Clinical trials: sponsored by Region Skane
Opioid Dependence, Overdose
Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access
Opioid dependence, for example involving addiction to injected or inhaled heroin or similar compounds, is associated with high mortality, typically from opioid overdose, and causes major physical and mental health complications…
- Trial name
- NCT05678036
- Testing
- Opioid maintenance treatment
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Region Skane
Achilles Tendon Rupture
A Pilot Study on Exercise After Achilles Tendon Rupture
The purpose is to study the effect of early NEuroMuscular EXercise (NEMEX) versus conventional treatment (late exercise) in patients with acute non-operative achilles tendon rupture (ATR).
- Trial name
- NEMEX-ATR (NCT01298024)
- Testing
- Early Neuromuscular Exercise
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Skane
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Osteoarthritis, Knee
RSA Study of Persona TKA With CR vs MC Polyethylene
The aim of this study is to evaluate, over a 2 year period, the migration pattern, function and the possibility of anatomical reconstruction of a relatively new total knee arthroplasty (TKA) concept, the Persona.
- Trial name
- NCT03494348
- Testing
- Medial Congruent Polyethylene (MC)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Skin Structures and Soft Tissue Infections, Wound Infection
The PLUS Study: Comparison of VicrylPlus® Versus Vicryl® for Repair of Perineal Tears
INTRODUCTION It is estimated that over 80% of women who give vaginal birth will sustain some form of perineal tear and of these 60-70% will require suturing.
- Trial name
- NCT02863874
- Testing
- VicrylPlus®, Vicryl®
- Where
- Sweden
- Volunteers
- 1,890 people
- Sponsor
- Region Skane
Breech Presentation; Before Labor
Spinal Anesthesia for External Cephalic Version
This study evaluates the potential benefits of spinal anaesthesia for nulliparous mothers scheduled for external version of babies in breech position.
- Trial name
- NCT03797833
- Testing
- Spinal Anaesthesia
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Cancer
Clinical Evaluation of a New Cancer Diagnosis Center at Kristianstad General Hospital, Sweden
The aim of this study is to evaluate a new cancer diagnosis center (Diagnostiskt Centrum, DC) in Kristianstad, Sweden. Patients aged ≥ 18 years who are suspected of having serious illness but who have no organ-specific symptoms…
- Trial name
- CPF-DC (NCT01709539)
- Testing
- Diagnostiskt Centrum
- Where
- 2 sites in Sweden
- Volunteers
- 388 people
- Sponsor
- Region Skane
Gambling Disorder, Gaming Disorder
GamReg Sweden - Quality Register for Gambling and Gaming Disorders
This is a quality register for the monitoring of clinical assessment and treatment for gambling disorder and gaming disorder in Swedish health care.
- Trial name
- NCT05276193
- Testing
- Observational health care register - no applicable intervention at present
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Region Skane
Gastrointestinal Neoplasms
EUS-Endodrill vs. EUS-FNA for Diagnosis of Submucosal Tumors in the Upper GI Tract
Endodrill is a new instrument for biopsy sampling in the GI-channel. The purpose of this study is as follows: Compare EUS-guided Endodrill biopsies with endoscopic ultrasound guided fine needle aspiration (EUS-FNA) in terms of…
- Trial name
- NCT02744651
- Testing
- EUS-FNA, EUS-Endodrill biopsy
- Where
- Sweden
- Volunteers
- 4 people
- Sponsor
- Region Skane
Sore Throat, Dysuria
Digital Online Consultations - Effects on Antibiotic Prescribing and Health Care Utilization in Primary Care
BACKGROUND/SIGNIFICANCE: With developments in mobile health and the abundance of smartphones, online consultations have emerged as a popular form of primary care in Sweden.
- Conditions
- Sore Throat, Dysuria, Cough, Common Cold
- Trial name
- DOCACUP (NCT03474887)
- Testing
- Physical Consultation, Online Consultation
- Where
- Sweden
- Volunteers
- 4,057 people
- Sponsor
- Region Skane
Fatty Liver
Supplementation of Probiotics and Fruit Fibre to Patients With Fatty Liver
Probiotics and fruit fibre are given for 12 weeks to patients with fatty liver disease. The hypothesis is that probiotic bacteria and fruit fibre affect the gut microbial composition in a positive manner.
- Trial name
- NCT01423630
- Testing
- Probiotics and fruit fibre
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Region Skane
Cardiac Surgery
Effects of Extra Corporeal Circuit Prime on Electrolytes Balance and Clinical Outcome Following Cardiac Surgery
About 6000 heart operations are performed in Sweden every year. A heart-lung machine is used almost exclusively in all heart operations. This machine fills the role of heart and lungs during surgery while the heart is stopped.
- Trial name
- Prime (NCT03302286)
- Testing
- Heart-lung machine primining solution which includes Mannitol, Heart-lung machine primining solution which does not include Mannitol
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Region Skane
Mechanical Complications of Central Venous Catheter
Mechanical Complications After Central Venous Catheterisation
Central venous catheters are common in modern health care and are being increasingly used in both intensive care units and general wards.
- Trial name
- CVC-MECH (NCT03782324)
- Where
- Sweden
- Volunteers
- 12,600 people
- Sponsor
- Region Skane
Septic Shock
Velocity Time Integral vs PICCO for Evaluation of Passive Leg Raising in Septic Shock
The objective of the present study is to investigate accuracy of changes in cardiac output following passive leg raising as estimated by transthoracic ultrasound as method to predict fluid responsiveness and compare that to…
- Trial name
- VIPS (NCT03621449)
- Where
- 2 sites in Sweden
- Sponsor
- Region Skane
Tumor Sampling
Investigation to Evaluate Safety and Efficacy of the Endodrill Model X Biopsy Instrument
This is an investigator led prospective open label investigation, performed at three clinics in Sweden, comparing the flexible endoscopic biopsy instrument Endodrill Model X with the standard sampling method endoscopic ultrasound…
- Trial name
- NCT04519138
- Testing
- Endodrill Model X, Fine-needle aspiration/biopsy
- Where
- 3 sites in Sweden
- Volunteers
- 7 people
- Sponsor
- Region Skane
Heart Arrest, Out-Of-Hospital, Physical Activity
Physical Activity After Cardiac Arrest; a Sub-study in the Target Temperature Management Trial 2
The Target Temperature Management trial 2 (TTM2) is an international multi-center study, that randomize patients with OHCA of a presumed cardiac or unknown cause to target temperature management at 33°C or normothermia but…
- Trial name
- NCT03543332
- Testing
- Measures of physical activity and kinesiophobia
- Where
- 8 sites in Denmark, Sweden and 1 more
- Volunteers
- 109 people
- Sponsor
- Region Skane
Sphincter (Anal); Perineal Rupture, Obstetric, Perineal Tear
One Plus One Equals Two, Will That do?
A new clinical practice to reduce perineal trauma has been adopted by many maternity wards in Sweden. This practice involves collegial midwifery assistance during the second stage of labor and the birth of the baby.
- Conditions
- Sphincter (Anal); Perineal Rupture, Obstetric, Perineal Tear, Pelvic Floor Disorders, Experience, Life
- Trial name
- Oneplus (NCT03770962)
- Testing
- Two midwives
- Where
- 4 sites in Sweden
- Volunteers
- 3,058 people
- Sponsor
- Region Skane
Asphyxia Neonatorum
Fentanyl and Clonidine for Analgesia During Hypothermia in Term Asphyxiated Infants
A prospective pharmacokinetic (PK), pharmacodynamic (PD) and pharmacogenetic (PG) observation study, including the PK/PD/PG relationship, in fentanyl and clonidine administered for analgesia and sedation to term newborn…
- Trial name
- SANNI 1 (NCT03177980)
- Testing
- Fentanyl, Fentanyl and clonidine
- Where
- 2 sites in Sweden
- Volunteers
- 49 people
- Sponsor
- Region Skane
Covid19
The Application of a Mask in Patients With Severe Covid-19 Already Treated With High-flow Nasal Cannula.
Patients with severe hypoxemic respiratory failure due to Covid-19 are often treated with oxygen delivered through a high-flow nasal cannula (HFNC). This is according to guidelines.
- Trial name
- NCT04794400
- Testing
- oxygen mask
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Region Skane
Surgical Site Infection, Patient Satisfaction
Effect of Surgical Site Infections on Patient Reported Cosmetic Outcomes in Dermatologic Surgery
This study involves surveying two matched groups of patients that underwent dermatologic surgery at our department. One group had a documented surgical site infection and the other didn't.
- Trial name
- NCT04744961
- Testing
- SCAR-Q survey
- Where
- Sweden
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Region Skane