Clinical trials: sponsored by Penn State University
Delirium, Delirium in Old Age
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
The goal of this step-wedge trial is to test the implementation of daily nurse screening for delirium in routine care and its impact on outcomes and complications in hospitalized older adults admitted to 6 general…
- Conditions
- Delirium, Delirium in Old Age, Delirium With Dementia, Delirium Superimposed on Dementia
- Trial name
- READI-SET-GO (NCT05915377)
- Testing
- READI-SET GO UB-CAM delirium screening into EHR
- Where
- 2 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- Penn State University
Cardiometabolic Risk Factors
SPICE UP MyPlate - Strategy for Promoting Intake of Delicious Healthful Dietary Patterns Based on MyPlate: A Pilot Study
The aim is to conduct a pilot study to assess the feasibility, acceptability and potential effectiveness of culinary focused nutrition education to promote increased adherence to the Dietary Guidelines for Americans compared to…
- Trial name
- NCT06890728
- Testing
- Culinary focused nutrition education, Standard low intensity nutrition education
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Penn State University
Amyotrophic Lateral Sclerosis
Assessing Perceptual Effects of Interactive Tasks
In this study, we will evaluate how solo, naive listeners perceive the speech of people with amyotrophic lateral sclerosis (ALS) and age-matched speakers produced across interactive and non-interactive contexts with an…
- Trial name
- NCT06828523
- Testing
- Listener judgements of speech produced in different tasks
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pre-exposure Prophylaxis
Information Seeking About Pre-exposure Prophylaxis
The goal of these two intervention studies is to test promising health communication messaging strategies most likely to enhance Black, Hispanic, and non-Hispanic White YMSM's (young men who have sex with men's) engagement with…
- Trial name
- NCT05728034
- Testing
- Injectable PrEP information, Oral PrEP information
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Penn State University
Perimenopausal Bone Loss
Prunes Preventing Bone Loss in Perimenopause
Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss…
- Trial name
- Prune-UP (NCT07120997)
- Testing
- Prunes, Calcium supplement, Vitamin D Supplement
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Penn State University
Depression, Selective Serotonin Reuptake Inhibitor
Impact of Depression on Thermoregulation
The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with…
- Trial name
- NCT06805851
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Penn State University
Literacy, Communication, Nonverbal
Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners
The goal of this clinical trial is to determine whether adding Integrated Decoding and Encoding instruction to the ALLSTAR literacy program improves reading outcomes for students with significant literacy and communication needs.
- Trial name
- NCT07384156
- Testing
- ALLSTAR
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Penn State University
Sleep, Pain
More Sleep: Pain Response to Longer Sleep
This study is being done to find out whether extending sleep for at least an hour per night, seven days a week, predicts a higher tolerance and a higher threshold for pain. This is a 21-day study.
- Trial name
- NCT05816434
- Testing
- Sleep extension
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular Diseases
The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
This study will examine the effect of a healthy diet containing cottonseed oil compared to healthy diets containing other commonly consumed plant oils on biomarkers of heart and metabolic health after 4 weeks.
- Trial name
- NCT06216678
- Testing
- Healthy Dietary Pattern with Cottonseed Oil, Healthy Dietary Pattern with Fatty Acid-Matched Plant Oils, Healthy Dietary Pattern with PUFA:SFA Ratio-Matched Plant Oil
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Penn State University
Aging
Identification of Critical Thermal Environments for Aged Adults
This study evaluates critical environmental limits (temperature and humidity) above which older adults are unable to effectively thermoregulate.
- Trial name
- NCT04284397
- Testing
- Low dose ASA, Control
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Penn State University
Gestational Weight Gain, Overweight and Obesity
Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0
The goal of this clinical trial is to see if the enhanced HMZ 2.0 intervention with new control system/digital platform to regulate gestational weight gain (GWG) and impact maternal-infant outcomes while collecting implementation…
- Conditions
- Gestational Weight Gain, Overweight and Obesity, Pregnancy, Energy Balance
- Trial name
- HMZ Two (NCT05807594)
- Testing
- HMZ 2.0 Intervention, Attention Control Intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Penn State University
Concussion (Diagnosis), Concussion Post Syndrome
Female Concussion Head Cooling
This research is being done to examine the benefits of a 28 day head cooling intervention on cognition, inflammation of the brain, sleep quality, menstrual symptom interaction, and mood in acutely concussed females.
- Conditions
- Concussion (Diagnosis), Concussion Post Syndrome, Concussion, Mild
- Trial name
- NCT07303933
- Testing
- Brain Cooling
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Penn State University
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Breast Cancer Female
Breast Cancer Screening in Ghana
This study is designed to test the feasibility of two intervention on promoting early screening for breast cancer in rural Ghana.
- Trial name
- NCT06362993
- Testing
- Bundling, MEGH
- Where
- Ghana
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Penn State University
Iron Deficiency Anemia
Iron Status, Maternal Depressive Symptoms, and Mother-child Interactions
This study aims to examine the relation between iron status and maternal-child interactions as well as maternal depressive symptoms in mothers from central Pennsylvania.
- Trial name
- IDinteract (NCT03944733)
- Testing
- Iron, Gelatin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Penn State University
Childhood Obesity, Self-regulation
ONE PATH: Optimizing Nutrition Education for Parents and Teachers for Healthy Growth
This proposal uses an innovative methodological framework, the multiphase optimization strategy (MOST), to design an effective and efficient responsive feeding (RF) intervention that promotes child appetite self-regulation among…
- Conditions
- Childhood Obesity, Self-regulation, Appetite Regulation
- Trial name
- ONE PATH (NCT03817021)
- Testing
- ECE Provider, Parent Intervention, Child intervention
- Where
- United States
- Volunteers
- 1,461 people, healthy volunteers welcome
- Sponsor
- Penn State University
Depressive Symptoms
Audio-based Mental Health Intervention Study
This is a study on an audio-based digital intervention designed to reduce symptoms of depression. Participants who experience at least moderate symptoms of depression will be invited to participate in the study.
- Trial name
- NCT05555745
- Testing
- Audio-based behavioral activation intervention, Audio-based self-monitoring intervention
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Penn State University
Child Maltreatment
New Parent Support Program Evaluation
The purpose of this study is to perform a program evaluation of the Navy and Marine Corps' New Parent Support Program (NPSP) home-visiting option.
- Trial name
- NCT05236192
- Testing
- Take Root Home Visitation (TRHV), Services as Usual (SAU)
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Penn State University
Alcohol Consumption, Sexually Transmitted Diseases
Engineering an Online STI Prevention Program: RCT
The overall objective of the proposed research is to reduce the incidence of sexually transmitted infections (STIs) among college students.
- Trial name
- NCT04095065
- Testing
- itMatters, itMatters and itMatters Sexual Violence Prevention, itMatters Well-being and itMatters Sexual Violence Prevention
- Where
- 4 sites in United States
- Volunteers
- 3,098 people, healthy volunteers welcome
- Sponsor
- Penn State University
Weight Loss, Food Selection
Identifying Changes in Food Behaviors Associated With Beginning GLP-1 Medication
In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss.
- Trial name
- NCT06843512
- Testing
- GLP-1 Medication Initiation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Penn State University