitor-Induced Pain
The goal of this clinical trial is to learn whether transcutaneous auricular vagus nerve stimulation, also called taVNS, can help relieve aromatase inhibitor-related joint and muscle pain in adult women with hormone…
- Conditions
- Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Breast Cancer, Pain Alleviation
- Trial name
- NCT07593365
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Peking University People's Hospital
Kidney Cancers
Clinical Application of CAIX-Targeted PET Imaging in Tumors
According to the 2020 global cancer statistics, renal carcinoma ranks as the fourteenth most common malignant tumor worldwide. In 2020, there were 431,288 new cases and 179,368 deaths from renal cancer, and both the incidence and…
- Trial name
- NCT07590310
- Testing
- Each patient will undergo 68Ga/18F-CAIX-LT-BCH PET/CT imaging, with an administered radioactive dose of approximately 0.05-0.1 mCi/kg.
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Peking University Cancer Hospital & Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.