Clinical trials: sponsored by Peking University
Stress, Emotional, Stress-related Mental Disorders
Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences
The study aims to examine the effectiveness of joint parent-adolescent intervention in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as measured by the…
- Conditions
- Stress, Emotional, Stress-related Mental Disorders, Adverse Childhood Experiences
- Trial name
- EASY-PEP (NCT06619821)
- Testing
- Emotiaonl skill enhancement, PCE promotion, Psychoeducation
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Systemic Lupus Erythematosus
Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter, Randomised, Placebo-controlled Trial
The management of active systemic lupus erythematosus (SLE) is challenging due to the heterogeneous nature of the disease and lack of specific treatment.
- Trial name
- NCT04077684
- Testing
- Interleukin-2
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Peking University People's Hospital
Night Work
Apples in Night Shift
Background: Emergency doctors face a highly stressful work environment during night shifts. Long-term night shift work can lead to sleep deprivation, fatigue accumulation, and disruption of the biological clock, which may affect…
- Trial name
- NCT06714422
- Testing
- apple group, no apple group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Osteosarcoma
Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma
To evaluate the clinical application value in bone marrow protection of Trilaciclib in the neoadjuvant treatment of stage II/III classic osteosarcoma in combination with pirarubicin and lobaplatin.
- Trial name
- NCT06714383
- Testing
- Trilaciclib, Pirarubicin, Lobaplatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University People's Hospital
Gastric Cancer
Adjuvant Chemotherapy With S-1 Plus Oxaliplatin Versus S-1 Alone in Locally Advanced Gastric Cancer
The purpose of the study is to evaluate the efficacy and safety of S-1 plus Oxaliplatin versus S-1 only as adjuvant chemotherapy after curative distal gastrectomy in patients with locally advanced gastric cancer.
- Trial name
- RESCUE-GC (NCT02867839)
- Testing
- Oxaliplatin plus S-1, S-1 only
- Where
- 15 sites in China
- Volunteers
- 29 people
- Sponsor
- Peking University Cancer Hospital & Institute
Elderly Patients, Major Surgery
Anesthesia-handover Checklist and Perioperative Outcomes in Elderly
With the increasing number of surgical cases, intraoperative handover of anesthesia care is common and inevitable. Verbal handover from one anesthesiologist to another during surgery are being used in many hospitals.
- Conditions
- Elderly Patients, Major Surgery, Anesthesia; Adverse Effect, Prevention
- Trial name
- NCT04377633
- Testing
- Oral handover, Checklist handover
- Where
- China
- Volunteers
- 1,421 people
- Sponsor
- Peking University First Hospital
Stress-related Problem, Stress, Emotional
Effects of Parent-Adolescent Joint I-Interventions for Adolescents with Adverse Childhood Experiences
The study aims to examine the effectiveness of internet-based Parent-Adolescent Joint Interventions in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as…
- Trial name
- EASY-PEP-i (NCT06650696)
- Testing
- PCE promotion, Psychoeducation, Emotiaonl skill enhancement
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Graft Failure, Stem Cell Transplant Complications
Modified Second Haplo-transplantation for Graft Failure
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. We previously reported encouraging results with a novel Flu/Cy regimen.
- Trial name
- NCT06512545
- Testing
- second allogeneic stem cell transplantation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Peking University People's Hospital
Emotion Regulation, Adverse Childhood Experience
Paired Emotion Reading Improves Emotion Regulation in Rural Children With ACE
The goal of this study is to explore the feasibility and effectiveness of the online Paired Emotion Reading Intervention (PERI) on the emotion regulation of rural children with adverse childhood experiences (ACE), as compared…
- Trial name
- NCT06505629
- Testing
- the online Paired Emotion Reading Intervention (PERI), the online Paired General Reading Intervention (PGRI)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University
Anxiety and Depression
Guided Narrative Technique After Coronavirus Outbreak Influencing Positive and Negative Emotions and Cognition for Children--A Randomized Controlled Trial
At the beginning of 2020, the COVID-19 broke out in Wuhan, raging across the country quickly afterwards. As a sudden public health emergency, this epidemic caused some stress reactions (including emotional, cognitive, and…
- Trial name
- NCT06708442
- Testing
- School-based CBT intervention, Guided Narrative Technique (GNT) Writing, Guided Narrative Technique (GNT) drawing
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Peking University
IVF
Immediate Versus Postponed Freeze-all Embryo Transfer in Hyperresponders
This is a multicenter, randomised controlled trial. The investigators plan to randomise 836 participants to the immediate FET or the postponed FET from the day of oocyte retrieval to the last day of that menstrual cycle in a 1:1…
- Trial name
- NCT05483270
- Testing
- the timing of embryo transfer in freeze-all cycles
- Where
- China
- Volunteers
- 845 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Collecting Duct Carcinoma
Study to Evaluate the Efficacy and Safety of Immunotherapy With Axitinib in Advanced Collecting Duct Carcinoma
This is a phase II trial to evaluate the efficacy and safety of immune checkpoint inhibitors in combination with axitinib for previously treated advanced collecting duct carcinoma.
- Trial name
- NCT06211114
- Testing
- PD-(L)1 inhibitor, Axitinib
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Lung Cancer, Non-Small Cell, Lung Infection
Radiolabelled Nectin-4 Targeted LMW Probe PET/CT in Patients With Lung Lesions
To evaluate the ability of [68Ga]N188 to detect nectin-4 overexpression in patients with lung lesions.
- Trial name
- NCT06648317
- Testing
- FDG-PET
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
Multiple Myeloma
Risk Stratification and MRD-driven Maintenance for MM After ASCT
This study evaluates the maintenance strategy based on risk stratification and MRD status after stem cell transplantation. This is a single-arm, multicenter, prospective study.
- Trial name
- NCT06697483
- Testing
- Daratumumab, Lenalidomide
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Neoplasms
68Ga-N188 PET/CT Imaging in Malignancy
The Nectin-4 protein belongs to the cell adhesion factors family and has a tissue-specific expression spectrum in normal human tissues.
- Trial name
- NCT05593107
- Testing
- [68Ga]N188
- Where
- China
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Prostate Cancer
Comparison of MRI AI-cTB Versus Routine cTB in Prostate Cancer Diagnosis: a Prospective Randomized Controlled Trial
The goal of this clinical trial is to compare the cancer detection rates of MRI artificial intelligence-guided cTB (AI-cTB) and routine cTB, and explore the added value of using AI for the guidance of cTB.
- Trial name
- NCT06362291
- Testing
- MRI-AI guided cognitive prostate targeted biopsy, Routine cognitive prostate targeted biopsy
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Peking University First Hospital
Carpal Tunnel Syndrome (CTS), Ultrasound
Ultrasound-based Artificial Intelligence for Classification of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is one of the most prevalent peripheral neuropathies, impacting approximately 4% of the general population. It is typically classified into three degrees: mild, moderate, and severe.
- Conditions
- Carpal Tunnel Syndrome (CTS), Ultrasound, Artificial Intelligence (AI)
- Trial name
- NCT06697392
- Testing
- ultrasound examination
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University People's Hospital
Triple Negative Breast Cancer
De-escalation of Neoadjuvant Chemotherapy Regimens With Immunotherapy Among TNBC
The traditional neoadjuvant therapy for triple negative breast cancer is based on anthracycline, paclitaxel and carboplatin. Nowadays, immunotherapy combined with chemotherapy has become a new standard treatment, which not only…
- Trial name
- NacTNBC (NCT06692725)
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Peking University People's Hospital
Cervical Intraepithelial Neoplasias
Research on the Application of Patient Navigation-based Management Model of Patients After LEEP
Cervical cancer poses a significant threat to women's health and is a crucial public health issue. Early detection and treatment of cervical lesions and standardized management have emerged as essential pillars in the Global…
- Trial name
- NCT06695871
- Testing
- Patient navigation-based health management
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Peking University People's Hospital
Rare Tumour
Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS
The objective of this Phase II, open-label, multicenter, non-randomised controlled clinical trial is to guide precision treatment for patients with rare tumours based on Patient-Derived Organoids/Next-Generation Sequencing drug…
- Trial name
- SPRING (NCT06692491)
- Testing
- Albumin-Bound Paclitaxel, Epirubicin, Gemcitabine
- Volunteers
- 200 people
- Sponsor
- Peking University Shenzhen Hospital
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