Clinical trials: sponsored by Region Skane
Thyroid Neoplasms, Thyroid Cancer
Sentinel Lymphnode in Patients With Papillary Thyroid Carcinoma and in Patients With Suspected Thyroid Neoplasia
The standard surgical treatment for highly differentiated papillary thyroid cancer > 10 mm according to recent national and international guidelines, is total thyroidectomy and central lymphnode clearance, and for patients with…
- Trial name
- SNTC (NCT01089335)
- Testing
- Histological investigation of the SN
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Region Skane
Heart Failure
Combining Myocardial Strain and Cardiac CT to Optimize Left Ventricular Lead Placement in CRT Treatment
For patients with advanced heart failure, Cardiac Resynchronization Therapy (CRT) has been a major improvement. The treatment improves symptoms and prolongs life in selected patients with heart failure.
- Trial name
- CRT clinic (NCT01426321)
- Testing
- Imaging guided LV lead positioning
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Region Skane
Osteoarthritis, Knee
Unloader One Study on Knee Osteoarthritis Hässleholm Sweden
The purpose of this study is to assess the effect of the Unloader one brace on the clinical symptoms of patients with knee osteoarthritis (OA) by comparing a functioning brace with a dummy.
- Trial name
- NCT03454776
- Testing
- Unloader One brace
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Region Skane
Endometrial Neoplasms
Sentinel Lymph Node Detection in Endometrial Cancer
In endometrial cancer (EC) pelvic and paraaortic lymphadenectomy is performed only in high risk groups (with approximately 20% of patients having lymph node metastases (LNM)) whereas no lymphadenectomy is recommended in low risk…
- Trial name
- NCT02690259
- Testing
- Sentinel node procedure
- Where
- Sweden
- Volunteers
- 257 people
- Sponsor
- Region Skane
Sentinel Lymph Node, Endometrial Cancer
Sentinel Node Detection in Endometrial Cancer: A Consolidation Study on Detection Rates of Metastatic Disease
Evaluation of removal of Sentinel lymph nodes only for detection of pelvic lymph node metastases in high risk and low risk endometrial cancer.
- Conditions
- Sentinel Lymph Node, Endometrial Cancer, Lymphedema
- Trial name
- NCT03838055
- Testing
- Injection of tracer ( ICG) and detection of sentinel lymph nodes
- Where
- Sweden
- Volunteers
- 362 people
- Sponsor
- Region Skane
Gastric Tumor
Flexible Endoscopy Biopsies for Submucous Tumors With a New Drill Instrument
The purpose of this study is to determine whether the newly constructed CE (Conformité Européenne) marked drill biopsy instrument for flexible endoscopes can make possible representative biopsies of the increasing numbers of…
- Trial name
- NCT02161029
- Testing
- Flexible drill biopsy instrument, conventional biopsy instrument
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Region Skane
Breast Cancer
Added Value of Contrast Enhanced Spectral Mammography, CESM. A Pilot Study.
Introduction: To avoid unnecessary mastectomies and reoperations a correct size assessment of malignant lesions in breast is required. Sometimes a supplementary MRI is therefore recommended.
- Trial name
- NCT03402529
- Testing
- Contrast Enhanced Spectral Mammography
- Where
- Sweden
- Volunteers
- 47 people
- Sponsor
- Region Skane
Chronic Rhinosinusitis (Diagnosis)
Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Chronic rhinosinusitis (CRS) is a disease associated with impaired quality of life and substantial societal costs. Though sometimes co-appearing with other conditions, such as asthma, allergy, and nasal polyps, many cases present…
- Trial name
- NCT03122795
- Testing
- Microbiome transplant
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Region Skane
Depression Suicidal
Diclofenac add-on to Treatment as Usual for Suicidal Patients
The purpose of this study is to determine whether diclofenac is effective in the treatment of depressed patients with a recent suicide attempt.
- Trial name
- NCT01413854
- Testing
- sugar pill, Diclofenac
- Where
- Sweden
- Sponsor
- Region Skane
Rheumatoid Arthritis, Spondylarthropathy
Effects of Different Antirheumatic Treatments of Arthritis on Antibody Response Following Vaccination Using Prevenar®
Previous studies have analyzed serological responses following pneumococcal vaccination using 23-valent vaccination (Pneumovax) in Rheumatoid Arthritis (RA) patients that were on different therapeutic modalities including…
- Trial name
- PVA (NCT00828997)
- Testing
- Prevenar vaccination
- Where
- Sweden
- Volunteers
- 505 people
- Sponsor
- Region Skane
Stomach Neoplasms
Endodrill vs. Conventional Biopsy. Evaluation of Diagnostic Capacity in Diffuse Gastric Cancer
Endodrill is a new instrument for biopsy sampling in the GI-channel. The purpose of this study is as follows: Compare the Endodrill instrument with conventional biopsy forceps in terms of ability to establish the correct…
- Trial name
- NCT02594943
- Testing
- Boston Scientific Large Capacity with needle Biopsy, Endodrill 1A (BIBBInstruments, Lund, Sweden)
- Sponsor
- Region Skane
Carpal Tunnel Syndrome
Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome
Between 2008 and 2012 the investigators performed a single-center randomized double-blind placebo-controlled trial to assess the efficacy of local injection of two different doses of methylprednisolone (80 mg and 40 mg) in…
- Trial name
- NCT02652390
- Testing
- Methylprednisolone 80 mg, Methylprednisolone 40 mg, Saline
- Volunteers
- 111 people
- Sponsor
- Region Skane
Abortion, Spontaneous
Optimal Treatment of Miscarriage
The main objective of the study is to determine if there is a difference in the number of women with a complete miscarriage after 10 days between expectant management versus treatment with 800 micrograms of misoprostol…
- Trial name
- NCT01033903
- Testing
- misoprostol
- Where
- Sweden
- Volunteers
- 190 people
- Sponsor
- Region Skane
RA, SLE
Vaccination in Inflammatory Rheumatic Disease (VACCIMIL). The Impact of Antirheumatic Treatment on Antibody Response
The overall objective of this project is to study the influence of modern anti-inflammatory treatments in established inflammatory rheumatic diseases (IRD) on immune response elicited by pneumococcal vaccination using 13-valent…
- Conditions
- RA, SLE, Vasculitis, Scleroderma
- Trial name
- Vaccimil (NCT02240888)
- Testing
- 0,5 mg Prevenar i.m., 0,5 mg seasonal influenza vaccine i.m.
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Skane
Type 2 Diabetes, Impaired Glucose Tolerance
Efficiency and Cost-effectiveness of a Culturally Adopted Lifestyle Intervention Program - the MEDIM Study.
An increasing proportion of Sweden's population comprises non-European immigrants, who constitute a high risk-population for T2D.
- Conditions
- Type 2 Diabetes, Impaired Glucose Tolerance, Obesity, Physical Activity
- Trial name
- MEDIM (NCT01420198)
- Testing
- Lifestyle intervention
- Where
- Sweden
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Region Skane
Sentinel Lymph Node Biopsy
Sentinel Node Detection in Cervical Cancer
Evaluation of sensitivity of Sentinel lymph nodes for detecting nodal metastases in cervical cancer
- Trial name
- SLNcxca (NCT03680833)
- Testing
- Sentinel node detection in cervical cancer
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Region Skane
Chronic Anal Fissure
Percutaneous Tibial Nerve Stimulation - an Alternative Treatment Option for Chronic Therapy Resistant Anal Fissure
At a tertiary referral centre, 10 patients (4 male and 6 female; mean age 49.8 years) were given neuromodulation via the posterior tibial nerve to the sacral nerve for 30 min on 10 consecutive days.
- Trial name
- NCT03554421
- Testing
- Percutaneous tibial nerve stimulation
- Volunteers
- 10 people
- Sponsor
- Region Skane
Osteoarthritis
Evaluation of Bisphosphonate Coated Pins for Extern Fixation in Tibia Osteotomy
The purpose of this study is to evaluate the relative osseomechanical strength of a novel coated pin/screw in a clinical model.
- Trial name
- PFX (NCT01745276)
- Testing
- Biphosfonate, Hydroxylapatit
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Skane
Rapid Response System, Vital Signs
The National Early Warning Score: Preceding Dynamics in the Score for Those Who Suffer an In-hospital Cardiac Arrest
To this date no clinical evaluation reports of the dynamics in the National Early Warning Score (NEWS) for those patients who suffer an in-hospital cardiac arrest, IHCA, exists.
- Trial name
- NCT03143062
- Testing
- NEWS
- Where
- Sweden
- Volunteers
- 381 people
- Sponsor
- Region Skane
Thyroid Neoplasms, Carcinoma
Avastin and Doxorubicin Postoperatively for Patients With Anaplastic Thyroid Cancer
Anaplastic Thyroid Cancer is a very aggressive disease. The investigators believe that angiogenesis is very important for these tumors to progress. Preclinical data is suggesting this.
- Conditions
- Thyroid Neoplasms, Carcinoma, Thyroid Cancer, Metastatic Cancer
- Trial name
- NCT00804830
- Testing
- Bevacizumab
- Where
- 3 sites in Sweden
- Volunteers
- 15 people
- Sponsor
- Region Skane