Clinical trials: sponsored by Peking University First Hospital
Carcinoma, Non-Small-Cell Lung, Surgery--Complications
Dexamethasone, Flurbiprofen Axetil and Delirium After Lung Cancer Surgery
Delirium is a common complication in elderly patients after surgery. And its occurrence is associated with worse outcomes. The causes of delirium are multifactorial but may include pain, stress response and inflammation.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Surgery--Complications, Dexamethasone, Flubiprofen Axetil
- Trial name
- NCT03200600
- Testing
- Dexamethasone, Normal saline, Flurbiprofen axetil
- Where
- 2 sites in China
- Volunteers
- 126 people
- Sponsor
- Peking University First Hospital
Acute Kidney Injury
Early Prediction of Acute Kidney Injury in High Risk Patients After Non-cardiac Surgery
Acute kidney injury (AKI) is a common complication after non-cardiac surgery with adverse short and long term morbidity and mortality.
- Trial name
- NCT03880110
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University First Hospital
Critical Ill Patients, Patients Needing Continuous Renal Replacement Therapy
Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients
CRRT patients are generally critical ill patients with unstable conditions, such as low blood pressure,severe SIRS,et al. Acute kidney injury(AKI)is especially prevalent,with even two or more organ failure.
- Trial name
- NCT02355873
- Testing
- AN69ST hemofilter, AN69 hemofilter
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Acute Coronary Syndrome
Follow up of Ticagrelor Treatment Patterns in Chinese Acute Coronary Syndromes Patients
This is a retrospective, observational, descriptive study which will include patients hospitalized for acute coronary syndrome (ACS) and treated with ticagrelor at discharge.
- Trial name
- NCT04861363
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Peking University First Hospital
Elderly, Surgery
Impact of Dexmedetomidine on Sleep Quality
Sleep disturbances frequently occur in elderly patients after major surgery; and their occurrence are associated with worse outcomes including increased incidence of delirium.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03117790
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Peking University First Hospital
Postoperative Complications
Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications
Postoperative pulmonary complications (PPCs) are major causes of postoperative morbidity, mortality, and prolonged hospital stay.The incidence of PPCs may be as high as 41% to 75% in high-risk patients.
- Trial name
- NCT02644876
- Testing
- Penehyclidine inhalation
- Where
- China
- Volunteers
- 864 people
- Sponsor
- Peking University First Hospital
Renal Cell Carcinoma
Observational Study of Camrelizumab Combined With Apatinib and Hyperfractionated Radiotherapy for Renal Cell Carcinoma
This trial will explore effectiveness and safety using the combination therapy of camrelizumab，apatinib and hyperfractionated radiotherapy in patients with renal cell carcinoma(RCC).
- Trial name
- NCT04609293
- Testing
- camrelizumab+apatinib+hyperfractionated radiotherapy
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Resting Energy Expenditure, Chronic Kidney Disease
Novel Equation for Estimating Resting Energy Expenditure
The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients.
- Trial name
- NCT03377413
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Immunotherapy, SBRT
Combination of Hyperfractionated Radiotherapy With Immunotherapy in Massive Tumors
This trial will explore effectiveness and safety using the combination therapy of camrelizumab and hyperfractionated radiotherapy in patients with massive tumor including non-small cell lung cancer, soft tissue sarcoma or…
- Conditions
- Immunotherapy, SBRT, Bulky Tumor
- Trial name
- NCT04587817
- Testing
- camrelizumab+hyperfractionated radiotherapy
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Breast Cancer, Neoadjuvant Therapy
Validation of the CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging Systems After PST of BC in China
Prognostic assessment after preoperative systemic therapy (PST) plays a vital role in breast cancer patients. The clinical-pathologic staging system incorporating estrogen receptor (ER)-negative disease and nuclear grade 3 tumor…
- Conditions
- Breast Cancer, Neoadjuvant Therapy, Neoplasm Staging, Estrogen Receptor
- Trial name
- NCT03437837
- Where
- 12 sites in China
- Volunteers
- 1,077 people
- Sponsor
- Peking University First Hospital
Peritonitis
Different Retraining Methods vs Usual Care on the Prevention of Peritonitis in Peritoneal Dialysis
To examine whether retraining via operation inspection or verbal education can reduce the risk for peritonitis in PD patients.
- Trial name
- NCT01621997
- Testing
- operation inspection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University First Hospital
Lung Cancer, Thoracic Surgery
Epidural Anesthesia-analgesia and Long-term Survival After Lung Cancer Surgery
Available studies suggest that regional anesthesia-analgesia may decrease the occurrence of recurrence/metastasis in patients after cancer surgery. However, evidences from prospective studies are still lacking.
- Conditions
- Lung Cancer, Thoracic Surgery, Anesthesia, Epidural, Neoplasm Recurrence, Local
- Trial name
- NCT02801409
- Testing
- General anesthesia alone, Combined epidural-general anesthesia
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University First Hospital
Prevalence
Epidemiological Study on Anemia and Iron Deficiency in Pregnancy in Medical Institutions in Some Areas of China
The purpose of this study is to describe the prevalence of anemia and iron deficiency in pregnancy through a multi-center, prospective follow-up study .
- Trial name
- NCT04486456
- Volunteers
- 20,000 people
- Sponsor
- Peking University First Hospital
Elderly, Malignant Tumor
Epidural Anesthesia-analgesia and Long-term Outcome
Surgical resection is one of the most important treatments for resectable cancer; on the other hand, cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly, Malignant Tumor, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03012945
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Elderly, Epidural Anesthesia
Anesthesia-analgesia Methods and Postoperative Delirium
Postoperative delirium is a common complication in elderly patients after surgery. Its occurrence is associated with worse outcomes. The pathophysiology of delirium remains poorly understood.
- Conditions
- Elderly, Epidural Anesthesia, General Anesthesia, Major Surgery
- Trial name
- NCT01661907
- Testing
- Combined Epi-GA/PCEA, GA/PCIA
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Peking University First Hospital
Penehyclidine, Postoperative Nausea and Vomiting
Penehyclidine and Postoperative Nausea and Vomiting After Bimaxillary Surgery
Postoperative nausea and vomiting (PONV) are common complications after surgery. Patients undergoing orthognathic surgery are reported to have a high rate of PONV, especially those undergoing bimaxillary surgery.
- Conditions
- Penehyclidine, Postoperative Nausea and Vomiting, Bimaxillar Surgery
- Trial name
- NCT04112771
- Testing
- Penehyclidine hydrochloride, No penehyclidine hydrochloride
- Where
- 2 sites in China
- Volunteers
- 243 people
- Sponsor
- Peking University First Hospital
Recurrence (Disease Attribute)
Combination Therapy Prevents the Relapse of RA
This trial aims to compare the cost effective and effect of preventing recurrence by different treatment of TFP and HCQ combined SSZ for remittent RA.
- Trial name
- NCT02320630
- Testing
- Entanercept, HCQ, MTX
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University First Hospital
Oxygen Saturation
Diagnostic Study of Huami Smart Wearable Device
This is a cross-sectional diagnostic study. In this study, wrist oxygen saturation (SwO2) will be measured by Huami smart wearable device, SpO2 of pulse oxygen saturation monitor with medical device registration certificate and…
- Trial name
- DSHWD (NCT04429906)
- Testing
- Huami smart wearable device
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
COVID-19
Efficacy and Safety of Anluohuaxian in the Treatment of Rehabilitation Patients With Corona Virus Disease 2019
To evaluate the efficacy and safety of Anluohuaxian in blocking the progression of pulmonary fibrosis and improving lung function in patients with COVID-19.
- Trial name
- NCT04334265
- Testing
- Anluohuaxian
- Where
- 9 sites in China
- Volunteers
- 750 people
- Sponsor
- Peking University First Hospital
COVID-19
Corona Virus Disease 2019 Patients Whose Nucleic Acids Changed From Negative to Positive
To investigate the mechanism, clinical outcome and therapeutic efficacy with favipiravir of Corona Virus Disease 2019 patients whose nucleic acids changed from negative to positive.
- Trial name
- NCT04333589
- Testing
- Favipiravir
- Where
- 8 sites in China
- Volunteers
- 210 people
- Sponsor
- Peking University First Hospital